Article
Immunology
Erin Sparrow, James G. Wood, Christopher Chadwick, Anthony T. Newall, Siranda Torvaldsen, Ann Moen, Guido Torelli
Summary: The study compares global capacity for production of influenza vaccines in 2019, showing a slight increase in annual seasonal influenza vaccine production capacity and a rising trend in potential annual influenza pandemic vaccine production capacity. However, these estimates should be interpreted cautiously as they are based on assumptions that may impact supply. Pandemic vaccines would not be immediately available, taking four to six months for initial supplies with further time needed to reach maximum capacity.
Article
Immunology
Sudha Chivukula, Timothy Plitnik, Timothy Tibbitts, Shrirang Karve, Anusha Dias, Donghui Zhang, Rebecca Goldman, Hardip Gopani, Asad Khanmohammed, Ashish Sarode, Dustin Cooper, Heesik Yoon, Younghoon Kim, Yanhua Yan, Sophia T. Mundle, Rachel Groppo, Adrien Beauvais, Jinrong Zhang, Natalie G. Anosova, Charles Lai, Lu Li, Gregory Ulinski, Peter Piepenhagen, Joshua DiNapoli, Kirill Kalnin, Victoria Landolfi, Ron Swearingen, Tong-Ming Fu, Frank DeRosa, Danilo Casimiro
Summary: The recent approval of mRNA vaccines for emergency use against COVID-19 is likely to accelerate the development of mRNA-based vaccines targeting a wide range of infectious diseases. This vaccine modality promises comparable potency while accelerating the development and deployment of vaccine doses. Demonstrated successfully for single antigen vaccines, the technology could be optimized for complex multi-antigen vaccines.
Article
Multidisciplinary Sciences
Zachary J. Madewell, Rafael Chacon-Fuentes, Jorge Jara, Homer Mejia-Santos, Ida-Berenice Molina, Juan Pablo Alvis-Estrada, Rosa Coello-Licona, Belinda Montejo
Summary: Influenza vaccination was well accepted among postpartum women in Honduras, with 78.1% receiving the vaccine. Factors associated with higher vaccination rates included receiving recommendations from healthcare workers during prenatal check-ups, having concurrent chronic diseases, and having other children in the household vaccinated. Main reasons for vaccination included perceived benefits for both mother and infant and easy access, while reasons for non-vaccination included vaccine not being offered and fear of side effects or harm to the infant. Increasing clinician recommendations and ensuring vaccine availability during prenatal visits may help increase vaccination rates.
Article
Public, Environmental & Occupational Health
Gillian K. SteelFisher, Hannah L. Caporello, Cheryl S. Broussard, Thomas J. Schafer, Eran N. Ben-Porath, Robert J. Blendon
Summary: The majority of obstetrician-gynecologists support seasonal flu vaccination for pregnant women, but safety concerns are a significant issue for both the doctors and their patients. Older doctors, those in smaller practices, and those without academic affiliation are more likely to have concerns about the vaccine and less likely to recommend it.
JOURNAL OF WOMENS HEALTH
(2021)
Article
Health Care Sciences & Services
Hojatolah Najafi, Zahra Kavosi, Mahnaz Rakhshan, Jalal Karimi, Milad Ahmadi Marzale, Mostafa Bijani, Mahmoudreza Peyravi
Summary: The aim of this study was to identify the key issues of senior managers' preparedness to respond to the COVID-19 epidemic from the Iranian senior managers' point of view. The analysis of data resulted in the identification of five themes and twelve sub-themes, including capacity improvement, resource and infrastructure management, increase in epidemiology capacity, application of disaster and emergency management principles, and society resilience increase. The study results can help policymakers and health system managers to plan for future outbreaks.
BMC HEALTH SERVICES RESEARCH
(2023)
Article
Sport Sciences
Richelle M. Williams, Hayley J. Root, Tamara C. Valovich McLeod
Summary: Most athletic administrators in Iowa secondary schools reported access to athletic trainers, adherence to state-mandated concussion guidelines, and presence of AEDs on campus. However, levels of annual emergency action plan review and practice were found to be low, highlighting the need for educational opportunities to improve safety policies in schools.
JOURNAL OF ATHLETIC TRAINING
(2021)
Article
Public, Environmental & Occupational Health
Yingwei Yang
Summary: This study examines the impact of violence experiences, safety concerns, and substance use behaviors on youth firearm carriage. The findings show that violence experiences have a significant influence on gun carrying in both female and male adolescents, while substance use behaviors only affect males.
Article
Multidisciplinary Sciences
Yasin M. Yasin, Albara Alomari, Wilma ten Ham-Baloyi, Samaneh Alinejad Mofrad, Lorna J. Moxham, Elizabeth J. Halcomb, Ritin Fernandez
Summary: Despite emotional and educational challenges, participants in this study felt that their education prepared them for clinical practice. Innovative strategies and unique educational experiences used by educators enhanced participants' clinical skills and readiness for practice.
Article
Anthropology
Rosalie Pronk, D. L. Willems, S. van de Vathorst
Summary: Physician-assisted death for mentally ill patients is allowed in the Netherlands, but the role of relatives is not legally defined. This study explores the experiences of relatives with regards to a PAD request by mentally ill patients. Relatives showed ambivalence towards the patient's request, understanding their desire for death while also hoping for a different choice. Some expressed the desire for greater involvement in the PAD process, believing it should be a joint trajectory. Professional support during or after the process was desired by some, but not all.
CULTURE MEDICINE AND PSYCHIATRY
(2023)
Article
Immunology
Zachary J. Madewell, Rafael Chacon-Fuentes, Xiomara Badilla-Vargas, Catalina Ramirez, Maria-Renee Ortiz, Juan-Pablo Alvis-Estrada, Jorge Jara
Summary: This study investigated the knowledge, attitudes, and practices of postpartum women and prenatal care physicians in Costa Rica regarding seasonal influenza vaccination. The results showed a low vaccination rate among pregnant women, highlighting the need to improve vaccination coverage and provide vaccines during prenatal care.
Article
Multidisciplinary Sciences
Nour Abed Elhadi Shahbari, Anat Gesser-Edelsburg, Nadav Davidovitch, Shuli Brammli-Greenberg, Gustavo S. Mesch
Summary: This study examines the impact of parental risk perceptions, health literacy, and school-located vaccination programs on seasonal influenza vaccination uptake. The findings reveal that factors such as perceived influenza risk, perceived vaccination risk, inclusion in the school-located vaccination program, and health literacy influence vaccination uptake among both Arab and Jewish populations. Moreover, positive attitudes toward vaccinations, low risk perceptions regarding the vaccine, and low health literacy that impedes information-seeking are associated with higher influenza vaccination uptake. The study emphasizes the importance of enhancing health literacy among minority groups to enable mothers to make informed decisions about vaccination.
Article
Biotechnology & Applied Microbiology
Obianuju Genevieve Aguolu, Kathryn Willebrand, Jad A. Elharake, Hanya M. Qureshi, Moses Chapa Kiti, Carol Y. Liu, Ana Restrepo Mesa, Kristin Nelson, Samuel Jenness, Alessia Melegaro, Faruque Ahmed, Inci Yildirim, Fauzia A. Malik, Benjamin Lopman, Saad B. Omer
Summary: Influenza causes significant harm in the US, but the vaccination rate among adults is below the target. Understanding factors influencing vaccination acceptance is crucial for promotion and reducing work absences. This study found that education and race are significant predictors of vaccine acceptance. Most participants have favorable attitudes and are influenced by physician recommendations. Qualitative analysis revealed different promotion themes.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Article
Biotechnology & Applied Microbiology
Lauren Ramjee, William Lemay, Nesrin Vurgun, Nathalie Charland, Chris T. Bauch, Gokul Raj Pullagura, Sherilyn K. D. Houle, Gabriel Tremblay
Summary: The analysis suggests that plant-derived QVLP influenza vaccines in Canada may lead to greater reductions in influenza cases and related outcomes, such as hospitalizations and deaths, compared to egg-derived vaccines. In both population subgroups studied, QVLP vaccines demonstrated a significant decrease in influenza burden and overall better effectiveness in preventing illness and severe outcomes. Further scenario analyses indicated potential additional benefits with increased vaccine coverage.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Mathematical & Computational Biology
Nutcha Wattanachit, Evan L. Ray, Thomas C. McAndrew, Nicholas G. Reich
Summary: Three different methods of influenza forecasting were compared in terms of their performance during the 2016/2017, 2017/2018, and 2018/2019 influenza seasons. The use of beta transformation in the models was found to produce more accurate predictions and reduce the impact of the flu epidemic.
STATISTICS IN MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Cheryl Cohen, Jackie Kleynhans, Jocelyn Moyes, Meredith L. McMorrow, Florette K. Treurnicht, Orienka Hellferscee, Azwifarwi Mathunjwa, Anne von Gottberg, Nicole Wolter, Neil A. Martinson, Kathleen Kahn, Limakatso Lebina, Katlego Mothlaoleng, Floidy Wafawanaka, Francesc Xavier Gomez-Olive, Thulisa Mkhencele, Angela Mathee, Stuart Piketh, Brigitte Language, Stefano Tempia
Summary: This study evaluated the burden and transmission of influenza in rural and urban settings in South Africa, finding that children, individuals with mild symptoms, and individuals with severe symptoms were more likely to transmit influenza.
LANCET GLOBAL HEALTH
(2021)