The Roles of HIF-1α in Radiosensitivity and Radiation-Induced Bystander Effects Under Hypoxia

Understanding High-Dose, Ultra-High Dose-Rate and , Spatially Fractionated Radiotherapy

(2020) Robert J. Griffin et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

History and current perspectives on the biological effects of high-dose spatial fractionation and high dose-rate approaches: GRID, Microbeam & FLASH radiotherapy

(2020) Robert J Griffin et al.   BRITISH JOURNAL OF RADIOLOGY

Imaging of Tumor Hypoxia for Radiotherapy: Current Status and Future Directions

(2020) Morten Busk et al.   SEMINARS IN NUCLEAR MEDICINE

Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges

(2019) Muhammad Zaeem Noman et al.   Cells

The Radiation-Induced Bystander Effect (RIBE) and its Connections with the Hallmarks of Cancer

(2019) Aisling B. Heeran et al.   RADIATION RESEARCH

Tumor Oxygenation and Hypoxia Inducible Factor-1 Functional Inhibition via a Reactive Oxygen Species Responsive Nanoplatform for Enhancing Radiation Therapy and Abscopal Effects

(2018) Lingtong Meng et al.   ACS Nano

The Impact of Hypoxia on Out-of-Field Cell Survival after Exposure to Modulated Radiation Fields

(2017) Hannah F. Thompson et al.   RADIATION RESEARCH

Cancer stem cells: The root of tumor recurrence and metastases

(2017) Claudia Peitzsch et al.   SEMINARS IN CANCER BIOLOGY

Estrogen-induced disruption of intracellular iron metabolism leads to oxidative stress, membrane damage, and cell cycle arrest in MCF-7 cells

(2017) Khuloud Bajbouj et al.   TUMOR BIOLOGY

Regulation of HIF1  under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models

(2016) D. P. Logsdon et al.   MOLECULAR CANCER THERAPEUTICS

Systemic mechanisms and effects of ionizing radiation: A new ⿿old⿿ paradigm of how the bystanders and distant can become the players

(2016) Zacharenia Nikitaki et al.   SEMINARS IN CANCER BIOLOGY

Protective effect of mild endoplasmic reticulum stress on radiation-induced bystander effects in hepatocyte cells

(2016) Yuexia Xie et al.   Scientific Reports

The differential role of human macrophage in triggering secondary bystander effects after either gamma-ray or carbon beam irradiation

(2015) Chen Dong et al.   CANCER LETTERS

SirT1 knockdown potentiates radiation-induced bystander effect through promoting c-Myc activity and thus facilitating ROS accumulation

(2015) Yuexia Xie et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Biology of Hypoxia

(2015) Paul N. Span et al.   SEMINARS IN NUCLEAR MEDICINE

Hypoxia-induced autophagy reduces radiosensitivity by the HIF-1α/miR-210/Bcl-2 pathway in colon cancer cells

(2014) YONG SUN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Differential Expression of Stress and Immune Response Pathway Transcripts and miRNAs in Normal Human Endothelial Cells Subjected to Fractionated or Single-Dose Radiation

(2014) Sanjeewani T. Palayoor et al.   MOLECULAR CANCER RESEARCH

Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8

(2014) G.-O. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007

(2013) Rheal A. Towner et al.   NEURO-ONCOLOGY

Cytochrome-c mediated a bystander response dependent on inducible nitric oxide synthase in irradiated hepatoma cells

(2012) M He et al.   BRITISH JOURNAL OF CANCER

Differential expression of HIF-1 in glioblastoma multiforme and anaplastic astrocytoma

(2012) ARNULF MAYER et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Imaging hypoxia to improve radiotherapy outcome

(2012) Michael R. Horsman et al.   Nature Reviews Clinical Oncology

Suppression of Endogenous Hydrogen Sulfide Contributes to the Radiation-Induced Bystander Effects on Hypoxic HepG2 Cells

(2012) Jianghong Zhang et al.   RADIATION RESEARCH

Overexpression of carbonic anhydrase and HIF-1α in Wilms tumours

(2011) Josiah V Dungwa et al.   BMC CANCER

Out-of-Field Cell Survival Following Exposure to Intensity-Modulated Radiation Fields

(2011) Karl T. Butterworth et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Hydrogen Sulfide Contributes to Hypoxia-induced Radioresistance on Hepatoma Cells

(2011) Jianghong ZHANG et al.   JOURNAL OF RADIATION RESEARCH

Connexin40 Modulates Pulmonary Permeability Through Gap Junction Channel in Acute Lung Injury After Thoracic Gunshot Wounds

(2010) Qiang Li et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

The Yield, Processing, and Biological Consequences of Clustered DNA Damage Induced by Ionizing Radiation

(2009) Naoya SHIKAZONO et al.   JOURNAL OF RADIATION RESEARCH

Systemic effects of local radiotherapy

(2009) Silvia C Formenti et al.   LANCET ONCOLOGY

Estrogen enhanced cell-cell signalling in breast cancer cells exposed to targeted irradiation

(2008) Chunlin Shao et al.   BMC CANCER

Chromosomal Instability in Unirradiated Hemaopoietic Cells Induced by Macrophages Exposed In vivo to Ionizing Radiation

(2008) S. A. Lorimore et al.   CANCER RESEARCH

Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

(2008) J. Chiche et al.   CANCER RESEARCH

Irradiated fibroblast-induced bystander effects on invasive growth of squamous cell carcinoma under cancer-stromal cell interaction

(2008) Noriyuki Kamochi et al.   CANCER SCIENCE

Radiation-induced bystander effects enhanced by elevated sodium chloride through sensitizing cells to bystander factors

(2008) Lingyan Zhu et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Expression profiles are different in carbon ion-irradiated normal human fibroblasts and their bystander cells

(2008) Mayumi Iwakawa et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Hypoxic tumor cell radiosensitization through nitric oxide

(2008) Mark De Ridder et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Regulation of cancer cell metabolism by hypoxia-inducible factor 1

(2008) Gregg L. Semenza   SEMINARS IN CANCER BIOLOGY

Signaling factors for irradiated glioma cells induced bystander responses in fibroblasts

(2007) Chunlin Shao et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS