Gut-derived acetate promotes B10 cells with antiinflammatory effects

B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids

(2020) Helia N. Sanchez et al.   Nature Communications

Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells

(2020) Elizabeth C. Rosser et al.   Cell Metabolism

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

(2019) Maik Luu et al.   Nature Communications

BCR-dependent lineage plasticity in mature B cells

(2019) Robin Graf et al.   SCIENCE

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms

(2019) Joseph Castillo et al.   CANCER RESEARCH

CD24hiCD38hi and CD24hiCD27+ Human Regulatory B Cells Display Common and Distinct Functional Characteristics

(2019) Md Mahmudul Hasan et al.   JOURNAL OF IMMUNOLOGY

Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake

(2018) Lewin Small et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fructose bisphosphatase 2 overexpression increases glucose uptake in skeletal muscle

(2018) Ishita Bakshi et al.   JOURNAL OF ENDOCRINOLOGY

B1a B cells require autophagy for metabolic homeostasis and self-renewal

(2018) Alexander J. Clarke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation

(2018) Mohsen Sarikhani et al.   eLife

IL-10 Producing B Cells Ability to Induce Regulatory T Cells Is Maintained in Rheumatoid Arthritis

(2018) Julie Mielle et al.   Frontiers in Immunology

Role of Short Chain Fatty Acids in Controlling Tregs and Immunopathology During Mucosal Infection

(2018) Natarajan Bhaskaran et al.   Frontiers in Microbiology

Gut Microbial Metabolites Fuel Host Antibody Responses

(2016) Myunghoo Kim et al.   Cell Host & Microbe

Memory CD8 + T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function

(2016) Maria L. Balmer et al.   IMMUNITY

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways

(2016) Jian Tan et al.   Cell Reports

Glycogen synthase kinase-3 controls IL-10 expression in CD4+ effector T-cell subsets through epigenetic modification of the IL-10 promoter

(2015) Elaine V. Hill et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory B Cells: Origin, Phenotype, and Function

(2015) Elizabeth C. Rosser et al.   IMMUNITY

B10 Cells: A Functionally Defined Regulatory B Cell Subset

(2015) Thomas F. Tedder   JOURNAL OF IMMUNOLOGY

Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites

(2015) Alison N. Thorburn et al.   Nature Communications

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

(2015) Laurence Macia et al.   Nature Communications

Characterization of tumor-associated B-cell subsets in patients with colorectal cancer

(2015) Alexander Shimabukuro-Vornhagen et al.   Oncotarget

Th17 and regulatory T cell balance in autoimmune and inflammatory diseases

(2014) Mélissa Noack et al.   AUTOIMMUNITY REVIEWS

Regulatory B cells are induced by gut microbiota–driven interleukin-1β and interleukin-6 production

(2014) Elizabeth C Rosser et al.   NATURE MEDICINE

The growing landscape of lysine acetylation links metabolism and cell signalling

(2014) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

Regulatory B10 Cells Are Decreased in Patients With Rheumatoid Arthritis and Are Inversely Correlated With Disease Activity

(2014) Claire I. Daien et al.   Arthritis & Rheumatology

Short-Chain Fatty Acids Activate GPR41 and GPR43 on Intestinal Epithelial Cells to Promote Inflammatory Responses in Mice

(2013) Myung H. Kim et al.   GASTROENTEROLOGY

Central Nervous System Expression and PET Imaging of the Translocator Protein in Relapsing-Remitting Experimental Autoimmune Encephalomyelitis

(2013) F. Mattner et al.   JOURNAL OF NUCLEAR MEDICINE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

A cross-platform toolkit for mass spectrometry and proteomics

(2012) Matthew C Chambers et al.   NATURE BIOTECHNOLOGY

Interleukin 1 receptor antagonist mediates the beneficial effects of systemic interferon beta in mice: implications for rheumatoid arthritis

(2011) M. Corr et al.   ANNALS OF THE RHEUMATIC DISEASES

Mice Lacking Endogenous IL-10-Producing Regulatory B Cells Develop Exacerbated Disease and Present with an Increased Frequency of Th1/Th17 but a Decrease in Regulatory T Cells

(2011) N. A. Carter et al.   JOURNAL OF IMMUNOLOGY

Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naïve/memory Breg ratio during a relapse but not in remission

(2011) Stephanie Knippenberg et al.   JOURNAL OF NEUROIMMUNOLOGY

The Role of Glycogen Synthase Kinase 3 in Regulating IFN- -Mediated IL-10 Production

(2010) H. Wang et al.   JOURNAL OF IMMUNOLOGY

Image-Quality Assessment for Several Positron Emitters Using the NEMA NU 4-2008 Standards in the Siemens Inveon Small-Animal PET Scanner

(2010) J. A. Disselhorst et al.   JOURNAL OF NUCLEAR MEDICINE

Bioavailability of Acetate from Two Vinegar Supplements: Capsule and Drink

(2010) Shino SUGIYAMA et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE