Diabetes Mellitus Promotes Atrial Structural Remodeling and PARP-1/Ikkα/NF-κB Pathway Activation in Mice

DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation

(2019) Deli Zhang et al.   Nature Communications

Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007–2017

(2018) Thomas R. Einarson et al.   Cardiovascular Diabetology

Data linking diabetes mellitus and atrial fibrillation–how strong is the evidence? From epidemiology and pathophysiology to therapeutic implications

(2018) Răzvan C. Șerban et al.   CANADIAN JOURNAL OF CARDIOLOGY

The role of immune cells in atrial fibrillation

(2018) Yaozhong Liu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiomyocyte Inflammasome Signaling in Cardiomyopathies and Atrial Fibrillation: Mechanisms and Potential Therapeutic Implications

(2018) Gong Chen et al.   Frontiers in Physiology

PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis

(2018) Maayan Waldman et al.   EXPERIMENTAL CELL RESEARCH

PARP1 orchestrates epigenetic events setting up chromatin domains

(2017) Fabio Ciccarone et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Left Atrial Reverse Remodeling

(2017) Liza Thomas et al.   JACC-Cardiovascular Imaging

Polydatin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation by inhibiting NF-κB/NLRP3 inflammasome activation via the AMPK/SIRT1 pathway

(2017) Lvyi Chen et al.   Food & Function

Cross-talk between macrophages and atrial myocytes in atrial fibrillation

(2016) Zewei Sun et al.   BASIC RESEARCH IN CARDIOLOGY

Acute blood glucose fluctuation enhances rat aorta endothelial cell apoptosis, oxidative stress and pro-inflammatory cytokine expression in vivo

(2016) Na Wu et al.   Cardiovascular Diabetology

Assessment of Mitochondrial Dysfunction and Monoamine Oxidase Contribution to Oxidative Stress in Human Diabetic Hearts

(2016) O. M. Duicu et al.   Oxidative Medicine and Cellular Longevity

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

Diabetes mellitus and atrial fibrillation: Pathophysiological mechanisms and potential upstream therapies

(2015) Christos A. Goudis et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Chromatin to Clinic: The Molecular Rationale for PARP1 Inhibitor Function

(2015) Felix Y. Feng et al.   MOLECULAR CELL

Inflammation and the pathogenesis of atrial fibrillation

(2015) Yu-Feng Hu et al.   Nature Reviews Cardiology

Probucol Prevents Atrial Remodeling by Inhibiting Oxidative Stress and TNF-α/NF-κB/TGF-β Signal Transduction Pathway in Alloxan-Induced Diabetic Rabbits

(2014) HUAYING FU et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Atrial Remodeling and Atrial Fibrillation

(2014) Stanley Nattel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone

(2014) U. M. Muthurajan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of the Ras homolog gene family (Rho), member A/Rho associated coiled-coil forming protein kinase pathway in atrial fibrosis of type 2 diabetes in rats

(2014) JINLING CHEN et al.   Experimental and Therapeutic Medicine

Advanced glycation end-products impair Na+/K+-ATPase activity in diabetic cardiomyopathy: Role of the adenosine monophosphate-activated protein kinase/sirtuin 1 pathway

(2013) Qiong Yuan et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Beyond DNA Repair: Additional Functions of PARP-1 in Cancer

(2013) Alice N. Weaver et al.   Frontiers in Oncology

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice

(2012) M. Y. Kim et al.   DIABETOLOGIA

Sirt-1 Is Required for the Inhibition of Apoptosis and Inflammatory Responses in Human Tenocytes

(2012) Franziska Busch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type 2 diabetes, glucose homeostasis and incident atrial fibrillation: the Atherosclerosis Risk in Communities study

(2011) Rachel R Huxley et al.   HEART

Atrial Substrate Properties and Outcome of Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation Associated With Diabetes Mellitus or Impaired Fasting Glucose

(2010) Tze-Fan Chao et al.   AMERICAN JOURNAL OF CARDIOLOGY

Substrate-Specific Derangements in Mitochondrial Metabolism and Redox Balance in the Atrium of the Type 2 Diabetic Human Heart

(2009) Ethan J. Anderson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Nuclear Poly(ADP-Ribose)-Dependent Signalosome Confers DNA Damage-Induced IκB Kinase Activation

(2009) Michael Stilmann et al.   MOLECULAR CELL

Impact of New-Onset Diabetes Mellitus on Development of Atrial Fibrillation and Heart Failure in High-Risk Hypertension (from the VALUE Trial)

(2008) Tonje Amb Aksnes et al.   AMERICAN JOURNAL OF CARDIOLOGY

PARP mediates structural alterations in diabetic cardiomyopathy

(2008) Jane Chiu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY