Partitioning and Spatial Distribution of Drugs in Ocular Surface Tissues

Comprehensive Ocular and Systemic Pharmacokinetics of Brinzolamide in Rabbits After Intracameral, Topical, and Intravenous Administration

(2020) Vatsala Naageshwaran et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Topical ocular pharmacokinetics and bioavailability for a cocktail of atenolol, timolol and betaxolol in rabbits

(2020) Anam Fayyaz et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

MALDI imaging mass spectrometry revealed atropine distribution in the ocular tissues and its transit from anterior to posterior regions in the whole-eye of rabbit after topical administration

(2019) Naoto Mori et al.   PLoS One

Distribution of small molecular weight drugs into the porcine lens: studies on imaging mass spectrometry, distribution coefficients, and implications in ocular pharmacokinetics

(2019) Emma M. Heikkinen et al.   MOLECULAR PHARMACEUTICS

Role of retinal pigment epithelium permeability in drug transfer between posterior eye segment and systemic blood circulation

(2019) Eva Ramsay et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Detection of small molecule concentration gradients in ocular tissues and humours

(2019) Berin A. Boughton et al.   JOURNAL OF MASS SPECTROMETRY

Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye

(2018) Eva Ramsay et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The penetration and distribution of topical atropine in animal ocular tissues

(2018) Louis Zizhao Wang et al.   ACTA OPHTHALMOLOGICA

Impact of Chemical Structure on Conjunctival Drug Permeability: Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model

(2017) Eva Ramsay et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Application of Imaging Mass Spectrometry to Assess Ocular Drug Transit

(2017) Kerri J. Grove et al.   SLAS Discovery

Determination of permeability coefficients of ophthalmic drugs through different layers of porcine, rabbit and bovine eyes

(2012) Christian Loch et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Prediction of the Corneal Permeability of Drug-Like Compounds

(2010) Heidi Kidron et al.   PHARMACEUTICAL RESEARCH