A Multi-Omics Analysis of Metastatic Melanoma Identifies a Germinal Center-Like Tumor Microenvironment in HLA-DR-Positive Tumor Areas

Functional heterogeneity of lymphocytic patterns in primary melanoma dissected through single-cell multiplexing

(2020) Francesca Maria Bosisio et al.   eLife

Cutaneous Melanoma, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology

(2019) Daniel G. Coit et al.   Journal of the National Comprehensive Cancer Network

High-Plex Predictive Marker Discovery for Melanoma Immunotherapy–Treated Patients Using Digital Spatial Profiling

(2019) Maria I. Toki et al.   CLINICAL CANCER RESEARCH

Benchmark and integration of resources for the estimation of human transcription factor activities

(2019) Luz Garcia-Alonso et al.   GENOME RESEARCH

Expressions of HLA Class II Genes in Cutaneous Melanoma Were Associated with Clinical Outcome: Bioinformatics Approaches and Systematic Analysis of Public Microarray and RNA-Seq Datasets

(2019) Yang-Yi Chen et al.   Diagnostics

Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of anti-PD-1 Therapies in Metastatic Melanoma

(2018) Douglas B. Johnson et al.   CLINICAL CANCER RESEARCH

Immune-Related Adverse Events Associated with Immune Checkpoint Blockade

(2018) Michael A. Postow et al.   NEW ENGLAND JOURNAL OF MEDICINE

MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma

(2018) Scott J. Rodig et al.   Science Translational Medicine

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

(2018) Peng Jiang et al.   NATURE MEDICINE

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

(2018) Noam Auslander et al.   NATURE MEDICINE

MHC expression predicts response

(2018) Peter Sidaway   Nature Reviews Clinical Oncology

UniProt: a worldwide hub of protein knowledge

(2018)   NUCLEIC ACIDS RESEARCH

Survival Outcomes in Patients With Previously Untreated BRAF Wild-Type Advanced Melanoma Treated With Nivolumab Therapy

(2018) Paolo A. Ascierto et al.   JAMA Oncology

LAG3 (CD223) as a cancer immunotherapy target

(2017) Lawrence P. Andrews et al.   IMMUNOLOGICAL REVIEWS

IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade

(2017) Mark Ayers et al.   JOURNAL OF CLINICAL INVESTIGATION

Multiplex Staining by Sequential Immunostaining and Antibody Removal on Routine Tissue Sections

(2017) Maddalena Maria Bolognesi et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006)

(2017) Jacob Schachter et al.   LANCET

Data-analysis strategies for image-based cell profiling

(2017) Juan C Caicedo et al.   NATURE METHODS

histoCAT: analysis of cell phenotypes and interactions in multiplex image cytometry data

(2017) Denis Schapiro et al.   NATURE METHODS

Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy

(2016) Douglas B. Johnson et al.   Nature Communications

Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4 + T- Cells, Which Dampen CD8 + T-cell Antitumor Reactivity

(2015) Marco Donia et al.   CANCER RESEARCH

Interleukin-12: Functional activities and implications for disease

(2015) Sebastian Zundler et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

(2015) E. M. Van Allen et al.   SCIENCE

Batf is important for IL-4 expression in T follicular helper cells

(2015) Anupama Sahoo et al.   Nature Communications

The controversial role of TNF in melanoma

(2015) Marco Donia et al.   OncoImmunology

Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti-PD-1 Therapy

(2014) J. M. Taube et al.   CLINICAL CANCER RESEARCH

Transcription Factor IRF4 Regulates Germinal Center Cell Formation through a B Cell-Intrinsic Mechanism

(2014) S. N. Willis et al.   JOURNAL OF IMMUNOLOGY

PD-1 blockade induces responses by inhibiting adaptive immune resistance

(2014) Paul C. Tumeh et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

(2013) Nadia J Kershaw et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods

(2013) Leif Väremo et al.   NUCLEIC ACIDS RESEARCH

Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

(2012) J. M. Taube et al.   Science Translational Medicine

Regression of melanoma metastases after immunotherapy is associated with activation of antigen presentation and interferon-mediated rejection genes

(2011) Rafael Carretero et al.   INTERNATIONAL JOURNAL OF CANCER

Effects of human leukocyte antigen (HLA)-DR engagement on melanoma cells

(2011) Giovanna Barbieri   INTERNATIONAL JOURNAL OF ONCOLOGY

A novel ELISA for measuring CD36 protein in human adipose tissue

(2010) Carolyn C. Allred et al.   JOURNAL OF LIPID RESEARCH

DistinctMHCgene expression patterns during progression of melanoma

(2009) Yan Degenhardt et al.   GENES CHROMOSOMES & CANCER

Coexpression of major histocompatibility complex class II with chemokines and nuclear NFκB p50 in melanoma: a rational for their association with poor prognosis

(2009) Isabelle Martins et al.   MELANOMA RESEARCH