Telomeres in Interstitial Lung Disease

Molecular Markers of Telomere Dysfunction and Senescence are Common Findings in the Usual Interstitial Pneumonia Pattern of Lung Fibrosis

(2021) Joyce S. Lee et al.   HISTOPATHOLOGY

From organ to cell: Multi-level telomere length assessment in patients with idiopathic pulmonary fibrosis

(2020) Aernoud A. van Batenburg et al.   PLoS One

Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells

(2020) Neha Nagpal et al.   Cell Stem Cell

Telomere length in patients with unclassifiable interstitial lung disease: a cohort study

(2020) Brett Ley et al.   EUROPEAN RESPIRATORY JOURNAL

Familial Interstitial Lung Disease

(2020) Jonathan A. Kropski   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Interstitial lung abnormalities detected incidentally on CT: a Position Paper from the Fleischner Society

(2020) Hiroto Hatabu et al.   Lancet Respiratory Medicine

Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita

(2020) Siddharth Shukla et al.   Blood Advances

Safety and efficacy of pirfenidone and nintedanib in patients with Idiopathic Pulmonary Fibrosis and carrying a telomere related gene mutation

(2020) Aurélien Justet et al.   EUROPEAN RESPIRATORY JOURNAL

Telomere Length and Genetic Variant Associations with Interstitial Lung Disease Progression and Survival

(2019) Chad A. Newton et al.   EUROPEAN RESPIRATORY JOURNAL

Telomere Biology and Human Phenotype

(2019) Kara Turner et al.   Cells

The Aging Lung and Idiopathic Pulmonary Fibrosis

(2019) Swati Gulati et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Lung Transplant Outcomes in Patients With Pulmonary Fibrosis With Telomere-Related Gene Variants

(2019) Aparna C. Swaminathan et al.   CHEST

Rare Protein-altering Telomere-related Gene Variants in Patients with Chronic Hypersensitivity Pneumonitis

(2019) Brett Ley et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The genetics of interstitial lung diseases

(2019) Raphael Borie et al.   European Respiratory Review

Pilot experience of multidisciplinary team discussion dedicated to inherited pulmonary fibrosis

(2019) Raphael Borie et al.   Orphanet Journal of Rare Diseases

Pulmonary phenotypes associated with genetic variation in telomere-related genes

(2018) Thijs W. Hoffman et al.   CURRENT OPINION IN PULMONARY MEDICINE

Clinical implications of telomere dysfunction in lung fibrosis

(2018) Maria Molina-Molina et al.   CURRENT OPINION IN PULMONARY MEDICINE

Safety and efficacy of pirfenidone in patients carrying telomerase complex mutation

(2018) Aurélien Justet et al.   EUROPEAN RESPIRATORY JOURNAL

Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres

(2018) Juan Manuel Povedano et al.   eLife

Analysis of protein-altering variants in telomerase genes and their association with MUC5B common variant status in patients with idiopathic pulmonary fibrosis: a candidate gene sequencing study

(2018) Amy Dressen et al.   Lancet Respiratory Medicine

Telomere length measurement as a clinical biomarker of aging and disease

(2018) Clare L. Fasching   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Telomere Length and Use of Immunosuppressive Medications in Idiopathic Pulmonary Fibrosis

(2018) Chad A. Newton et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulator of telomere length 1 (RTEL1) mutations are associated with heterogeneous pulmonary and extra-pulmonary phenotypes

(2018) Raphael Borie et al.   EUROPEAN RESPIRATORY JOURNAL

Pulmonary fibrosis: Genetic analysis of telomere-related genes, telomere length measurement-or both?

(2018) Caroline Kannengiesser et al.   RESPIROLOGY

Predictive factors and prognostic effect of telomere shortening in pulmonary fibrosis

(2018) Lurdes Planas-Cerezales et al.   RESPIROLOGY

Cigarette smoking and telomere length: A systematic review of 84 studies and meta-analysis

(2017) Yuliana Astuti et al.   ENVIRONMENTAL RESEARCH

Pleuroparenchymal fibroelastosis associated with telomerase reverse transcriptase mutations

(2017) Hilario Nunes et al.   EUROPEAN RESPIRATORY JOURNAL

Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis

(2017) Pierre-Antoine Juge et al.   EUROPEAN RESPIRATORY JOURNAL

Telomere length in patients with pulmonary fibrosis associated with chronic lung allograft dysfunction and post–lung transplantation survival

(2017) Chad A. Newton et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Short telomere length in IPF lung associates with fibrotic lesions and predicts survival

(2017) Reinier Snetselaar et al.   PLoS One

The MUC5B promoter polymorphism and telomere length in patients with chronic hypersensitivity pneumonitis: an observational cohort-control study

(2017) Brett Ley et al.   Lancet Respiratory Medicine

Telomeres and Cell Senescence - Size Matters Not

(2017) Stella Victorelli et al.   EBioMedicine

Prevalence and characteristics ofTERTandTERCmutations in suspected genetic pulmonary fibrosis

(2016) Raphael Borie et al.   EUROPEAN RESPIRATORY JOURNAL

Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive

(2016) Chad A. Newton et al.   EUROPEAN RESPIRATORY JOURNAL

Danazol Treatment for Telomere Diseases

(2016) Danielle M. Townsley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association of Donor and Recipient Telomere Length with Clinical Outcomes following Lung Transplantation

(2016) Andrew M. Courtwright et al.   PLoS One

Telomerase Regulation from Beginning to the End

(2016) Deanna MacNeil et al.   Genes

Extensive Phenotyping of Individuals at Risk for Familial Interstitial Pneumonia Reveals Clues to the Pathogenesis of Interstitial Lung Disease

(2015) Jonathan A. Kropski et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rare Variants inRTEL1Are Associated with Familial Interstitial Pneumonia

(2015) Joy D. Cogan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Telomere Length in Interstitial Lung Diseases

(2015) Reinier Snetselaar et al.   CHEST

The MUC5B Promoter Polymorphism Is Associated With Idiopathic Pulmonary Fibrosis in a Mexican Cohort but Is Rare Among Asian Ancestries

(2015) Anna L. Peljto et al.   CHEST

Short Telomeres, Telomeropathy, and Subclinical Extrapulmonary Organ Damage in Patients With Interstitial Lung Disease

(2015) Gautam George et al.   CHEST

Exome Sequencing Identifies Mutant TINF2 in a Family With Pulmonary Fibrosis

(2015) Jonathan K. Alder et al.   CHEST

HeterozygousRTEL1mutations are associated with familial pulmonary fibrosis

(2015) Caroline Kannengiesser et al.   EUROPEAN RESPIRATORY JOURNAL

Clinical outcomes of lung transplant recipients with telomerase mutations

(2015) Sofya Tokman et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Severe hematologic complications after lung transplantation in patients with telomerase complex mutations

(2015) Raphael Borie et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening

(2015) Bridget D Stuart et al.   NATURE GENETICS

Telomere dysfunction causes alveolar stem cell failure

(2015) Jonathan K. Alder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association between telomere length and survival in patients with idiopathic pulmonary fibrosis

(2015) Jinghong Dai et al.   RESPIROLOGY

The molecular genetics of the telomere biology disorders

(2015) Alison A. Bertuch   RNA Biology

Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction

(2015) Juan M. Povedano et al.   Cell Reports

Response to androgen therapy in patients with dyskeratosis congenita

(2014) Payal P. Khincha et al.   BRITISH JOURNAL OF HAEMATOLOGY

A Novel Dyskerin ( DKC1 ) Mutation Is Associated With Familial Interstitial Pneumonia

(2014) Jonathan A. Kropski et al.   CHEST

Lung transplantation in telomerase mutation carriers with pulmonary fibrosis

(2014) L. L. Silhan et al.   EUROPEAN RESPIRATORY JOURNAL

Direct Comparison of Flow-FISH and qPCR as Diagnostic Tests for Telomere Length Measurement in Humans

(2014) Fernanda Gutierrez-Rodrigues et al.   PLoS One

Rheumatoid arthritis-related interstitial lung disease: associations, prognostic factors and physiological and radiological characteristics--a large multicentre UK study

(2014) C. A. Kelly et al.   RHEUMATOLOGY

Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation

(2014) Bridget D Stuart et al.   Lancet Respiratory Medicine

An Official American Thoracic Society/European Respiratory Society Statement: Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias

(2013) William D. Travis et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Telomerase and Telomere Length in Pulmonary Fibrosis

(2013) Tianju Liu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Haematological recovery in dyskeratosis congenita patients treated with danazol

(2013) Amin Islam et al.   BRITISH JOURNAL OF HAEMATOLOGY

Predicting Survival Across Chronic Interstitial Lung Disease

(2013) Christopher J. Ryerson et al.   CHEST

Update on the diagnosis and classification of ILD

(2013) Christopher J. Ryerson et al.   CURRENT OPINION IN PULMONARY MEDICINE

Telomeres and age-related disease: how telomere biology informs clinical paradigms

(2013) Mary Armanios   JOURNAL OF CLINICAL INVESTIGATION

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis

(2013) Tasha E Fingerlin et al.   NATURE GENETICS

A Novel Telomerase Activator Suppresses Lung Damage in a Murine Model of Idiopathic Pulmonary Fibrosis

(2013) Claude Jourdan Le Saux et al.   PLoS One

Association between MUC5B and TERT polymorphisms and different interstitial lung disease phenotypes

(2013) Rongrong Wei et al.   Translational Research

Smoking-Related Interstitial Lung Diseases

(2011) Robert Vassallo et al.   CLINICS IN CHEST MEDICINE

Telomere Lengths, Pulmonary Fibrosis and Telomerase (TERT) Mutations

(2010) Alberto Diaz de Leon et al.   PLoS One

Telomere Shortening in Familial and Sporadic Pulmonary Fibrosis

(2008) Jennifer T. Cronkhite et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Short telomeres are a risk factor for idiopathic pulmonary fibrosis

(2008) J. K. Alder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dyskeratosis congenita: The diverse clinical presentation of mutations in the telomerase complex

(2007) T.J. Vulliamy et al.   BIOCHIMIE