Development of a CD8 co-receptor independent T-cell receptor specific for tumor-associated antigen MAGE-A4 for next generation T-cell-based immunotherapy

A Fas-4-1BB fusion protein converts a death to a pro-survival signal and enhances T cell therapy

(2020) Shannon K. Oda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Engineered T Cell Therapy for Cancer in the Clinic

(2019) Lijun Zhao et al.   Frontiers in Immunology

Preclinical evaluation of an affinity-enhanced MAGE-A4-specific T-cell receptor for adoptive T-cell therapy

(2019) Joseph P Sanderson et al.   OncoImmunology

CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer

(2019) Ryan Zander et al.   IMMUNITY

Targeting cancers through TCR-peptide/MHC interactions

(2019) Qinghua He et al.   Journal of Hematology & Oncology

Role of Mechanotransduction and Tension in T Cell Function

(2018) Jérémie Rossy et al.   Frontiers in Immunology

Immune Checkpoint Inhibitors: Basics and Challenges

(2017) Bin Li et al.   CURRENT MEDICINAL CHEMISTRY

T-Cell Therapy Using Interleukin-21–Primed Cytotoxic T-Cell Lymphocytes Combined With Cytotoxic T-Cell Lymphocyte Antigen-4 Blockade Results in Long-Term Cell Persistence and Durable Tumor Regression

(2016) Aude G. Chapuis et al.   JOURNAL OF CLINICAL ONCOLOGY

Gapped sequence alignment using artificial neural networks: application to the MHC class I system

(2015) Massimo Andreatta et al.   BIOINFORMATICS

Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo

(2015) D Sommermeyer et al.   LEUKEMIA

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice

(2015) Matthias Obenaus et al.   NATURE BIOTECHNOLOGY

NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma

(2015) Aaron P Rapoport et al.   NATURE MEDICINE

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression

(2015) Jelle Scholtalbers et al.   Genome Medicine

Expression and Immune Responses to MAGE Antigens Predict Survival in Epithelial Ovarian Cancer

(2014) Sayeema Daudi et al.   PLoS One

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma

(2013) G. P. Linette et al.   BLOOD

Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy

(2013) Richard A. Morgan et al.   JOURNAL OF IMMUNOTHERAPY

Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia

(2013) Stephan A. Grupp et al.   NEW ENGLAND JOURNAL OF MEDICINE

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo

(2012) S. Spranger et al.   BLOOD

Different affinity windows for virus and cancer-specific T-cell receptors: Implications for therapeutic strategies

(2012) Milos Aleksic et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Coreceptor-Independent Transgenic Human TCR Mediates Anti-Tumor and Anti-Self Immunity in Mice

(2012) S. Mehrotra et al.   JOURNAL OF IMMUNOLOGY

Long-term Persistence of CD4+ but Rapid Disappearance of CD8+ T Cells Expressing an MHC Class I-restricted TCR of Nanomolar Affinity

(2012) Boris Engels et al.   MOLECULAR THERAPY

Generation of allo-restricted peptide-specific T cells using RNA-pulsed dendritic cells

(2012) Susanne Wilde et al.   OncoImmunology

TCR cross-reactivity and allorecognition: new insights into the immunogenetics of allorecognition

(2011) L. J. D’Orsogna et al.   IMMUNOGENETICS

The biology of cancer testis antigens: Putative function, regulation and therapeutic potential

(2011) Elisabetta Fratta et al.   Molecular Oncology

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

(2011) Antonio Di Stasi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors

(2010) Matthias Leisegang et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of CD154 in haematopoietic development

(2010) Tom Seijkens et al.   THROMBOSIS AND HAEMOSTASIS

Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity

(2009) S. Wilde et al.   BLOOD

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

(2009) L. A. Johnson et al.   BLOOD

Cancer/testis (CT) antigens: Potential targets for immunotherapy

(2009) Otavia L. Caballero et al.   CANCER SCIENCE

Antigen choice in adoptive T-cell therapy of cancer

(2009) Rienk Offringa   CURRENT OPINION IN IMMUNOLOGY

Inhibitory Effect of RNA Pool Complexity on Stimulatory Capacity of RNA-pulsed Dendritic Cells

(2009) Miran Javorovic et al.   JOURNAL OF IMMUNOTHERAPY

CD137-guided isolation and expansion of antigen-specific CD8 cells for potential use in adoptive immunotherapy

(2008) Kazue Watanabe et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY