Article
Chemistry, Applied
Linfan Shi, Jingyi Zhou, Jiayue Guo, Isabella Gladden, Lingyan Kong
Summary: Linear starch can form inclusion complexes with small molecules, which can be used for encapsulation and controlled release of bioactive compounds, showing potential as a delivery system.
CARBOHYDRATE POLYMERS
(2021)
Article
Food Science & Technology
Chenxi Wang, David Julian McClements, Aiquan Jiao, Jinpeng Wang, Zhengyu Jin, Chao Qiu
Summary: This review highlights the recent advances in the green synthesis and applications of resistant starch (RS) and its nanoparticles. The potential effects of RS and its nanoparticles on the human gastrointestinal tract (GIT) and health are discussed, including their ability to inhibit amylase, delay gastric emptying, exhibit prebiotic effects, and act as colon specific delivery systems for bioactive agents.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Food Science & Technology
Sadia Aslam, Aqsa Akhtar, Nilesh Nirmal, Nauman Khalid, Sajid Maqsood
Summary: Bioactive compounds are sensitive to degradation, limiting their applications in food and pharmaceutical products. Encapsulation in starch-based carrier systems can protect their bioactivity and ensure the sensory properties of products.
FOOD ENGINEERING REVIEWS
(2022)
Review
Food Science & Technology
Safoura Ahmadzadeh, Matthias Dixily R. Lenie, Razieh Sadat Mirmahdi, Ali Ubeyitogullari
Summary: This article introduces the 3D printing-based encapsulation approach, which incorporates bioactive compounds precisely into three-dimensional matrices to provide protection, enhanced bioavailability, and effective delivery.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Shanshan Tie, Siyuan Xiang, Yannan Chen, Fengzhi Qiao, Weina Cui, Wentao Su, Mingqian Tan
Summary: In this study, food-grade nanocarriers were prepared using a one-pot method, which exhibited controllable sizes and good antioxidant capacity. The nanocarriers also showed inhibitory effects on cell damage and could be used for delivering active ingredients.
Article
Engineering, Chemical
Junjun Zhou, Yaqing Bian, Tongliang Yang, Jiake Wang, Tianai Kong, Yifu Zhang, Ye Chen, Shuhong Li
Summary: In this study, zein nanoparticles were modified using cold plasma technology, resulting in more uniform distribution and ordered secondary structure. The modified nanoparticles had smaller size and larger zeta-potential. As a delivery wall material, they exhibited improved interactions with curcumin, leading to enhanced release property, encapsulation efficiency, pH and ionic strength stability.
JOURNAL OF FOOD ENGINEERING
(2023)
Review
Plant Sciences
Anastasia Kyriakoudi, Eleni Spanidi, Ioannis Mourtzinos, Konstantinos Gardikis
Summary: Plant-derived phytochemicals have proven biological activity but face challenges such as low stability and poor solubility. Various delivery systems have been developed to enhance the stability and solubility of these compounds, delivering them efficiently to target tissues for biological activity and human health promotion.
Review
Polymer Science
Giovani Leone Zabot, Fabiele Schaefer Rodrigues, Lissara Polano Ody, Marcus Vinicius Tres, Esteban Herrera, Heidy Palacin, Javier S. Cordova-Ramos, Ivan Best, Luis Olivera-Montenegro
Summary: This review presents the current findings and advancements in the encapsulation of bioactive compounds for food and agricultural applications. Various polymers and methods of encapsulation have been investigated, and the main compounds encapsulated in the food and agricultural areas have been discussed. Encapsulation can be efficient for the formulation of biofungicides, biopesticides, bioherbicides, and biofertilizers in the agricultural sector.
Article
Biophysics
Pablo Mendez-Pfeiffer, Josue Juarez, Javier Hernandez, Pablo Taboada, Claudia Virues, Efrain Alday, Dora Valencia, Carlos Velazquez
Summary: The study aimed to synthesize Poly-(lactide-co-glycolide) acid (PLGA) nanoparticles for encapsulation of Sonoran propolis (SP) and evaluate their antiproliferative activity on cancer cells. The results showed that SP-PLGA nanoparticles exhibited significant inhibitory effects on cancer cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Kamal Essifi, Mohamed Brahmi, Doha Berraaouan, Abderrahim Ed-Daoui, Ali El Bachiri, Marie-Laure Fauconnier, Abdesselam Tahani
Summary: By studying the effect of alginate concentration on the properties and release characteristics of microcapsules, it was found that increasing polymer concentration can enhance encapsulation efficiency while reducing loading capacity. The release kinetics are dependent on the structure and physicochemical properties of the encapsulated molecules.
JOURNAL OF CHEMISTRY
(2021)
Article
Polymer Science
Robabbeh Sanatkar, Ghasem Rahimi Kalateh Shah Mohammad, Ehsan Karimi, Ehsan Oskoueian, Rudi Hendra
Summary: This study synthesized chitosan-encapsulated daidzein and evaluated its releasing behavior in simulated gastrointestinal fluids, demonstrating its inhibitory effects on human colon cancer cells and angiogenesis. The microcapsules showed good stability and high entrapment efficiency, with gradual release in stomach and intestinal fluid and substantial release in colonic fluid. Additionally, the microcapsules induced apoptotic cell death in cancer cells while showing no significant cytotoxicity to normal fibroblast cells.
Review
Pharmacology & Pharmacy
Wanting Zhang, Yuxin Jiang, Yonglong He, Hamza Boucetta, Jun Wu, Zhongjian Chen, Wei He
Summary: This study provides an overview of the applications of lipid carriers in mRNA delivery and the development of lipid-based formulations as vaccine delivery systems, with a focus on the recent advancements in COVID-19 mRNA vaccines. It highlights the significance of these advancements in developing effective vaccines and treatment methods.
ACTA PHARMACEUTICA SINICA B
(2023)
Article
Food Science & Technology
Yaning Shi, Shiwen Zhou, Saifeng Fan, Yuhan Ma, Dandan Li, Yang Tao, Yongbin Han
Summary: Polyphenols and starch play important roles in human health. Starch can help to sustain or target-release polyphenols, protecting them from reaching the lower digestive tract and altering the abundance and composition of gut microbiota.
CURRENT OPINION IN FOOD SCIENCE
(2021)
Article
Materials Science, Ceramics
Mohammad Hossein Fekri, Samaneh Soleymani, Maryam Razavi Mehr, Behrouz Akbari-adergani
Summary: A modified straightforward process was introduced to synthesize zinc oxide nanoparticles and fill them into mesoporous silica SBA-16. The study found that the highest percentage of drug adsorption can be achieved by optimizing the factors affecting drug loading, and demonstrated the controlled drug release of SBA-16 loaded with nano ZnO.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2022)
Review
Chemistry, Medicinal
Denisse Gardea-Gutierrez, Eduardo Nunez-Garcia, Berenice E. E. Oseguera-Guerra, Manuel Roman-Aguirre, Silvia L. L. Montes-Fonseca
Summary: Asymmetric liposomes, with their lipid bilayers resembling cell plasma membrane, have attracted interest as a novel lipid-based nanosystem for drug delivery. This review discusses the applications, advantages, and synthesis techniques of asymmetric liposomes, as well as the use of computational tools for designing and understanding their mechanisms in pharmaceutical applications.
Article
Pharmacology & Pharmacy
Maryam Rezvani, Maria Letizia Manca, Aldo Muntoni, Giorgia De Gioannis, Jose Luis Pedraz, Gemma Gutierrez, Maria Matos, Anna Maria Fadda, Maria Manconi
Summary: This study developed whey vesicles loaded with gingerol by using an eco-friendly method, which showed promising effects in protecting intestinal cells and promoting wound healing. Whey vesicles prepared with tragacanth gum demonstrated the highest capability in intestinal protection, highlighting their potential in nanomedicine applications for treating intestinal damages.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Food Science & Technology
Leyla Sanhueza, Paula Garcia, Begona Gimenez, Jose Manuel Benito, Maria Matos, Gemma Gutierrez
Summary: The feasibility of encapsulating pomegranate peel extract in double emulsions was evaluated, and double emulsions prepared by direct membrane emulsification showed better stability and encapsulation efficiency.
Article
Chemistry, Applied
Diana Moran, Gemma Gutierrez, Rafael Mendoza, Marilyn Rayner, Carmen Blanco-Lopez, Maria Matos
Summary: In this study, a microemulsion method was developed to synthesize controlled-size starch nanoparticles (SNPs). The method involved testing different formulations to prepare water-in-oil microemulsions, and the resulting SNPs were characterized in terms of size, morphology, monodispersity, and crystallinity. The method was also used to synthesize starch-based nanocomposites with superparamagnetic properties. This innovative technology shows potential for the design and development of functional nanomaterials.
CARBOHYDRATE POLYMERS
(2023)
Article
Biochemistry & Molecular Biology
Verdiana Marchiano, Maria Matos, Miriam Lopez, Shihan Weng, Esther Serrano-Pertierra, Susana Luque, M. Carmen Blanco-Lopez, Gemma Gutierrez
Summary: Vanillin, a natural compound with various properties, was encapsulated in non-ionic surfactant vesicles. The vesicles were synthesized using thin film hydration and ethanol injection methods. The encapsulation efficiency and loading capacity of the vesicles were evaluated. Furthermore, vanillin-loaded vesicles were incorporated into gelatin films for potential food packing applications. The films were characterized in terms of morphology, water solubility, color, and transparency.
Article
Chemistry, Analytical
Shayesteh Bazsefidpar, Esther Serrano-Pertierra, Gemma Gutierrez, Alberto Sanchez Calvo, Maria Matos, Maria Carmen Blanco-Lopez
Summary: The study developed a sensitive lateral flow immunoassay (LFIA) for rapid detection of Escherichia coli (E. coli) O157:H7, a pathogen responsible for worldwide diseases and fatalities. Gold nanoparticles were synthesized and coated with a carboxylated heterobifunctional PEG polymer to be used as a label in sandwich-LFIA. A silver enhancement strategy was developed to amplify the signal, reducing the limit of detection (LOD). The system demonstrated improved sensitivity compared to the conventional LFIA system and showed effectiveness in quickly detecting pathogenic bacteria in food products.
Article
Chemistry, Analytical
Shayesteh Bazsefidpar, Maria Freitas, Clara R. Pereira, Gemma Gutierrez, Esther Serrano-Pertierra, Henri P. A. Nouws, Maria Matos, Cristina Delerue-Matos, Maria Carmen Blanco-Lopez
Summary: In this paper, a method for effectively controlling Escherichia coli (E. coli) O157:H7 in milk samples was developed. Monodisperse Fe3O4@Au magnetic nanoparticles were synthesized and used in an electrochemical sandwich-type magnetic immunoassay for rapid and accurate analysis. The assay showed a linear range from 20 to 2 x 10(6) CFU/mL, with a limit of detection of 20 CFU/mL for E. coli O157:H7. The selectivity of the assay was tested and the applicability was demonstrated by analyzing a commercial milk sample.
Article
Chemistry, Applied
Florencia Ridella, Ismael Marcet, Gemma Gutierrez, Manuel Rendueles, Mario Diaz
Summary: Delipidated egg yolk proteins were used to prepare stable nanoparticles with excellent antioxidant properties, showing potential as a reliable emulsifying agent.
