Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial

Six years’ experience with LipidSeq: clinical and research learnings from a hybrid, targeted sequencing panel for dyslipidemias

(2020) Jacqueline S. Dron et al.   BMC Medical Genomics

The polygenic nature of mild-to-moderate hypertriglyceridemia

(2020) Jacqueline S. Dron et al.   Journal of Clinical Lipidology

Hypertriglyceridemia-induced acute pancreatitis: A prospective, multicenter, international cohort analysis of 716 acute pancreatitis cases

(2020) Dóra Mosztbacher et al.   PANCREATOLOGY

N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levels

(2019) Veronica J Alexander et al.   EUROPEAN HEART JOURNAL

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk

(2019) François Mach et al.   EUROPEAN HEART JOURNAL

Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome

(2019) Joseph L. Witztum et al.   NEW ENGLAND JOURNAL OF MEDICINE

Roundtable on etiology of familial chylomicronemia syndrome

(2018) William Virgil Brown et al.   Journal of Clinical Lipidology

Clinical and biochemical features of different molecular etiologies of familial chylomicronemia

(2018) Robert A. Hegele et al.   Journal of Clinical Lipidology

Extreme Hypertriglyceridemia: genetic diversity, pancreatitis, pregnancy, and prevalence

(2018) Vadzim Chyzhyk et al.   Journal of Clinical Lipidology

Severe hypertriglyceridemia is primarily polygenic

(2018) Jacqueline S. Dron et al.   Journal of Clinical Lipidology

2016 ESC/EAS Guidelines for the Management of Dyslipidaemias

(2016) Alberico L. Catapano et al.   EUROPEAN HEART JOURNAL

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

(2016) Philip L.S.M. Gordts et al.   JOURNAL OF CLINICAL INVESTIGATION

Acute Pancreatitis is Highly Prevalent and Complications can be Fatal in Patients with Familial Chylomicronemia: Results From a Survey of Lipidologist

(2016) Daniel Gaudet et al.   Journal of Clinical Lipidology

Severe hypertriglyceridemia and factors associated with acute pancreatitis in an integrated health care system

(2016) Nazia Rashid et al.   Journal of Clinical Lipidology

Nonfasting Mild-to-Moderate Hypertriglyceridemia and Risk of Acute Pancreatitis

(2016) Simon B. Pedersen et al.   JAMA Internal Medicine

Elevated Serum Triglycerides are Independently Associated With Persistent Organ Failure in Acute Pancreatitis

(2015) Haq Nawaz et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2

(2015) Terry A. Jacobson et al.   Journal of Clinical Lipidology

Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia

(2015) Daniel Gaudet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease

(2014) Anders Berg Jørgensen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting APOC3 in the Familial Chylomicronemia Syndrome

(2014) Daniel Gaudet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Determining Triglyceride Reductions Needed for Clinical Impact in Severe Hypertriglyceridemia

(2013) Jennifer B. Christian et al.   AMERICAN JOURNAL OF MEDICINE

Treatment options for hypertriglyceridemia: From risk reduction to pancreatitis

(2013) Lars Berglund et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans

(2013) Mark J. Graham et al.   CIRCULATION RESEARCH

A prospective cohort study on risk of acute pancreatitis related to serum triglycerides, cholesterol and fasting glucose

(2013) Björn Lindkvist et al.   PANCREATOLOGY

Acute Pancreatitis in a Cohort of 129 Patients Referred for Severe Hypertriglyceridemia

(2009) Célia Lloret Linares et al.   PANCREAS