PB1 S524G mutation of wild bird-origin H3N8 influenza A virus enhances virulence and fitness for transmission in mammals

Absence of adaptive evolution is the main barrier against influenza emergence in horses in Asia despite frequent virus interspecies transmission from wild birds

(2019) Henan Zhu et al.   PLoS Pathogens

N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses

(2019) Frederik Broszeit et al.   Cell Reports

Identification of Key Amino Acids in the PB2 and M1 Proteins of H7N9 Influenza Virus That Affect Its Transmission in Guinea Pigs

(2019) Huihui Kong et al.   JOURNAL OF VIROLOGY

Mutation W222L at the receptor binding site of hemagglutinin could facilitate viral adaption from equine influenza A(H3N8) virus to dogs

(2018) Feng Wen et al.   JOURNAL OF VIROLOGY

A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs

(2017) Zeng Wang et al.   JOURNAL OF VIROLOGY

Molecular basis of mammalian transmissibility of avian H1N1 influenza viruses and their pandemic potential

(2017) Mark Zanin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human infection with a novel, highly pathogenic avian influenza A (H5N6) virus: Virological and clinical findings

(2016) Ming Pan et al.   JOURNAL OF INFECTION

Identification of the binding roles of terminal and internal glycan epitopes using enzymatically synthesized N-glycans containing tandem epitopes

(2016) Zhigang Wu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Amino acid residues at positions 222 and 227 of the hemagglutinin together with the neuraminidase determine binding of H5 avian influenza viruses to sialyl Lewis X

(2015) Takahiro Hiono et al.   ARCHIVES OF VIROLOGY

Synergistic Effect of S224P and N383D Substitutions in the PA of H5N1 Avian Influenza Virus Contributes to Mammalian Adaptation

(2015) Jiasheng Song et al.   Scientific Reports

Possible basis for the emergence of H1N1 viruses with pandemic potential from avian hosts

(2015) Zeynep A Koçer et al.   Emerging Microbes & Infections

Identification, Characterization, and Natural Selection of Mutations Driving Airborne Transmission of A/H5N1 Virus

(2014) Martin Linster et al.   CELL

Role of receptor binding specificity in influenza A virus transmission and pathogenesis

(2014) M. de Graaf et al.   EMBO JOURNAL

H6 Influenza Viruses Pose a Potential Threat to Human Health

(2014) G. Wang et al.   JOURNAL OF VIROLOGY

Respiratory transmission of an avian H3N8 influenza virus isolated from a harbour seal

(2014) Erik A. Karlsson et al.   Nature Communications

Genetics, Receptor Binding Property, and Transmissibility in Mammals of Naturally Isolated H9N2 Avian Influenza Viruses

(2014) Xuyong Li et al.   PLoS Pathogens

Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses

(2013) Di Liu et al.   LANCET

H5N1 Hybrid Viruses Bearing 2009/H1N1 Virus Genes Transmit in Guinea Pigs by Respiratory Droplet

(2013) Y. Zhang et al.   SCIENCE

H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet

(2013) Q. Zhang et al.   SCIENCE

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

(2012) Masaki Imai et al.   NATURE

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

Emergence of Fatal Avian Influenza in New England Harbor Seals

(2012) S. J. Anthony et al.   mBio

Reassortment and Mutation of the Avian Influenza Virus Polymerase PA Subunit Overcome Species Barriers

(2011) A. Mehle et al.   JOURNAL OF VIROLOGY

The PA Protein Directly Contributes to the Virulence of H5N1 Avian Influenza Viruses in Domestic Ducks

(2010) J. Song et al.   JOURNAL OF VIROLOGY

Adaptation of Pandemic H1N1 Influenza Viruses in Mice

(2010) N. A. Ilyushina et al.   JOURNAL OF VIROLOGY

Isolation and genetic characterization of H3N8 equine influenza virus from donkeys in China

(2010) Ting Qi et al.   VETERINARY MICROBIOLOGY

Equine and canine influenza: a review of current events

(2010) E. Paul J. Gibbs et al.   ANIMAL HEALTH RESEARCH REVIEWS

Isolation and molecular characterization of equine H3N8 influenza viruses from pigs in China

(2009) Jiagang Tu et al.   ARCHIVES OF VIROLOGY

Molecular Determinants of Adaptation of Highly Pathogenic Avian Influenza H7N7 Viruses to Efficient Replication in the Human Host

(2009) E. de Wit et al.   JOURNAL OF VIROLOGY

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Amino Acids in HA and PB2 Critical for the Transmission of H5N1 Avian Influenza Viruses in a Mammalian Host

(2009) Yuwei Gao et al.   PLoS Pathogens

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

(2009) John Steel et al.   PLoS Pathogens

Replication and Transmission of H9N2 Influenza Viruses in Ferrets: Evaluation of Pandemic Potential

(2008) Hongquan Wan et al.   PLoS One

Two amino acid residues in the matrix protein M1 contribute to the virulence difference of H5N1 avian influenza viruses in mice

(2008) Shufang Fan et al.   VIROLOGY