Review
Medicine, General & Internal
Michal Szotek, Lukasz Druzbicki, Karol Sabatowski, Gisella R. Amoroso, Koen De Schouwer, Pawel T. Matusik
Summary: Transcatheter aortic valve implantation (TAVI) has become a widely accepted treatment method for aortic stenosis in patients who are at high surgical risk or disqualified from surgery. However, TAVI is associated with a high incidence of conduction abnormalities, such as heart block, which may require permanent pacemaker implantation. Understanding the risk factors for these complications and providing optimal care is crucial for improving patient outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Fumiaki Yashima, Masahiko Hara, Taku Inohara, Masahiro Jinzaki, Hideyuki Shimizu, Keiichi Fukuda, Makoto Tanaka, Masanori Yamamoto, Yusuke Watanabe, Toru Naganuma, Shinichi Shirai, Masahiro Yamawaki, Norio Tada, Futoshi Yamanaka, Kazuki Mizutani, Hiroshi Ueno, Minoru Tabata, Kensuke Takagi, Kentaro Hayashida
Summary: The study suggests that statin can reduce all-cause mortality and cardiovascular mortality in TAVI patients, especially in octogenarians. Additionally, statin is essential for TAVI patients with coronary artery disease (CAD). Further research is needed to validate and generalize the findings.
Review
Medicine, General & Internal
Stephanie Louise Swift, Thomas Puehler, Kate Misso, Shona Helen Lang, Carol Forbes, Jos Kleijnen, Marion Danner, Christian Kuhn, Assad Haneya, Hatim Seoudy, Jochen Cremer, Norbert Frey, Georg Lutter, Robert Wolff, Fueloep Scheibler, Kai Wehkamp, Derk Frank
Summary: The study compared the benefits and risks of TAVI and SAVR, finding that TAVI may reduce the risk of certain side effects while SAVR may reduce the risk of others. More data is needed to assess the long-term effects for low-risk patients, therefore every SAS patient should engage in SDM to make personalized decisions based on the benefits and risks of each treatment.
Article
Cardiac & Cardiovascular Systems
Michele Pighi, Simone Fezzi, Gabriele Pesarini, Gabriele Venturi, Davide Giovannini, Gianluca Castaldi, Mattia Lunardi, Valeria Ferrero, Roberto Scarsini, Flavio Ribichini
Summary: The increase in EVCD stage was associated with a higher incidence of AKI after TAVI. AKI had a negative impact on long-term clinical outcomes but only in patients with advanced cardiac damage. AKR did not reduce adverse clinical outcomes but was associated with improved renal function at 12 months.
CANADIAN JOURNAL OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Abukar Mohamed Ali, Daanyaal Wasim, Kjetil Halvorsen Loland, Svein Rotevatn, Oyvind Bleie, Sahrai Saeed
Summary: This study focuses on the impact of TAVI on cardiac structure and function in patients with severe AS, aiming to identify echocardiographic predictors of reverse LV remodeling, assess survival benefits based on baseline risk profile, evaluate long-term therapeutic success reflected by reduction in valvular-arterial impedance and investigate the impact of different types of blood pressure response immediately after TAVI on clinical outcome.
Article
Medicine, General & Internal
Bernhard Michels, Andreas Holzamer, Bernhard M. Graf, Andre Bredthauer, Walter Petermichl, Anika Muller, York Alexander Zausig, Diane Inge Bitzinger
Summary: This study found that lower preoperative BChE levels were associated with higher risk of postoperative complications after TAVI. The sustained reduction in BChE activity in the complication group suggests a potential role of BChE as a biomarker for identifying at-risk patients. Predicting the length of hospital stay may be important for efficient management of resources and staff for these patients.
Review
Medicine, General & Internal
Marjan Jahangiri, Rajdeep Bilkhu, Andrew Embleton-Thirsk, Hakim-Moulay Dehbi, Krishna Mani, Jon Anderson, Vassilios Avlonitis, Max Baghai, Inderpaul Birdi, Karen Booth, Amal Bose, Norman Briffa, Keith Buchan, Sunil Bhudia, Alex Cale, Indu Deglurkar, Shakil Farid, Leonidas Hadjinikolaou, Martin Jarvis, Seyed Hossein Javadpour, Reubendra Jeganathan, Manoj Kuduvalli, Kulvinder Lall, Jorge Mascaro, Dheeraj Mehta, Sunil Ohri, Prakash Punjabi, Rajamiyer Venkateswaran, Paul Ridley, Christopher Satur, Serban Stoica, Uday Trivedi, Afzal Zaidi, Patrick Yiu, Narain Moorjani, Simon Kendall, Nick Freemantle
Summary: The study in UK found that patients undergoing SAVR or SAVR + CABG have low mortality risk and complications regardless of age and risk factors. Urgent surgery, poor ventricular function, higher EuroSCORE, and longer cross clamp and cardiopulmonary bypass times were associated with worse outcomes.
Review
Medicine, General & Internal
Simona Sperlongano, Francesca Renon, Maurizio Cappelli Bigazzi, Rossella Sperlongano, Giovanni Cimmino, Antonello D'Andrea, Paolo Golino
Summary: Cardiac rehabilitation (CR) after transcatheter aortic valve implantation (TAVI) can improve exercise tolerance and quality of life in patients, and potentially reduce mortality during follow-up. While major guidelines currently do not recommend CR after TAVI, emerging scientific evidence supports the benefits of such programs.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Medicine, General & Internal
Lola Gutierrez, Mauro Boiago, Chiara De Biase, Omar Oliva, Pietro Laforgia, Souheib Feliachi, Alessandro Beneduce, Nicolas Dumonteil, Didier Tchetche
Summary: Bicuspid aortic valve disease is the most common congenital heart disease, associated with unique morphological features and lack of consensus in sizing measurement. Multi-slice computed tomography plays a crucial role in TAVI procedure planning, and advancements in devices and procedure planning have improved clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Karan Rao, Kunwardeep Bhatia, Bernard Chan, Mitchell Cowan, Natasha Saad, Alexandra Baer, Hari Sritharan, Ingrid Bromhead, David Whalley, Usaid K. Allahwala, Peter Hansen, Ravinay Bhindi
Summary: Aortic stenosis is a common and life-threatening heart valve disease. Transcatheter aortic valve implantation (TAVI) is a less invasive treatment option. However, high-grade atrioventricular conduction block (HGAVB) is a common post-TAVI complication that can lead to syncope or sudden death. This study aims to improve the prediction of HGAVB after TAVI.
Review
Geriatrics & Gerontology
D. Bertschi, C. M. Kiss, A. W. Schoenenberger, A. E. Stuck, R. W. Kressig
Summary: Sarcopenia is highly prevalent among patients undergoing TAVI and negatively affects important outcomes. Early diagnosis and intervention may help prevent adverse outcomes in TAVI patients.
JOURNAL OF NUTRITION HEALTH & AGING
(2021)
Article
Cardiac & Cardiovascular Systems
Taishi Okuno, Daijiro Tomii, Eric Buffle, Jonas Lanz, Christoph Ryffel, Caglayan Demirel, Suliman Hashemi, Daniel Hagemeyer, Athanasios Papadis, Dik Heg, Fabien Praz, Stefan Stortecky, Stephan Windecker, Thomas Pilgrim
Summary: This study aimed to compare the clinical and procedural outcomes of patients with rheumatic aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) with patients undergoing TAVI for degenerative AS. The results showed that the technical success rate and 1-year cardiovascular mortality rate were comparable between patients with rheumatic AS and degenerative AS. However, patients with rheumatic AS had lower rates of 30-day and 1-year cardiovascular mortality compared with patients with degenerative AS.
Article
Cardiac & Cardiovascular Systems
Alberto Alperi, Josep Rodes-Cabau, Matheus Simonato, Didier Tchetche, Gaetan Charbonnier, Henrique B. Ribeiro, Azeem Latib, Matteo Montorfano, Marco Barbanti, Sabine Bleiziffer, Bjorn Redfors, Mohamed Abdel-Wahab, Abdelhakim Allali, Giuseppe Bruschi, Massimo Napodano, Marco Agrifoglio, Anna Sonia Petronio, Cristina Giannini, Albert Chan, Ran Kornowski, Nili Schamroth Pravda, Matti Adam, Alessandro Iadanza, Stephane Noble, Andrew Chatfield, Magdalena Erlebach, Joerg Kempfert, Timm Ubben, Harindra Wijeysundera, Moritz Seiffert, Thomas Pilgrim, Won-Keun Kim, Luca Testa, David Hildick-Smith, Roberto Nerla, Claudia Fiorina, Christina Brinkmann, Lars Conzelmann, Didier Champagnac, Francesco Saia, Henrik Nissen, Hafid Amrane, Brian Whisenant, Jasmin Shamekhi, Lars Sondergaard, John G. Webb, Danny Dvir
Summary: In a large series of ViV-TAVR procedures, the incidence of periprocedural PPI was relatively low and decreased with the use of new-generation THV systems. Older age, larger THV size, and previous right bundle branch block were associated with an increased risk of PPI. Although there were no significant differences in 30-day mortality between the PPI and no-PPI groups, PPI patients exhibited a trend toward higher mortality risk at follow-up.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Shekhar Saha, Sven Peterss, Christoph Mueller, Simon Deseive, Sebastian Sadoni, Jorg Hausleiter, Steffen Massberg, Christian Hagl, Dominik Joskowiak
Summary: This study retrospectively analyzed the surgical outcomes of patients undergoing secondary cardiac surgery after initial TAVR, finding that conventional cardiac surgical procedures following TAVR are feasible with reasonable results and a low complication rate.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Joshua M. Riley, Joey Junarta, Waqas Ullah, Muhammad U. Siddiqui, Alexander Anzelmi, Max Ruge, Alec Vishnevsky, Rene J. Alvarez, Nicholas J. Ruggiero, Indranee N. Rajapreyar, Yevgeniy Brailovsky
Summary: A significant number of patients with concomitant aortic stenosis (AS) and cardiac amyloidosis (CA) are at higher risk of all-cause mortality. This meta-analysis suggests that patients with CA and AS who underwent transcatheter aortic valve implantation (TAVI) had a significantly lower risk of all-cause mortality compared to those managed with medical therapy alone.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)