Article
Plant Sciences
Imran Ul Haq, Siddra Ijaz, Nabeeha Aslam Khan, Iqrar Ahmad Khan, Hayssam M. Ali, Ernesto A. Moya-Elizondo
Summary: In this study, the Integrative Pathogenicity (IP) postulates were developed for authenticated pathogenicity testing in plants by using integrative omics. The researchers confirmed the pathogen causing vascular wilt in datepalm by analyzing genomic and transcriptomic data, and also identified a new forma specialis of F. oxysporum that causes wilt in datepalm.
Article
Microbiology
Sascha Jenkins, Andrew Taylor, Alison C. Jackson, Andrew D. Armitage, Helen J. Bates, Andrew Mead, Richard J. Harrison, John P. Clarkson
Summary: Fusarium oxysporum is a soilborne fungal plant pathogen causing Fusarium wilt disease of pea, with resistant cultivars commonly used for control but facing the risk of pathogen breakdown due to variations. Further research is needed to determine if differences in virulence across a broader set of pea cultivars are related to variations in SIX genes.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Plant Sciences
Megan A. Brenes Guallar, Like Fokkens, Martijn Rep, Lidija Berke, Peter van Dam
Summary: This study presents the updated FoEC2 pipeline, which classifies F. oxysporum strains into formae speciales based on genome assemblies. FoEC2 is more user-friendly, customizable, and scalable than its predecessor. By applying the FoEC2 pipeline to analyze F. oxysporum genomes, the classification of isolates into formae speciales and the identification of their subtypes can be confirmed.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biology
Yu Ayukawa, Shuta Asai, Pamela Gan, Ayako Tsushima, Yasunori Ichihashi, Arisa Shibata, Ken Komatsu, Petra M. Houterman, Martijn Rep, Ken Shirasu, Tsutomu Arie
Summary: The genome sequence of a Fusarium oxysporum isolate contains conditionally dispensable chromosomes which play a crucial role in conferring virulence on specific hosts. The study provides insight into the mechanisms underlying F. oxysporum pathogenicity, particularly in determining host specificity through effector genes on transmissible CD chromosomes.
COMMUNICATIONS BIOLOGY
(2021)
Article
Plant Sciences
Dalia Aiello, Alberto Fiorenza, Giuseppa Rosaria Leonardi, Alessandro Vitale, Giancarlo Polizzi
Summary: The study identified Fusarium nirenbergiae as the causal agent of Fusarium wilt on passion fruit, potentially posing a significant threat to the expanding passion fruit production in Italy and Europe. This pathogen caused symptoms such as yellowing, wilting, and vascular discoloration in crown and stem tissues.
Article
Microbiology
Hengwei Qian, Limin Song, Lulu Wang, Baoshan Wang, Wenxing Liang
Summary: This study identified a peptidase, FoAPY1, secreted by Fusarium oxysporum during plant-pathogen interactions. FoAYP1 contributes to the virulence of F. oxysporum by exerting peptidase activity against host plant proteins.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Horticulture
Erfeng Li, Jiling Xiao, Yuhong Yang, Bingyan Xie, Zhenchuan Mao
Summary: This study investigated the functions of Nto1 in two different races of Fusarium oxysporum through functional genetics analyses, and found that Nto1-deleted mutants showed changes in conidium production, sensitivity to hydrogen peroxide, and virulence on cabbage.
Article
Biotechnology & Applied Microbiology
Govindan Pothiraj, Veerubommu Shanmugam, Aditya Tyagi, Zakir Hussain, Rashmi Aggarwal, Manakkatt Mohan Haritha, Karuppiah Manikandan, Awani Kumar Singh, Gopala Krishnan
Summary: PCR profiling was employed to establish the physiological races of 14 strains of Fusarium oxysporum f.sp. lycopersici. Based on the amplification of the SIX3 gene, 6 strains were identified as race 2 and 8 strains were identified as race 3. The roles of the pathogenicity-related genes Fow1 and Fow2 in fungal pathogenicity and host defense mechanisms were also investigated.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2023)
Review
Plant Sciences
Qussai Zuriegat, Yuru Zheng, Hong Liu, Zonghua Wang, Yingzi Yun
Summary: Fusarium oxysporum is a soilborne plant pathogen that secretes various virulence factors and must respond to stresses from the environment and host during infection. Research has identified 26 functionally characterized transcription factors in F. oxysporum, with 23 playing important roles in pathogenicity, particularly the largest family being zinc finger TF family.
MOLECULAR PLANT PATHOLOGY
(2021)
Article
Plant Sciences
Hengwei Qian, Lulu Wang, Baoshan Wang, Wenxing Liang
Summary: The secreted RNase protein FoRnt2 from Fusarium oxysporum plays an important role in the virulence of the pathogen by degrading plant RNA and enhancing plant susceptibility to pathogens.
MOLECULAR PLANT PATHOLOGY
(2022)
Article
Multidisciplinary Sciences
Linxuan Li, Tingting Zhu, Yun Song, Li Feng, Philip James Kear, Rooallah Saberi Riseh, Mahmoud Sitohy, Raju Datla, Maozhi Ren
Summary: This study explored the potential mechanisms of salicylic acid (SA) as a biofungicide by using the highly pathogenic Fusarium oxysporum as a model system. The results showed that SA could inhibit key targets of the pathogen, modify the metabolic activity within pathogen cells, and induce pathogen cell death. This research provides insights into the application of SA in controlling various fungal diseases by targeting the SNF1-TORC1 pathway of pathogens.
JOURNAL OF ADVANCED RESEARCH
(2022)
Article
Plant Sciences
Jiming Li, Like Fokkens, Martijn Rep
Summary: By comparing the pathogenicity chromosomes of Fusarium oxysporum f. sp. radicis-cucumerinum and F. oxysporum f. sp. melonis, researchers identified a candidate gene that may be responsible for the difference in host range between these two formae speciales.
MOLECULAR PLANT PATHOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Anuranjan Singh Rathore, Krishna Kant Gupta, Jeyabharathy Chandrasekaran, Sam Aldrin Chandran
Summary: This study aimed to elucidate the structure of SIX1, a pathogenicity factor of Fusarium oxysporum f. sp. Lycopersici (FOL), and identified a potential small-molecule inhibitor, 4-[[2-(3-methoxyphenoxy)acetyl]amino] benzamide, for FOL infection.
MOLECULAR DIVERSITY
(2023)
Article
Microbiology
Claudette Dewing, Magrieta A. Van der Nest, Quentin C. Santana, Robert H. Proctor, Brenda D. Wingfield, Emma T. Steenkamp, Lieschen De Vos
Summary: This study used comparative genomics to elucidate the mechanisms underlying the ability of grass-associated and pine-associated Fusarium species to colonize their respective plant hosts. The results showed that the genes associated with host range originated and were retained through various mechanisms during the evolution of Fusarium. These host-range-associated genes tended to be located towards the subtelomeric regions of chromosomes.
Article
Microbiology
Houlin Yu, He Yang, Sajeet Haridas, Richard D. Hayes, Hunter Lynch, Sawyer Andersen, Madison Newman, Gengtan Li, Domingo Martinez-Soto, Shira Milo-Cochavi, Dilay Hazal Ayhan, Yong Zhang, Igor V. Grigoriev, Li-Jun Ma
Summary: This study investigates the global transcription factor profiles (TFomes) and their potential roles in coordinating core and accessory chromosome functions to achieve host-specific interactions in FOSC. The sizes of TFomes are positively correlated with the proteomes of an organism, and FOSC TFomes are larger than other fungal genomes. Functional characterization of these TFs could enhance our understanding of transcriptional regulation involved in FOSC cross-kingdom interactions and identify targets to combat diverse diseases caused by this group of fungal pathogens.