Long noncoding RNA ‐dependent methylation of nonhistone proteins

Long non‐coding RNAs in development and disease: conservation to mechanisms

(2020) Ioannis Tsagakis et al.   JOURNAL OF PATHOLOGY

TEAD4 modulated LncRNA MNX1-AS1 contributes to gastric cancer progression partly through suppressing BTG2 and activating BCL2

(2020) You Shuai et al.   Molecular Cancer

LNCPILA, a novel PRMT1 interacting long noncoding RNA, promotes osteoarthritis cartilage degradation via positively regulating the NF-KB pathway

(2020) S. Tang et al.   OSTEOARTHRITIS AND CARTILAGE

Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2

(2020) Chunqing Wang et al.   Nature Communications

Long Non-Coding RNA MNX1-AS1 Promotes Progression of Triple Negative Breast Cancer by Enhancing Phosphorylation of Stat3

(2020) Junhua Li et al.   Frontiers in Oncology

The mechanisms of lncRNA Tug1 in islet dysfunction in a mouse model of intrauterine growth retardation

(2020) Yihui Li et al.   CELL BIOCHEMISTRY AND FUNCTION

Long non-coding RNAs: the tentacles of chromatin remodeler complexes

(2020) Bernadette Neve et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin

(2020) Yaohua Zhang et al.   NATURE CELL BIOLOGY

AKT-induced lncRNA VAL promotes EMT-independent metastasis through diminishing Trim16-dependent Vimentin degradation

(2020) Han Tian et al.   Nature Communications

c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis

(2020) Yu Chen Feng et al.   Nature Communications

Gene regulation by long non-coding RNAs and its biological functions

(2020) Luisa Statello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long noncoding RNA MNX1-AS1 contributes to lung cancer progression through the miR-527/BRF2 pathway

(2019) Haibo Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MNX1-AS1 is a functional oncogene that induces EMT and activates the AKT/mTOR pathway and MNX1 in breast cancer

(2019) Yue Cheng et al.   Cancer Management and Research

ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles

(2019) Haiyan An et al.   Acta Neuropathologica Communications

The long noncoding RNA ST7-AS1 promotes laryngeal squamous cell carcinoma by stabilizing CARM1

(2019) Haiping Qin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long non-coding RNA MNX1-AS1 promotes hepatocellular carcinoma proliferation and invasion through targeting miR-218-5p/COMMD8 axis

(2019) Degang Ji et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

lncRNA TUG1 Promotes Cisplatin Resistance by Regulating CCND2 via Epigenetically Silencing miR-194-5p in Bladder Cancer

(2019) Gan Yu et al.   Molecular Therapy-Nucleic Acids

LINC00184 silencing inhibits glycolysis and restores mitochondrial oxidative phosphorylation in esophageal cancer through demethylation of PTEN

(2019) Weihao Li et al.   EBioMedicine

The Hippo Signaling Pathway in Development and Disease

(2019) Yonggang Zheng et al.   DEVELOPMENTAL CELL

Altered levels of hsromega lncRNAs further enhance Ras signaling during ectopically activated Ras induced R7 differentiation in Drosophila

(2019) Mukulika Ray et al.   GENE EXPRESSION PATTERNS

The lncRNA hsrω regulates arginine dimethylation of FUS to cause its proteasomal degradation in Drosophila

(2019) Luca Lo Piccolo et al.   JOURNAL OF CELL SCIENCE

Regulation of gene expression by cis-acting long non-coding RNAs

(2019) Noa Gil et al.   NATURE REVIEWS GENETICS

Long noncoding RNAs: Undeciphered cellular codes encrypting keys of colorectal cancer pathogenesis

(2018) Taewan Kim et al.   CANCER LETTERS

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

(2018) Seema Qamar et al.   CELL

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer

(2018) Kuo-Wang Tsai et al.   Molecular Cancer

Towards a complete map of the human long non-coding RNA transcriptome

(2018) Barbara Uszczynska-Ratajczak et al.   NATURE REVIEWS GENETICS

LncRNA MNX1-AS1 promotes glioblastoma progression through inhibition of miR-4443

(2018) Yan Gao et al.   ONCOLOGY RESEARCH

The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma

(2018) Zhe Li et al.   Nature Communications

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy

(2018) Maneka Chitiprolu et al.   Nature Communications

The LINC01138 interacts with PRMT5 to promote SREBP1-mediated lipid desaturation and cell growth in clear cell renal cell carcinoma

(2018) Xi Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Zhenbao Pill reduces Treg cell proportion in acute spinal cord injury rats by regulating TUG1/miR-214/HSP27 axis

(2018) Yongxiong He et al.   BIOSCIENCE REPORTS

Identification of potential prognostic TF‐associated lncRNAs for predicting survival in ovarian cancer

(2018) Qiuyan Guo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

E2F1-mediated MNX1-AS1-miR-218-5p-SEC61A1 feedback loop contributes to the progression of colon adenocarcinoma

(2018) Yaqun Ye et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

LncRNA MNX1-AS1 promotes the progression of cervical cancer through activating MAPK pathway

(2018) Xiang Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

RNAi of arcRNA hsrω affects sub-cellular localization of Drosophila FUS to drive neurodiseases

(2017) Luca Lo Piccolo et al.   EXPERIMENTAL NEUROLOGY

EZH2-mediated α-actin methylation needs lncRNA TUG1, and promotes the cortex cytoskeleton formation in VSMCs

(2017) Rong Chen et al.   GENE

A ROR1–HER3–lncRNA signalling axis modulates the Hippo–YAP pathway to regulate bone metastasis

(2017) Chunlai Li et al.   NATURE CELL BIOLOGY

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation

(2017) Ruibing Chen et al.   NUCLEIC ACIDS RESEARCH

LINC00052 Promotes Gastric Cancer Cell Proliferation and Metastasis via Activating the Wnt/β-Catenin Signaling Pathway

(2017) Yuqiang Shan et al.   ONCOLOGY RESEARCH

The Dimensions, Dynamics, and Relevance of the Mammalian Noncoding Transcriptome

(2017) Ira W. Deveson et al.   TRENDS IN GENETICS

LINC00052 upregulates EPB41L3 to inhibit migration and invasion of hepatocellular carcinoma by binding miR-452-5p

(2017) Liying Zhu et al.   Oncotarget

New perspectives on telomerase RNA structure and function

(2017) Cherie Musgrove et al.   Wiley Interdisciplinary Reviews-RNA

FUS toxicity is rescued by the modulation of lncRNA hsrω expression in Drosophila melanogaster

(2017) Luca Lo Piccolo et al.   Scientific Reports

Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins

(2016) Sungyul Lee et al.   CELL

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

(2016) Jelena Scekic‐Zahirovic et al.   EMBO JOURNAL

Unique features of long non-coding RNA biogenesis and function

(2016) Jeffrey J. Quinn et al.   NATURE REVIEWS GENETICS

lnc-β-Catm elicits EZH2-dependent β-catenin stabilization and sustains liver CSC self-renewal

(2016) Pingping Zhu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function

(2016) Aarti Sharma et al.   Nature Communications

Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment

(2016) Keisuke Katsushima et al.   Nature Communications

A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells

(2016) Ailone Tichon et al.   Nature Communications

lnc-β-Catm elicits EZH2-dependent β-catenin stabilization and sustains liver CSC self-renewal

(2016) Pingping Zhu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

LINC00052 regulates the expression of NTRK3 by miR-128 and miR-485-3p to strengthen HCC cells invasion and migration

(2016) Dongmei Xiong et al.   Oncotarget

HER3 and LINC00052 interplay promotes tumor growth in breast cancer

(2016) Ahmad Salameh et al.   Oncotarget

Identification of androgen-responsive lncRNAs as diagnostic and prognostic markers for prostate cancer

(2016) Xuechao Wan et al.   Oncotarget

Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2

(2015) Ming-De Huang et al.   Molecular Cancer

Technologies to probe functions and mechanisms of long noncoding RNAs

(2015) Ci Chu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Technologies to probe functions and mechanisms of long noncoding RNAs

(2015) Ci Chu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Principles of Long Noncoding RNA Evolution Derived from Direct Comparison of Transcriptomes in 17 Species

(2015) Hadas Hezroni et al.   Cell Reports

An Evolutionarily Conserved Long Noncoding RNA TUNA Controls Pluripotency and Neural Lineage Commitment

(2014) Nianwei Lin et al.   MOLECULAR CELL

lncRNASNP: a database of SNPs in lncRNAs and their potential functions in human and mouse

(2014) Jing Gong et al.   NUCLEIC ACIDS RESEARCH

The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation

(2014) P. Wang et al.   SCIENCE

P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression

(2014) E-b Zhang et al.   Cell Death & Disease

Non-coding RNA: a new frontier in regulatory biology

(2014) Xiang-Dong Fu   National Science Review

lincRNAs: Genomics, Evolution, and Mechanisms

(2013) Igor Ulitsky et al.   CELL

Regulation of the DNA Damage Response by an Inducible Long Noncoding RNA

(2013) A. Schmitt et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Transportin 1 accumulates in FUS inclusions in adult-onset ALS withoutFUSmutation

(2013) R. Takeuchi et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Widespread purifying selection on RNA structure in mammals

(2013) Martin A. Smith et al.   NUCLEIC ACIDS RESEARCH

Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination

(2013) Je-Hyun Yoon et al.   Nature Communications

Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations

(2012) Manuela Neumann et al.   ACTA NEUROPATHOLOGICA

Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS

(2012) Dorothee Dormann et al.   EMBO JOURNAL

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Long non-coding RNAs coordinate cellular responses to stress

(2012) Subhash C. Lakhotia   Wiley Interdisciplinary Reviews-RNA

Conserved Function of lincRNAs in Vertebrate Embryonic Development despite Rapid Sequence Evolution

(2011) Igor Ulitsky et al.   CELL

RNA templating the epigenome

(2011) Robert C. Spitale et al.   Epigenetics

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Long non-coding RNAs in Huntington's disease neurodegeneration

(2011) Rory Johnson   NEUROBIOLOGY OF DISEASE

Long noncoding RNAs and human disease

(2011) Orly Wapinski et al.   TRENDS IN CELL BIOLOGY

Long Noncoding RNAs with Enhancer-like Function in Human Cells

(2010) Ulf Andersson Ørom et al.   CELL

Improved Activities of CREB Binding Protein, Heterogeneous Nuclear Ribonucleoproteins and Proteasome Following Downregulation of Noncoding hsr  Transcripts Help Suppress Poly(Q) Pathogenesis in Fly Models

(2010) M. Mallik et al.   GENETICS

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

RNAi for the large non-coding hsrω transcripts suppresses polyglutamine pathogenesis inDrosophilamodels

(2010) Moushami Mallik et al.   RNA Biology

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS