Aerobic glycolysis supports hepatitis B virus protein synthesis through interaction between viral surface antigen and pyruvate kinase isoform M2

Drugs in the Pipeline for HBV

(2019) Uri Lopatin   Clinics in Liver Disease

Viral hijacking of cellular metabolism

(2019) Shivani K. Thaker et al.   BMC BIOLOGY

Hijacking the Supplies: Metabolism as a Novel Facet of Virus-Host Interaction

(2019) Katharina A. Mayer et al.   Frontiers in Immunology

Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis

(2018) Tian-Neng Li et al.   JOURNAL OF PATHOLOGY

Hepatitis B virus large surface protein is priming for hepatocellular carcinoma development via induction of cytokinesis failure

(2018) Julian Musa et al.   JOURNAL OF PATHOLOGY

Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development

(2018) Jianming Hu et al.   GASTROENTEROLOGY

RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg

(2017) Christine I. Wooddell et al.   Science Translational Medicine

Antibody-mediated immunotherapy against chronic hepatitis B virus infection

(2017) Ying Gao et al.   Human Vaccines & Immunotherapeutics

PKM2, cancer metabolism, and the road ahead

(2016) Talya L Dayton et al.   EMBO REPORTS

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hepatitis B virus PreS2-mutant large surface antigen activates store-operated calcium entry and promotes chromosome instability

(2016) Tim Ting-Chung Yen et al.   Oncotarget

HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B

(2015) Michael Nassal   GUT

Hepatitis B virus infection

(2014) Christian Trépo et al.   LANCET

Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP

(2013) Masashi Iwamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1 -mediated glucose metabolism

(2013) H.-J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyruvate Kinase M2: Multiple Faces for Conferring Benefits on Cancer Cells

(2012) M. Tamada et al.   CLINICAL CANCER RESEARCH

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

(2012) Dimitrios Anastasiou et al.   Nature Chemical Biology

Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection

(2011) Antonio Bertoletti et al.   GUT

A longitudinal study on the natural history of serum hepatitis B surface antigen changes in chronic hepatitis B

(2010) Henry Lik-Yuen Chan et al.   HEPATOLOGY

Sequential control of hepatitis B virus in a mouse model of acute, self-resolving hepatitis B

(2010) M. John von Freyend et al.   JOURNAL OF VIRAL HEPATITIS

Metabolic Factors and Risk of Hepatocellular Carcinoma by Chronic Hepatitis B/C Infection: A Follow-up Study in Taiwan

(2008) Chi–Ling Chen et al.   GASTROENTEROLOGY