Review
Geriatrics & Gerontology
Zihan Yin, Jun Zhou, Manze Xia, Zhenghong Chen, Yaqin Li, Xinyue Zhang, Xiang Li, Hang Yan, Lu Wang, Mingsheng Sun, Ling Zhao, Fanrong Liang, Ziwen Wang
Summary: Acupuncture has shown effectiveness in improving cognitive function in patients with mild cognitive impairment (MCI). However, previous studies have mainly focused on the cognitive effects and the neurological effects of acupuncture are relatively unclear. This systematic review summarized existing studies using different brain imaging techniques and found that acupuncture may induce brain alterations in MCI patients, particularly in the cingulate cortex, prefrontal cortex, and hippocampus. The effects of acupuncture on MCI may be associated with the regulation of the default mode network, central executive network, and salience network.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Review
Cell Biology
Xiuwen Li, Xiaojie Wang, Lan Guo, Keying Wu, Li Wang, Lu Rao, Xinjian Liu, Chenyao Kang, Bin Jiang, Qian Li, Huling Li, Fenfen He, Ciyong Lu
Summary: This systematic review and meta-analysis examined the association between lipocalin-2 (LCN2) and mild cognitive impairment (MCI) and dementia. The results showed no significant difference in peripheral blood LCN2 levels between Alzheimer's disease (AD), MCI, and control groups. However, cerebrospinal fluid (CSF) LCN2 levels were higher in vascular dementia (VaD) patients compared to controls and AD patients. LCN2 was increased in AD-related brain areas and cells, as well as in infarct-related brain areas and cells in mixed dementia (MD).
AGEING RESEARCH REVIEWS
(2023)
Review
Psychology, Multidisciplinary
Alexandra Wolf, Kornkanok Tripanpitak, Satoshi Umeda, Mihoko Otake-Matsuura
Summary: Mild cognitive impairment (MCI) is a transitional zone between normal cognition and dementia, and has become a novel topic in clinical research. Early detection is crucial but logistically challenging, and technological advancements in cognitive scoring methodologies are needed. Non-invasive eye-tracking-based paradigms may contribute to early AD detection, but further longitudinal investigations are necessary for clinical applications.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Medicine, General & Internal
Zihan Ding, Tsz-Lok Lee, Agnes S. Chan
Summary: The current systematic review aims to identify digital cognitive biomarkers from computerized tests for detecting dementia and mild cognitive impairment (MCI), and evaluates their diagnostic performance. Results showed that digital cognitive biomarkers achieved comparable or better diagnostic performance than traditional tests, and have the potential to be sensitive markers for MCI and dementia.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Clinical Neurology
Zihan Yin, Yaqin Li, Cheng Jiang, Manze Xia, Zhenghong Chen, Xinyue Zhang, Ling Zhao, Fanrong Liang
Summary: This study aimed to evaluate the effect of acupuncture on patients with mild cognitive impairment (MCI). The analysis of 11 randomized controlled trials (RCTs) showed that acupuncture has a positive effect on improving overall cognitive function (OCF) in patients with MCI, but the improvement in memory function (MF) and activities of daily living (ADLs) is inconclusive.
FRONTIERS IN NEUROLOGY
(2023)
Review
Cell Biology
Michael K. Yeung, Anson Kwok-yun Chau, Jason Yin-chuen Chiu, Jay Tsz-lok Shek, Jody Po-yi Leung, Toby Chun-ho Wong
Summary: The study found significant differences in neuroimaging abnormalities between amnestic mild cognitive impairment (aMCI) and nonamnestic mild cognitive impairment (naMCI), with aMCI showing more and more significant abnormalities, while naMCI showing more limited abnormalities, with shared features but unique neuroimaging abnormalities in aMCI.
AGEING RESEARCH REVIEWS
(2022)
Review
Endocrinology & Metabolism
Rachel Heutz, Jurgen Claassen, Sanne Feiner, Aaron Davies, Dewakar Gurung, Ronney B. Panerai, Rianne de Heus, Lucy C. Beishon
Summary: Dynamic cerebral autoregulation (dCA) is a key mechanism that regulates cerebral blood flow in response to transient changes in blood pressure. The literature remains conflicted on whether dCA is altered in Alzheimer's disease (AD) and mild cognitive impairment (MCI). A qualitative synthesis of eight studies suggests no significant difference in dCA parameters for spontaneous fluctuations between AD, MCI, and healthy controls. Limited data on induced fluctuations indicate preserved or possibly better autoregulatory functioning in AD and MCI compared to controls. Further research is needed to investigate dCA in dementia with induced fluctuations controlling for changes in end-tidal carbon dioxide.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2023)
Review
Geriatrics & Gerontology
Zhi Cai, Yanling Ma, Lei Li, Gui-Zhi Lu
Summary: This study conducted a systematic review and meta-analysis to assess the effects of exergaming interventions on cognitive function, physical performance, and quality of life in patients with MCI and dementia. The results showed significant improvements in cognitive function and physical performance, but no significant improvements in activities of daily living, instrumental activity of daily living, and quality of life.
Review
Geriatrics & Gerontology
Luis Carlos Venegas-Sanabria, Vicente Martinez-Vizcaino, Ivan Cavero-Redondo, Diego Andres Chavarro-Carvajal, Carlos Alberto Cano-Gutierrez, Celia Alvarez-Bueno
Summary: Physical activity has a positive effect on cognition in people with dementia and mild cognitive impairment, especially in terms of global cognition. Positive effects were also shown on executive function and memory, confirming the relevance of physical activity in the treatment of cognitive impairment.
AGING & MENTAL HEALTH
(2021)
Review
Chemistry, Medicinal
Nafiseh Ghassab-Abdollahi, Khorshid Mobasseri, Ali Dehghani Ahmadabad, Haidar Nadrian, Mojgan Mirghafourvand
Summary: Research shows that Huperzine A has beneficial effects on Alzheimer's disease, but its effects on vascular dementia and mild cognitive impairment are unclear. Limited evidence supports its effectiveness on quality of life and global clinical assessment.
PHYTOTHERAPY RESEARCH
(2021)
Review
Medicine, General & Internal
Ilaria Corbo, Giulia Marselli, Valerio Di Ciero, Maria Casagrande
Summary: Cognitive reserve (CR) is the ability to adapt and compensate for brain damage or disease. This systematic literature review examined the role of CR in preventing Mild Cognitive Impairment (MCI) and found that high CR is significantly associated with a reduced risk of MCI. The review also confirmed a positive relationship between CR and cognitive functioning in both MCI and healthy individuals.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Geriatrics & Gerontology
Lin Wang, Tie Zhao, Xu Zhu, Qinghua Jiang
Summary: A meta-analysis showed that lower blood carotenoid levels may be a risk factor for dementia and mild cognitive impairment (MCI).
Review
Nursing
Dandan Xue, Polly W. C. Li, Doris S. F. Yu, Rose S. Y. Lin
Summary: This review compares the effects of combined exercise and cognitive interventions with single exercise or cognitive interventions, as well as control groups, on cognitive, psychological, functional outcomes, and health-related quality of life in adults with mild cognitive impairment and dementia. The results show that combined interventions are superior to exercise in improving response inhibition, working memory, and delayed recall, but not superior to cognitive interventions in all outcomes. Combined interventions are superior to active/passive controls in improving global cognition, response inhibition, immediate recall, delayed recall, category fluency, processing speed, and visuospatial ability. The influence of clinical severity of dementia, combination format, mode of delivery, training duration, and types of control were not detected. The network meta-analysis results indicate that the optimal intervention components vary across different outcomes, with multimodal exercise combining cognitive training demonstrating the greatest effects in improving global cognition.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2023)
Review
Cell Biology
Georgia Bell, Timothy Singham, Rob Saunders, Amber John, Joshua Stott
Summary: Understanding the association between positive psychological factors and the risk of dementia is important for dementia prevention interventions. This review found that purpose in life was significantly associated with a reduced risk of dementia, while positive affect showed no significant association. Further research is needed to explore the association between other positive psychological factors and dementia risk.
AGEING RESEARCH REVIEWS
(2022)
Review
Biochemistry & Molecular Biology
Kyoungjoo Cho
Summary: Cognitive impairment is a serious condition associated with aging and disruption of inflammation and innate immunity. Recent studies have shown that the innate immune system is prevalent in patients with Alzheimer's disease, and peripheral neutrophil markers can predict a decline in cognitive function in patients with mild cognitive impairment. Furthermore, altered levels of pro-inflammatory interleukins have been reported in patients with mild cognitive impairment, potentially playing a role in the progression from early cognitive impairment to dementia.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Integrative & Complementary Medicine
Meixuan Li, Junqiang Niu, Peijing Yan, Liang Yao, Wenbo He, Meng Wang, Huijuan Li, Liujiao Cao, Xiuxia Li, Xiue Shi, Xingrong Liu, Kehu Yang
COMPLEMENTARY THERAPIES IN MEDICINE
(2020)
Review
Obstetrics & Gynecology
Meng Wang, Wenbo He, Meixuan Li, Fuyun Li, Lili Jiang, Jiabin Wang, Hui Wang, Xudong Liu, Kehu Yang, Jie Qiu
HYPERTENSION IN PREGNANCY
(2020)
Review
Public, Environmental & Occupational Health
Wenbo He, Lili Jiang, Xiaojie Ge, Jiaxin Ye, Na Yang, Meixuan Li, Meng Wang, Xuemei Han
PSYCHOLOGY HEALTH & MEDICINE
(2020)
Review
Pediatrics
Li-Li Jiang, Yin-Yan Gao, Wen-Bo He, Ting Gan, Hou-Qian Shan, Xue-Mei Han
WORLD JOURNAL OF PEDIATRICS
(2020)
Article
Public, Environmental & Occupational Health
Yan Wu, Wenbo He, Sen Chen, Yu Xiao, Wei Zhang
Summary: The study found a significant positive correlation between risk perception of medical postgraduates and their adaptability, confidence, and risk response behavior. Risk perception not only directly predicted adaptability, but also influenced adaptability through three indirect pathways.
PSYCHOLOGY HEALTH & MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Wenbo He, Meixuan Li, Jiaxin Ye, Yanfei Shen, Yongwen Cao, Sheng Zhou, Xuemei Han
Summary: The purpose of this study was to explore the correlation between the perception of high performance work system (P-HPWS) and job burnout of nurses, and to examine the mediating role of regulatory emotional self-efficacy (RES). The results showed a significant negative correlation between P-HPWS and job burnout, with RES mediating the relationship. These findings highlight the importance of P-HPWS in alleviating job burnout and suggest implementing and improving the system as a way to enhance management.
PSYCHOLOGY HEALTH & MEDICINE
(2023)
Review
Integrative & Complementary Medicine
Yang-Hao-Tian Wu, Wen-Bo He, Yin-Yan Gao, Xue-Mei Han
Summary: The study found significant improvements in sleep quality for older adults through both traditional Chinese exercises (TCEs) and general aerobic exercises (GAEs), including subjective sleep quality, sleep latency, and sleep duration. Subgroup analysis revealed that TCEs showed superiority after 12 weeks, and Qigong had a greater intervention effect for improving sleep quality compared to Tai Chi. Meta-regression analysis did not identify specific covariables accounting for overall heterogeneity.
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2021)
Review
Gerontology
Yinyan Gao, Yancong Chen, Mingyue Hu, Ting Gan, Xuemei Sun, Zixuan Zhang, Wenbo He, Irene X. Y. Wu
Summary: Several prediction models for frailty in older adults have been published, but their characteristics and methodological quality are unclear. This review aims to summarize and critically appraise the prediction models. The included models showed good predictive discrimination, but most studies were assessed as high risk of bias and poor reporting quality was frequently observed. Few mature prediction models can be used in practice, and researchers should focus on external validation and improving the quality both in methodology and reporting.
JOURNAL OF APPLIED GERONTOLOGY
(2022)
Article
Health Care Sciences & Services
Liujiao Cao, Liang Yao, Wenbo He, Liangying Hou, Zhe Yin, Dan Wang, Ka Li
Summary: This study aimed to assess the methodological quality of ERAS guidelines using the AGREE II instrument and determine the concordance of different recommendations. The results showed that the methodological quality of ERAS guidelines varied and was generally low.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Article
Geriatrics & Gerontology
Wenbo He, Liujiao Cao, Rui Liu, Yi Wu, Wei Zhang
Summary: This study examined the use of Internet/health information technology (HIT) among older adults with physical multi-morbidity. It found that the use of Internet and HIT among this population is still far from the recommended target. The study also identified various sociodemographic factors associated with Internet and HIT use, emphasizing the importance of considering these factors in health education interventions.
Article
Multidisciplinary Sciences
Jiu-Hong You, Jun-Liang Jiang, Wen-Bo He, Hui Maa, Mei Zhou, Xin-Xin Chen, Qiao-Ling Liu, Cheng Huang
Summary: This study conducted a systematic review and meta-analysis to investigate the adjunctive role of hyperbaric oxygen therapy (HBOT) in treating inflammatory bowel disease (IBD) and lowering its recurrence rate. The findings suggest that HBOT may be an effective and safe treatment for IBD, particularly in ulcerative colitis patients. Further research is needed to determine the optimal protocol for HBOT in IBD treatment.
Article
Public, Environmental & Occupational Health
Wenbo He, Peiyi Li, Yinyan Gao, Jiuhong You, Jiangeng Chang, Xing Qu, Wei Zhang
Summary: This study examined the mediating effects of internet use and social participation on the relationship between self-reported visual impairment (VI) and depression. The results showed that internet use and social participation played important roles in mitigating the effects of VI on depression.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Jiawen Zhang, Wenbo He, Jingwen Jiang, Xiaolei Luo, Gaiyun Li, Yilun Li, Mingfeng Ding, Yajie Zhang, Yanfei Shen, Yongwen Cao, Sheng Zhou, Xuemei Han
Summary: This study aimed to explore the correlation between the perception of the high-performance work system (P-HPWS) and job satisfaction of medical staff in public hospitals, as well as the mediating effect of self-efficacy. A survey was conducted on working doctors and nurses in five tertiary public hospitals in China, with a total of 520 participants. The results showed a significant positive correlation between P-HPWS and job satisfaction, with self-efficacy playing a mediating role. This finding highlights the importance of improving P-HPWS and self-efficacy to enhance job satisfaction among medical staff, and suggests that hospitals can improve their management systems accordingly.
PSYCHOLOGY HEALTH & MEDICINE
(2023)
Review
Medicine, General & Internal
Wenbo He, Meixuan Li, Liujiao Cao, Rui Liu, Jiuhong You, Fangyuan Jing, Jiawen Zhang, Wei Zhang, Mengling Feng
Summary: Objective Value-based healthcare (VBHC) puts patient outcomes at the center of the healthcare process while optimizing the use of hospital resources. This scoping review summarizes how VBHC has been represented in theory and practice, its application in assessing hospital performance, and its implementation effectiveness. The results indicate that current healthcare performance assessment is beginning to focus on implementing VBHC as an integrated strategy, and future research should further clarify the reliability of metrics and their association with evaluation outcomes, and consider the effective integration of clinical outcomes and patient-reported outcomes.
JOURNAL OF EVIDENCE BASED MEDICINE
(2023)