A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection

A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation

(2020) Jin Rui Liang et al.   CELL

Viral hijacking of the TENT4–ZCCHC14 complex protects viral RNAs via mixed tailing

(2020) Dongwan Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus

(2020) Anshuman Das et al.   Nature Microbiology

Ribosomal protein RPL26 is the principal target of UFMylation

(2019) Christopher P. Walczak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses

(2019) Efraín E Rivera-Serrano et al.   eLife

Enterovirus pathogenesis requires the host methyltransferase SETD3

(2019) Jonathan Diep et al.   Nature Microbiology

UFMylation of RPL26 links translocation-associated quality control to endoplasmic reticulum protein homeostasis

(2019) Lihui Wang et al.   CELL RESEARCH

The UFMylation System in Proteostasis and Beyond

(2019) Yannis Gerakis et al.   TRENDS IN CELL BIOLOGY

A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production

(2019) Anastasia Hyrina et al.   Cell Reports

A novel orally available small molecule that inhibits hepatitis B virus expression

(2018) Henrik Mueller et al.   JOURNAL OF HEPATOLOGY

Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation

(2018) Jaechul Lim et al.   SCIENCE

STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection

(2018) Siyuan Ding et al.   Nature Communications

Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication

(2018) Julianna Han et al.   Cell Reports

Hepatitis A Virus Genome Organization and Replication Strategy

(2018) Kevin L. McKnight et al.   Cold Spring Harbor Perspectives in Medicine

Globalization and the Changing Epidemiology of Hepatitis A Virus

(2018) Kathryn H. Jacobsen   Cold Spring Harbor Perspectives in Medicine

Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels

(2018) Chunkyu Ko et al.   JOURNAL OF HEPATOLOGY

Redundant late domain functions of tandem VP2 YPX3L motifs in nonlytic cellular egress of quasi-enveloped hepatitis A virus

(2018) Olga González-López et al.   JOURNAL OF VIROLOGY

The Functional Role of the 3′ Untranslated Region and Poly(A) Tail of Duck Hepatitis A Virus Type 1 in Viral Replication and Regulation of IRES-Mediated Translation

(2018) Jun-Hao Chen et al.   Frontiers in Microbiology

PAPD5/7 are novel host factors that are required for Hepatitis B virus RNA stabilization

(2018) Henrik Mueller et al.   HEPATOLOGY

Terminal nucleotidyl transferases (TENTs) in mammalian RNA metabolism

(2018) Zbigniew Warkocki et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Trans-kingdom mimicry underlies ribosome customization by a poxvirus kinase

(2017) Sujata Jha et al.   NATURE

Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism

(2017) Jihae Shin et al.   NUCLEIC ACIDS RESEARCH

Cellular cap-binding protein, eIF4E, promotes picornavirus genome restructuring and translation

(2017) Brian C. Avanzino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TIM1 (HAVCR1) Is Not Essential for Cellular Entry of Either Quasi-enveloped or Naked Hepatitis A Virions

(2017) Anshuman Das et al.   mBio

A role for glycolipid biosynthesis in severe fever with thrombocytopenia syndrome virus entry

(2017) Mary Jane Drake et al.   PLoS Pathogens

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

(2016) Rong Zhang et al.   NATURE

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

(2016) Caleb D. Marceau et al.   NATURE

Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

(2016) Laura Broutier et al.   Nature Protocols

Enterovirus D68 receptor requirements unveiled by haploid genetics

(2016) Jim Baggen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

(2015) Meritxell Huch et al.   CELL

RACK1 Controls IRES-Mediated Translation of Viruses

(2014) Karim Majzoub et al.   CELL

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

The cytoplasmic poly(A) polymerases GLD-2 and GLD-4 promote general gene expression via distinct mechanisms

(2014) Marco Nousch et al.   NUCLEIC ACIDS RESEARCH

Suppression of La Antigen Exerts Potential Antiviral Effects against Hepatitis A Virus

(2014) Xia Jiang et al.   PLoS One

PAPD5-mediated 3' adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease

(2014) J. Boele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ER Complex of ODR-4 and ODR-8/Ufm1 Specific Protease 2 Promotes GPCR Maturation by a Ufm1-Independent Mechanism

(2014) Changchun Chen et al.   PLoS Genetics

Naked Viruses That Aren't Always Naked: Quasi-Enveloped Agents of Acute Hepatitis

(2014) Zongdi Feng et al.   Annual Review of Virology

Virus Budding and the ESCRT Pathway

(2013) Jörg Votteler et al.   Cell Host & Microbe

Structural Features of a Picornavirus Polymerase Involved in the Polyadenylation of Viral RNA

(2013) B. J. Kempf et al.   JOURNAL OF VIROLOGY

A pathogenic picornavirus acquires an envelope by hijacking cellular membranes

(2013) Zongdi Feng et al.   NATURE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Adaptation of a Genotype 3 Hepatitis E Virus to Efficient Growth in Cell Culture Depends on an Inserted Human Gene Segment Acquired by Recombination

(2012) P. Shukla et al.   JOURNAL OF VIROLOGY

Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming

(2012) H. Berndt et al.   RNA

Structure of Ubiquitin-fold Modifier 1-specific Protease UfSP2

(2011) Byung Hak Ha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction Profiling Identifies the Human Nuclear Exosome Targeting Complex

(2011) Michal Lubas et al.   MOLECULAR CELL

PAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif

(2011) C. Rammelt et al.   RNA

Mutations in VP2 and VP1 capsid proteins increase infectivity and mouse lethality of enterovirus 71 by virus binding and RNA accumulation enhancement

(2011) Sheng-Wen Huang et al.   VIROLOGY

Polyadenylation and degradation of incomplete RNA polymerase I transcripts in mammalian cells

(2010) Natalia Shcherbik et al.   EMBO REPORTS

A Novel C53/LZAP-interacting Protein Regulates Stability of C53/LZAP and DDRGK Domain-containing Protein 1 (DDRGK1) and Modulates NF-κB Signaling

(2010) Jianchun Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Poly(A) at the 3' End of Positive-Strand RNA and VPg-Linked Poly(U) at the 5' End of Negative-Strand RNA Are Reciprocal Templates during Replication of Poliovirus RNA

(2010) B. P. Steil et al.   JOURNAL OF VIROLOGY

Structure and function of the polymerase core of TRAMP, a RNA surveillance complex

(2010) S. Hamill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs

(2009) D. M. Landry et al.   GENES & DEVELOPMENT

A Novel Type of E3 Ligase for the Ufm1 Conjugation System

(2009) Kanako Tatsumi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

(2009) Eric Campeau et al.   PLoS One

Highly parallel identification of essential genes in cancer cells

(2008) B. Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA