The AD tau core spontaneously self-assembles and recruits full-length tau to filaments
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The AD tau core spontaneously self-assembles and recruits full-length tau to filaments
Authors
Keywords
tau, aggregation, filament core, neurofibrillary tangles, Alzheimer's disease, tauopathy, real-time quaking-induced conversion, biomarker, corticobasal degeneration, Pick's disease
Journal
Cell Reports
Volume 34, Issue 11, Pages 108843
Publisher
Elsevier BV
Online
2021-03-19
DOI
10.1016/j.celrep.2021.108843
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
- (2020) Tamta Arakhamia et al. CELL
- Novel tau filament fold in corticobasal degeneration
- (2020) Wenjuan Zhang et al. NATURE
- LRP1 is a master regulator of tau uptake and spread
- (2020) Jennifer N. Rauch et al. NATURE
- FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments
- (2020) Senthilvelrajan Kaniyappan et al. Molecular Neurodegeneration
- Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease
- (2020) Simon Dujardin et al. NATURE MEDICINE
- Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
- (2019) Benjamin Falcon et al. NATURE
- Ultrasensitive Detection of Aggregated α-Synuclein in Glial Cells, Human Cerebrospinal Fluid, and Brain Tissue Using the RT-QuIC Assay: New High-Throughput Neuroimmune Biomarker Assay for Parkinsonian Disorders
- (2019) Sireesha Manne et al. Journal of Neuroimmune Pharmacology
- Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzheimer’s Disease
- (2019) Nicolas R. Barthélemy et al. Frontiers in Aging Neuroscience
- Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases
- (2019) Wenjuan Zhang et al. eLife
- Cerebrospinal fluid from Alzheimer’s disease patients promotes tau aggregation in transgenic mice
- (2019) Zhiva Skachokova et al. Acta Neuropathologica Communications
- Distinct Conformations, Aggregation and Cellular Internalization of Different Tau Strains
- (2019) Thomas K. Karikari et al. Frontiers in Cellular Neuroscience
- Cortical tau deposition follows patterns of entorhinal functional connectivity in aging
- (2019) Jenna N Adams et al. eLife
- 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration
- (2019) Eri Saijo et al. ACTA NEUROPATHOLOGICA
- α‐Synuclein real‐time quaking‐induced conversion in the submandibular glands of Parkinson's disease patients
- (2019) Sireesha Manne et al. MOVEMENT DISORDERS
- Heparin-induced tau filaments are structurally heterogeneous and differ from Alzheimer's disease filaments
- (2018) Yann Fichou et al. CHEMICAL COMMUNICATIONS
- Tau protein liquid–liquid phase separation can initiate tau aggregation
- (2018) Susanne Wegmann et al. EMBO JOURNAL
- Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers
- (2018) James P. Quinn et al. JOURNAL OF ALZHEIMERS DISEASE
- Tau Kinetics in Neurons and the Human Central Nervous System
- (2018) Chihiro Sato et al. NEURON
- Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms
- (2018) Hilary A. Weismiller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structures of filaments from Pick’s disease reveal a novel tau protein fold
- (2018) Benjamin Falcon et al. NATURE
- Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease
- (2018) Allison Kraus et al. ACTA NEUROPATHOLOGICA
- Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold
- (2018) Benjamin Falcon et al. ACTA NEUROPATHOLOGICA
- Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression
- (2018) Hsu-Hsin Chen et al. Scientific Reports
- Cryo-EM structures of tau filaments from Alzheimer’s disease
- (2017) Anthony W. P. Fitzpatrick et al. NATURE
- Ante-mortem detection of chronic wasting disease in recto-anal mucosa-associated lymphoid tissues from elk (Cervus elaphus nelsoni) using real-time quaking-induced conversion (RT-QuIC) assay: A blinded collaborative study
- (2017) Sireesha Manne et al. Prion
- Expression and purification of tau protein and its frontotemporal dementia variants using a cleavable histidine tag
- (2017) Thomas K. Karikari et al. PROTEIN EXPRESSION AND PURIFICATION
- RNA stores tau reversibly in complex coacervates
- (2017) Xuemei Zhang et al. PLOS BIOLOGY
- Differential Incorporation of Tau Isoforms in Alzheimer's Disease
- (2017) Marisol Espinoza et al. JOURNAL OF ALZHEIMERS DISEASE
- Integrated Organotypic Slice Cultures and RT-QuIC (OSCAR) Assay: Implications for Translational Discovery in Protein Misfolding Diseases
- (2017) Naveen Kondru et al. Scientific Reports
- Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice
- (2016) Jing L. Guo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Neuronal activity enhances tau propagation and tau pathology in vivo
- (2016) Jessica W Wu et al. NATURE NEUROSCIENCE
- Potential Pathways of Abnormal Tau and α-Synuclein Dissemination in Sporadic Alzheimer's and Parkinson's Diseases
- (2016) Heiko Braak et al. Cold Spring Harbor Perspectives in Biology
- Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC’s afferent and efferent connections
- (2015) Michiyo Iba et al. ACTA NEUROPATHOLOGICA
- A mechanistic model of tau amyloid aggregation based on direct observation of oligomers
- (2015) Sarah L. Shammas et al. Nature Communications
- Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms
- (2015) Maxime Derisbourg et al. Scientific Reports
- A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
- (2014) Zeshan Ahmed et al. ACTA NEUROPATHOLOGICA
- Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer’s disease or corticobasal degeneration brains
- (2014) Susana Boluda et al. ACTA NEUROPATHOLOGICA
- Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates
- (2014) Benjamin Falcon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
- (2014) David W. Sanders et al. NEURON
- Proteopathic tau seeding predicts tauopathy in vivo
- (2014) B. B. Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy
- (2013) M. Iba et al. JOURNAL OF NEUROSCIENCE
- Brain homogenates from human tauopathies induce tau inclusions in mouse brain
- (2013) Florence Clavaguera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural transitions in tau k18 on micelle binding suggest a hierarchy in the efficacy of individual microtubule-binding repeats in filament nucleation
- (2013) Patrick Barré et al. PROTEIN SCIENCE
- Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
- (2012) Alix de Calignon et al. NEURON
- Alzheimer's Disease: The Challenge of the Second Century
- (2011) D. M. Holtzman et al. Science Translational Medicine
- β-amyloid burden is not associated with rates of brain atrophy
- (2007) Keith A. Josephs et al. ANNALS OF NEUROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now