A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia

Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model

(2020) Chun Chen et al.   Science Advances

A phase II randomized trial of sodium oligomannate in Alzheimer’s dementia

(2020) Tao Wang et al.   Alzheimers Research & Therapy

Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease

(2019) Christopher H. van Dyck et al.   JAMA Neurology

Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression

(2019) Xinyi Wang et al.   CELL RESEARCH

Transfer of a healthy microbiota reduces amyloid and tau pathology in an Alzheimer’s disease animal model

(2019) Min-Soo Kim et al.   GUT

Gut microbiota: from the forgotten organ to a potential key player in the pathology of Alzheimer disease

(2019) Dong-oh Seo et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The gut microbiome in neurological disorders

(2019) John F Cryan et al.   LANCET NEUROLOGY

Placebo effects and racial and ethnic health disparities: an unjust and underexplored connection

(2018) Phoebe Friesen et al.   JOURNAL OF MEDICAL ETHICS

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Synthesis and bioassay of β-(1,4)-D-mannans as potential agents against Alzheimer's disease

(2013) Ru-wei Jiang et al.   ACTA PHARMACOLOGICA SINICA

Investigation of Influencing Factors on Higher Placebo Response in East Asian Versus Western Clinical Trials for Partial Epilepsy: A Meta-Analysis

(2013) Yosuke Tachibana et al.   CLINICAL DRUG INVESTIGATION

Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990–2010: a systematic review and analysis

(2013) Kit Yee Chan et al.   LANCET

Prevalence of dementia and major dementia subtypes in the Chinese populations: A meta-analysis of dementia prevalence surveys, 1980–2010

(2012) Yaodong Zhang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Reliability and validity of the Chinese version of the neuropsychiatric inventory in mainland China

(2011) Tao Wang et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Twelve-month metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment assessed using an empirically pre-defined statistical region-of-interest: Findings from the Alzheimer's Disease Neuroimaging Initiative

(2010) Kewei Chen et al.   NEUROIMAGE

Medial temporal lobe atrophy in vascular dementia: Visual temporal lobe rating scale

(2008) Hyun Cho et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS