In silico studies reveal structural deviations of mutant profilin-1 and interaction with riluzole and edaravone in amyotrophic lateral sclerosis

Characterizing molecular flexibility by combining lRMSD measures

(2019) F. Cazals et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The VASP-profilin1 (Pfn1) interaction is critical for efficient cell migration and is regulated by cell-substrate adhesion in a PKA-dependent manner

(2019) David Gau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In silico analysis of PFN1 related to amyotrophic lateral sclerosis

(2019) Gabriel Rodrigues Coutinho Pereira et al.   PLoS One

Incorporating upper motor neuron health in ALS drug discovery

(2018) Ina Dervishi et al.   DRUG DISCOVERY TODAY

ALS Genes in the Genomic Era and their Implications for FTD

(2018) Hung Phuoc Nguyen et al.   TRENDS IN GENETICS

Changes in biophysical characteristics of PFN1 due to mutation causing amyotrophic lateral sclerosis

(2018) Mina Nekouei et al.   METABOLIC BRAIN DISEASE

Role of Computational Methods in Going beyond X-ray Crystallography to Explore Protein Structure and Dynamics

(2018) Ashutosh Srivastava et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PubChem 2019 update: improved access to chemical data

(2018) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

Mutations at protein-protein interfaces: Small changes over big surfaces have large impacts on human health

(2017) Harry C. Jubb et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

ALS Clinical Trials Review: 20 Years of Failure. Are We Any Closer to Registering a New Treatment?

(2017) Dmitry Petrov et al.   Frontiers in Aging Neuroscience

Profilin1 biology and its mutation, actin(g) in disease

(2016) Duah Alkam et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

In silico methods for drug repurposing and pharmacology

(2016) Rachel A. Hodos et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

RRDistMaps: a UCSF Chimera tool for viewing and comparing protein distance maps

(2014) J. E. Chen et al.   BIOINFORMATICS

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

(2012) Chi-Hong Wu et al.   NATURE

FTMAP: extended protein mapping with user-selected probe molecules

(2012) C. H. Ngan et al.   NUCLEIC ACIDS RESEARCH

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details

(2009) V. Potapov et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Radius of gyration as an indicator of protein structure compactness

(2008) M. Yu. Lobanov et al.   MOLECULAR BIOLOGY