4.7 Article

The Impact of COVID-19-Related Lockdown on Diet and Serum Markers in Healthy Adults

Journal

NUTRIENTS
Volume 13, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/nu13041082

Keywords

lockdown; quarantine; nutrition; physical activity; serum biomarkers

Funding

  1. Slovenian Research Agency [P1-0386, I0-0035]

Ask authors/readers for more resources

This study aimed to investigate the impact of COVID-19-related lockdown on changes in dietary habits, physical activity, and serum markers in healthy adults. Results showed a decrease in diet quality and energy intake during lockdown, as well as lower physical activity levels. Despite no significant changes in body composition, there was a significant increase in serum glucose, total cholesterol, and LDL post-lockdown.
Due to limited data about the impact of lockdown on health status, the present study aimed to investigate the impact of COVID-19-related lockdown on changes in dietary habits, physical activity and serum markers in healthy adults. A total of 38 asymptomatic adults aged from 23 to 59 with a normal BMI (22.5 kg/m(2)) participated in baseline and post-lockdown measurements that included dietary and physical activity assessment, anthropometric measurements and blood samples; and the lockdown survey which included dietary assessment and questionnaires about changes in lifestyle and physical activity. A decreased diet quality during lockdown was observed (Healthy Eating Index reduced from 64.59 to 61.08), which returned to near baseline post-lockdown. Energy intake decreased during lockdown (p = 0.002) and returned to baseline post-lockdown. Despite lower physical activity levels during lockdown (p = 0.035), we observed no significant changes in body composition. However, we observed a significant increase in serum glucose (p = 0.005), total cholesterol (p = 0.003), and low-density lipoprotein (LDL) (p = 0.049) post-lockdown. Increase in serum glucose levels was pronounced in subjects with higher increase in energy intake (p = 0.039), increased omega-6 fatty acids intake (p = 0.016), those who were exposed to several risky contacts (p = 0.018, compared to those with less risky contacts) and those who were not active in nature (p = 0.008, compared to those active in nature). Increased serum LDL was correlated to decreased monounsaturated fatty acids intake (p = 0.028). Within the limits of this preliminary report, changes in serum markers observed among healthy subjects point to a possible impact of COVID-19-related lockdown on adults' health to be confirmed in larger groups.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Biochemistry & Molecular Biology

A Comparative Study of the Antioxidative Effects of Helichrysum italicum and Helichrysum arenarium Infusions

Katja Kramberger, Zala Jenko Praznikar, Alenka Baruca Arbeiter, Ana Petelin, Dunja Bandelj, Sasa Kenig

Summary: By comparing Helichrysum arenarium and Helichrysum italicum, it was found that different types of plants have varying antioxidative potential, influenced by the harvest date. Helichrysum italicum exhibited higher radical scavenging activity and could protect cells from oxidative stress.

ANTIOXIDANTS (2021)

Article Plant Sciences

Helichrysum italicum ssp. italicum Infusion Promotes Fat Oxidation in Hepatocytes and Stimulates Energy Expenditure and Fat Oxidation after Acute Ingestion in Humans: A Pilot Study

Sasa Kenig, Katja Kramberger, Ana Petelin, Dunja Bandelj, Alenka Baruca Arbeiter, Ana Miklavcic Visnjevec, Kelly Peeters, Nina Mohorko, Karin Sik Novak, Zala Jenko Praznikar

Summary: The study showed that ingestion of H. italicum infusion significantly increased resting energy expenditure and fat oxidation, and up-regulated lipid metabolism-related genes in hepatocytes, indicating its potential application in obesity prevention.

PLANTS-BASEL (2021)

Article Plant Sciences

Whole transcriptome expression array analysis of human colon fibroblasts culture treated with Helichrysum italicum supports its use in traditional medicine

Katja Kramberger, Darja Barlic-Maganja, Zala Jenko Praznikar, Tadeja Rezen, Damjana Rozman, Jure Praznikar, Sasa Kenig

Summary: The study aimed to explain the previously demonstrated effects of Helichrysum italicum (HI) and justify its use in traditional medicine. Transcriptome analysis revealed that HI infusion altered gene expression related to cytoskeletal rearrangement, cell growth, interleukin signaling, and transcriptional regulation. This indicates the main mode of HI action is wound healing through genes such as SERPING1, ARHGAP1, IL33 and CDKN1A.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

Article Food Science & Technology

Helichrysum italicum (Roth) G. Don and Helichrysum arenarium (L.) Moench Infusion Consumption Affects the Inflammatory Status and the Composition of Human Gut Microbiota in Patients with Traits of Metabolic Syndrome: A Randomized Comparative Study

Ana Petelin, Karin Sik Novak, Matjaz Hladnik, Dunja Bandelj, Alenka Baruca Arbeiter, Katja Kramberger, Sasa Kenig, Zala Jenko Praznikar

Summary: The consumption of Helichrysum italicum and Helichrysum arenarium infusions can improve gut microbiota, reduce inflammation, and enhance gut barrier function, making them potential prebiotics for improving obesity and metabolic syndrome.

FOODS (2022)

Article Biochemistry & Molecular Biology

Impact of Sample Preparation Methods on Single-Cell X-ray Microscopy and Light Elemental Analysis Evaluated by Combined Low Energy X-ray Fluorescence, STXM and AFM

Lucia Merolle, Lorella Pascolo, Luisa Zupin, Pietro Parisse, Valentina Bonanni, Gianluca Gariani, Sasa Kenig, Diana E. Bedolla, Sergio Crovella, Giuseppe Ricci, Stefano Iotti, Emil Malucelli, George Kourousias, Alessandra Gianoncelli

Summary: Although X-ray fluorescence microscopy is widely used for single-cell analysis, sample preparation remains a major challenge. The information on sample treatment is inadequate and unclear, leading to wasted time and jeopardizing the success of the experiment. Various fixation methods have been described, but none have been systematically tested for synchrotron X-ray microscopy.

MOLECULES (2023)

Article Nutrition & Dietetics

Could Gut Microbiota Composition Be a Useful Indicator of a Long-Term Dietary Pattern?

Karin Sik Novak, Nives Bogataj Jontez, Ana Petelin, Matjaz Hladnik, Alenka Baruca Arbeiter, Dunja Bandelj, Jure Praznikar, Sasa Kenig, Nina Mohorko, Zala Jenko Praznikar

Summary: This study aimed to determine whether gut microbiota composition could be a useful indicator of a long-term dietary pattern. The results suggest that gut microbiota composition at the genus level is not a reliable predictor of an individual's dietary pattern, except for vegans who have a high abundance of Prevotella 9. A combination of multiple variables, including anthropometric measurements, serum biomarkers, lifestyle factors, gastrointestinal symptoms, psychological factors, and specific nutrient intake, is more important in predicting an individual's microbiota composition cluster with 91% accuracy than dietary intake alone.

NUTRIENTS (2023)

Article Nutrition & Dietetics

Habitual low carbohydrate high fat diet compared with omnivorous, vegan, and vegetarian diets

Nives Bogataj Jontez, Sasa Kenig, Karin Sik Novak, Ana Petelin, Zala Jenko Praznikar, Nina Mohorko

Summary: This study compared the dietary patterns of individuals following LCHF, vegan, vegetarian, and omnivorous diets. The results showed that compared to other groups, the LCHF group had higher intakes of saturated fats, cholesterol, and animal proteins, while the intakes of sugars and dietary fibers were lower. The levels of total and LDL cholesterol were significantly higher in the LCHF group. Thus, it is recommended to select healthy fat sources, increase dietary fiber intake, and partially replace animal sources with plant sources in the LCHF diet.

FRONTIERS IN NUTRITION (2023)

Article Rehabilitation

LOW ENERGY AVAILABILITY AND CARBOHYDRATE INTAKE IN COMPETITIVE ADOLESCENT CLIMBERS

Vesna Simic, Spela Jevsnik, Nina Mohorko

Summary: Competitive adolescent sport climbers often adopt very low energy intake for better strength-to-mass ratio, but this can negatively impact their health and performance. A study on Slovenian Youth Climbing Team members aged 13-18 found that most participants did not meet the recommended energy and nutrient intake, with insufficient carbohydrates, calcium, and vitamin D. Iron intake was also inadequate, particularly in female climbers, and menstrual dysfunction was observed in some female participants. The study suggests the need for nutritional education and regular assessment for adolescent sport climbers.

KINESIOLOGY (2022)

Article Biochemistry & Molecular Biology

Helichrysum italicum (Roth) G. Don and Helichrysum arenarium (L.) Moench infusions in reversing the traits of metabolic syndrome: a double-blind randomized comparative trial

Sasa Kenig, Katja Kramberger, Karin Sik Novak, Igor Karnjus, Dunja Bandelj, Ana Petelin, Zala Jenko Praznikar

Summary: A study found that consuming infusions of Helichrysum italicum subsp. italicum or Helichrysum arenarium can be beneficial for improving metabolic syndrome. Helichrysum italicum subsp. italicum reduces body weight, body mass index, and body fat, while Helichrysum arenarium lowers blood glucose levels and improves lipid profiles. Both infusions decrease LDL and improve serum antioxidant properties.

FOOD & FUNCTION (2022)

Article Behavioral Sciences

The effect of COVID-19 lockdown on mental health, gut microbiota composition and serum cortisol levels

Karin Sik Novak, Nives Bogataj Jontez, Sasa Kenig, Matjaz Hladnik, Alenka Baruca Arbeiter, Dunja Bandelj, Masa Cernelic Bizjak, Ana Petelin, Nina Mohorko, Zala Jenko Praznikar

Summary: This study aimed to assess the impact of COVID-19 lockdown on mental health, gut microbiota composition, and stress marker serum cortisol in asymptomatic individuals. The results showed that during the lockdown, individuals reported higher body dissatisfaction, anxiety, and lower positive affect. Females had significantly increased serum cortisol levels post-lockdown, which correlated with perceived stress and anxiety. Changes in gut microbiota composition were also observed during the lockdown.

STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS (2022)

No Data Available