MYRF: A Mysterious Membrane-Bound Transcription Factor Involved in Myelin Development and Human Diseases

The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification

(2020) Sally H. Cross et al.   PLoS Genetics

Genetic Evidence that Dorsal Spinal Oligodendrocyte Progenitor Cells are Capable of Myelinating Ventral Axons Effectively in Mice

(2020) Minxi Fang et al.   Neuroscience Bulletin

MYRF haploinsufficiency causes 46,XY and 46,XX disorders of sex development: bioinformatics consideration

(2019) Kohei Hamanaka et al.   HUMAN MOLECULAR GENETICS

Cyclin-dependent Kinase 18 Promotes Oligodendrocyte Precursor Cell Differentiation through Activating the Extracellular Signal-Regulated Kinase Signaling Pathway

(2019) Yuchen Pan et al.   Neuroscience Bulletin

Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice

(2019) Sarah J. Garnai et al.   PLoS Genetics

Novel truncation mutations in MYRF cause autosomal dominant high hyperopia mapped to 11p12–q13.3

(2019) Xueshan Xiao et al.   HUMAN GENETICS

Myrf guides target gene selection of transcription factor Sox10 during oligodendroglial development

(2019) Jessica Aprato et al.   NUCLEIC ACIDS RESEARCH

MYRF is associated with encephalopathy with reversible myelin vacuolization

(2018) Hirokazu Kurahashi et al.   ANNALS OF NEUROLOGY

Interactive repression of MYRF self-cleavage and activity in oligodendrocyte differentiation by TMEM98 protein

(2018) Hao Huang et al.   JOURNAL OF NEUROSCIENCE

Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands

(2017) Sheng Chih Jin et al.   NATURE GENETICS

Does the Association BetweenTMEM98and Nanophthalmos Require Further Confirmation?

(2015) Wenmin Sun et al.   JAMA Ophthalmology

Mutation inTMEM98in a Large White Kindred With Autosomal Dominant Nanophthalmos Linked to 17p12-q12

(2014) Mona S. Awadalla et al.   JAMA Ophthalmology

A Bacteriophage Tailspike Domain Promotes Self-Cleavage of a Human Membrane-Bound Transcription Factor, the Myelin Regulatory Factor MYRF

(2013) Zhihua Li et al.   PLOS BIOLOGY

MYRF Is a Membrane-Associated Transcription Factor That Autoproteolytically Cleaves to Directly Activate Myelin Genes

(2013) Helena Bujalka et al.   PLOS BIOLOGY

The Transcription Factors Sox10 and Myrf Define an Essential Regulatory Network Module in Differentiating Oligodendrocytes

(2013) Julia Hornig et al.   PLoS Genetics

Myelin Gene Regulatory Factor Is Required for Maintenance of Myelin and Mature Oligodendrocyte Identity in the Adult CNS

(2012) M. Koenning et al.   JOURNAL OF NEUROSCIENCE

Myelin Gene Regulatory Factor Is a Critical Transcriptional Regulator Required for CNS Myelination

(2009) Ben Emery et al.   CELL

06-P022 Rwhs is a mouse model for Bochdalek congenital diaphragmatic hernia in humans

(2009) Sally Cross et al.   MECHANISMS OF DEVELOPMENT