Journal
MATERIALS
Volume 14, Issue 8, Pages -Publisher
MDPI
DOI: 10.3390/ma14081960
Keywords
scaffold; bone tissue engineering; starch; dielectric properties; hydroxyapatite; free space measurement
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Funding
- Research Management Centre, Universiti Putra Malaysia
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Hydroxyapatite (HA) is widely used in tissue engineering due to its high mechanical stress and biocompatibility. However, its brittleness limits applications. Combining HA with starch and other biomaterials can enhance scaffold properties and improve performance.
Hydroxyapatite (HA) has been widely used as a scaffold in tissue engineering. HA possesses high mechanical stress and exhibits particularly excellent biocompatibility owing to its similarity to natural bone. Nonetheless, this ceramic scaffold has limited applications due to its apparent brittleness. Therefore, this had presented some difficulties when shaping implants out of HA and for sustaining a high mechanical load. Fortunately, these drawbacks can be improved by combining HA with other biomaterials. Starch was heavily considered for biomedical device applications in favor of its low cost, wide availability, and biocompatibility properties that complement HA. This review provides an insight into starch/HA composites used in the fabrication of bone tissue scaffolds and numerous factors that influence the scaffold properties. Moreover, an alternative characterization of scaffolds via dielectric and free space measurement as a potential contactless and nondestructive measurement method is also highlighted.
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