Ureate Titanium Catalysts for Hydroaminoalkylation: Using Ligand Design to Increase Reactivity and Utility

Fast Titanium-Catalyzed Hydroaminomethylation of Alkenes and the Formal Conversion of Methylamine

(2020) Jens Bielefeld et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Cross-Linking of Catalytically Synthesized Poly(Aminonorbornenes)

(2020) Nirmalendu Kuanr et al.   MACROMOLECULES

Linear Hydroaminoalkylation Products from Alkyl‐Substituted Alkenes

(2020) Michael Warsitz et al.   CHEMISTRY-A EUROPEAN JOURNAL

Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders

(2020) Satoru Noji et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Cyclic Ureate Tantalum Catalyst for Preferential Hydroaminoalkylation with Aliphatic Amines. Mechanistic Insights into Substrate Controlled Reactivity

(2020) Pargol Daneshmand et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploiting Natural Complexity: Synthetic Terpenoid‐Alkaloids by Regioselective and Diastereoselective Hydroaminoalkylation Catalysis

(2019) Rebecca C. DiPucchio et al.   ChemCatChem

Planar‐chiral [2.2]Paracyclophane‐based Pyridonates as Ligands for Tantalum‐catalyzed Hydroaminoalkylation

(2019) Carolin Braun et al.   ChemCatChem

New Titanium Complexes and Their Use in Hydroamination and Hydroaminoalkylation Reactions

(2019) Jens Bielefeld et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Titanium‐Catalyzed Hydroaminoalkylation of Ethylene

(2019) Michael Rosien et al.   CHEMISTRY-A EUROPEAN JOURNAL

Trimethylsilyl-Protected Alkynes as Selective Cross-Coupling Partners in Titanium-Catalyzed [2+2+1] Pyrrole Synthesis

(2018) Hsin-Chun Chiu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic and Atom-Economic Csp3 −Csp3 Bond Formation: Alkyl Tantalum Ureates for Hydroaminoalkylation

(2018) Rebecca C. DiPucchio et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ti-Catalyzed Hydroamination for the Synthesis of Amine-Containing π-Conjugated Materials

(2018) Han Hao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Regio- and Stereoselective Hydroamination of Alkynes Using an Ammonia Surrogate: Synthesis of N-Silylenamines as Reactive Synthons

(2018) Erica K. J. Lui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Titanium Catalysts with Linked Indenyl–Amido Ligands for Hydroamination and Hydroaminoalkylation Reactions

(2018) Stefan H. Rohjans et al.   ORGANOMETALLICS

Discovery of an MLLT1/3 YEATS Domain Chemical Probe

(2018) Moses Moustakim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Silylenamines as Reactive Intermediates: Hydroamination for the Modular Synthesis of Selectively Substituted Pyridines

(2018) Erica K. J. Lui et al.   ORGANIC LETTERS

Dative Directing Group Effects in Ti-Catalyzed [2+2+1] Pyrrole Synthesis: Chemo- and Regioselective Alkyne Heterocoupling

(2018) Hsin-Chun Chiu et al.   ACS Catalysis

Bis(tert-butylimido)bis(N,O-chelate)tungsten(VI) Complexes: Probing Amidate and Pyridonate Hemilability

(2017) Joseph M. Clarkson et al.   INORGANIC CHEMISTRY

In Situ Generation of a Regio- and Diastereoselective Hydroaminoalkylation Catalyst Using Commercially Available Starting Materials

(2017) Peter M. Edwards et al.   ORGANIC LETTERS

Mechanistic Insights into Scandium-Catalyzed Hydroaminoalkylation of Olefins with Amines: Origin of Regioselectivity and Charge-Based Prediction Model

(2017) Fan Liu et al.   ORGANOMETALLICS

Ligand Effects and Kinetic Investigations of Sterically Accessible 2-Pyridonate Tantalum Complexes for Hydroaminoalkylation

(2017) Jason W. Brandt et al.   ACS Catalysis

Facile Synthesis and Isolation of Secondary Amines via a Sequential Titanium(IV)-Catalyzed Hydroamination and Palladium-Catalyzed Hydrogenation

(2016) Erica K. J. Lui et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthetic Reactions Using Low-valent Titanium Reagents Derived from Ti(OR)4or CpTiX3(X = O-i-Pr or Cl) in the Presence of Me3SiCl and Mg

(2016) Sentaro Okamoto   CHEMICAL RECORD

One-Pot Procedure for the Synthesis of 1,5-Benzodiazepines fromN-Allyl-2-bromoanilines

(2016) Marco Weers et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Synthesis of Secondary Amine-Containing Polymers: Variable Hydrogen Bonding for Tunable Rheological Properties

(2016) Mitchell R. Perry et al.   MACROMOLECULES

An Aminopyridinato Titanium Catalyst for the Intramolecular Hydroaminoalkylation of Secondary Aminoalkenes

(2015) Jaika Dörfler et al.   ADVANCED SYNTHESIS & CATALYSIS

Efficient Access to Titanaaziridines by CH Activation ofN-Methylanilines at Ambient Temperature

(2015) Manfred Manßen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intermolecular hydroaminoalkylation of alkenes and dienes using a titanium mono(formamidinate) catalyst

(2015) Jaika Dörfler et al.   DALTON TRANSACTIONS

Catalytic formal [2+2+1] synthesis of pyrroles from alkynes and diazenes via TiII/TiIV redox catalysis

(2015) Zachary W. Gilbert et al.   Nature Chemistry

A 2,6-Bis(phenylamino)pyridinato Titanium Catalyst for the Highly Regioselective Hydroaminoalkylation of Styrenes and 1,3-Butadienes

(2014) Jaika Dörfler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Commercially Available Tantalum Catalyst for the Highly Regioselective Intermolecular Hydroaminoalkylation of Styrenes

(2014) Jaika Dörfler et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

2-Pyridonate Tantalum Complexes for the Intermolecular Hydroaminoalkylation of Sterically Demanding Alkenes

(2014) Eugene Chong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphoramidate Tantalum Complexes for Room-Temperature CH Functionalization: Hydroaminoalkylation Catalysis

(2013) Pierre Garcia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Titanium-Catalyzed Intermolecular Hydroaminoalkylation of Conjugated Dienes

(2013) Till Preuß et al.   CHEMISTRY-A EUROPEAN JOURNAL

TaMe3Cl2-Catalyzed Intermolecular Hydroaminoalkylation: A Simple Complex for Enhanced Reactivity and Expanded Substrate Scope

(2013) Zhengxing Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tantalum Catalyzed Hydroaminoalkylation for the Synthesis of α- and β-Substituted N-Heterocycles

(2013) Philippa R. Payne et al.   ORGANIC LETTERS

2-Pyridonate Titanium Complexes for Chemoselectivity. Accessing Intramolecular Hydroaminoalkylation over Hydroamination

(2013) Eugene Chong et al.   ORGANIC LETTERS

Synthesis and Structure of Group 4 Symmetric Amidinate Complexes and Their Reactivity in the Polymerization of α-Olefins

(2013) Tatyana Elkin et al.   ORGANOMETALLICS

Aminopyridinato Titanium Catalysts for the Hydroaminoalkylation of Alkenes and Styrenes

(2012) Jaika Dörfler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Applied Hydroformylation

(2012) Robert Franke et al.   CHEMICAL REVIEWS

The Mechanism of the Titanium-Catalyzed Hydroaminoalkylation of Alkenes

(2011) Insa Prochnow et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric hydroamination catalyzed by in situ generated chiral amidate and ureate complexes of zirconium — Probing the role of the tether in ligand design

(2011) Philippa R. Payne et al.   CANADIAN JOURNAL OF CHEMISTRY

The Methylation Effect in Medicinal Chemistry

(2011) Eliezer J. Barreiro et al.   CHEMICAL REVIEWS

Mechanistic Elucidation of Intramolecular Aminoalkene Hydroamination Catalyzed by a Tethered Bis(ureate) Complex: Evidence for Proton-Assisted C–N Bond Formation at Zirconium

(2011) David C. Leitch et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

[Ind2TiMe2]: A Catalyst for the Hydroaminomethylation of Alkenes and Styrenes

(2010) Raphael Kubiak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Applications oftert-Butanesulfinamide

(2010) MaryAnn T. Robak et al.   CHEMICAL REVIEWS

Titanium-Catalyzed Hydroaminoalkylation of Alkenes by CH Bond Activation at sp3Centers in the α-Position to a Nitrogen Atom

(2009) Raphael Kubiak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Hydroaminoalkylation

(2009) Peter W. Roesky   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrabenzyltitanium: An Improved Catalyst for the Activation of sp3CH Bonds Adjacent to Nitrogen Atoms

(2009) Insa Prochnow et al.   ChemCatChem

Zirconium bis(pyridonate): a modified amidate complex for enhanced substrate scope in aminoalkene cyclohydroamination

(2009) Jason A. Bexrud et al.   DALTON TRANSACTIONS

Broadening the Scope of Group 4 Hydroamination Catalysis Using a Tethered Ureate Ligand

(2009) David C. Leitch et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydroamination: Direct Addition of Amines to Alkenes and Alkynes

(2008) Thomas E. Müller et al.   CHEMICAL REVIEWS