An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness
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Title
An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness
Authors
Keywords
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Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-05-11
DOI
10.1038/s41467-021-22971-x
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Note: Only part of the references are listed.- Phosphorylation-dependent regulation of the NOTCH1 intracellular domain by dual-specificity tyrosine-regulated kinase 2
- (2019) Rosario Morrugares et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Next-Generation Sequencing Approach to Non–Small Cell Lung Carcinoma Yields More Actionable Alterations
- (2018) Mitra Mehrad et al. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Numb has distinct function in lung adenocarcinoma and squamous cell carcinoma
- (2018) Hajime Kikuchi et al. Oncotarget
- MYEOV functions as an amplified competing endogenous RNA in promoting metastasis by activating TGF-β pathway in NSCLC
- (2018) Lishan Fang et al. ONCOGENE
- Response rates to single-agent chemotherapy after exposure to immune checkpoint inhibitors in advanced non-small cell lung cancer
- (2017) Gustavo Schvartsman et al. LUNG CANCER
- Gamma Secretase Inhibition by BMS-906024 Enhances Efficacy of Paclitaxel in Lung Adenocarcinoma
- (2017) Katherine M. Morgan et al. MOLECULAR CANCER THERAPEUTICS
- Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC
- (2017) Junchao Cai et al. Nature Communications
- Targeting Notch degradation system provides promise for breast cancer therapeutics
- (2016) Jing Liu et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Fbxw7 Tumor Suppressor
- (2016) Jun Cao et al. MEDICINE
- Phosphorylation-dependent regulation of Notch1 signaling: the fulcrum of Notch1 signaling
- (2015) Hye-Jin Lee et al. BMB Reports
- Targeting Notch, Hedgehog and Wnt pathways in cancer stem cells: clinical update
- (2015) Naoko Takebe et al. Nature Reviews Clinical Oncology
- Metastatic sites and survival in lung cancer
- (2014) M. Riihimäki et al. LUNG CANCER
- Comprehensive molecular profiling of lung adenocarcinoma
- (2014) Eric A. Collisson et al. NATURE
- Cyclin C is a haploinsufficient tumour suppressor
- (2014) Na Li et al. NATURE CELL BIOLOGY
- Therapeutic modulation of Notch signalling — are we there yet?
- (2014) Emma R. Andersson et al. NATURE REVIEWS DRUG DISCOVERY
- Tumor Cell Dissemination: Emerging Biological Insights from Animal Models and Cancer Patients
- (2013) Yibin Kang et al. CANCER CELL
- Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53
- (2013) S. Licciulli et al. CANCER RESEARCH
- Notch Pathway Activity Identifies Cells with Cancer Stem Cell-like Properties and Correlates with Worse Survival in Lung Adenocarcinoma
- (2013) K. A. Hassan et al. CLINICAL CANCER RESEARCH
- NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
- (2013) H. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch in the Intestine: Regulation of Homeostasis and Pathogenesis
- (2012) Taeko K. Noah et al. Annual Review of Physiology
- Molecular Pathways: Context-Dependent Approaches to Notch Targeting as Cancer Therapy
- (2012) A. M. Egloff et al. CLINICAL CANCER RESEARCH
- Comparative Genomic Analysis of Esophageal Adenocarcinoma and Squamous Cell Carcinoma
- (2012) Nishant Agrawal et al. Cancer Discovery
- Notch signalling in cancer progression and bone metastasis
- (2011) N Sethi et al. BRITISH JOURNAL OF CANCER
- Activated Notch1 Induces Lung Adenomas in Mice and Cooperates with Myc in the Generation of Lung Adenocarcinoma
- (2011) T. D. Allen et al. CANCER RESEARCH
- Tumor Metastasis: Molecular Insights and Evolving Paradigms
- (2011) Scott Valastyan et al. CELL
- Selective repression of Notch pathway target gene transcription
- (2011) John W. Cave DEVELOPMENTAL BIOLOGY
- Interactions between cancer stem cells and their niche govern metastatic colonization
- (2011) Ilaria Malanchi et al. NATURE
- Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma
- (2011) N. J. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Mutational Landscape of Head and Neck Squamous Cell Carcinoma
- (2011) N. Stransky et al. SCIENCE
- Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy
- (2010) James P. Sullivan et al. CANCER AND METASTASIS REVIEWS
- Novel Integrative Methods for Gene Discovery Associated With Head and Neck Squamous Cell Carcinoma Development
- (2009) Ian M. Smith et al. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
- Identification of novel candidate target genes, including EPHB3, MASP1 and SSTat 3q26.2–q29 in squamous cell carcinoma of the lung
- (2009) Ji Un Kang et al. BMC CANCER
- The Notch signaling pathway: Transcriptional regulation at Notch target genes
- (2009) T. Borggrefe et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Alterations of the Notch pathway in lung cancer
- (2009) Britta Westhoff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch Signaling in Leukemia
- (2008) Jon C. Aster et al. Annual Review of Pathology-Mechanisms of Disease
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
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