The Bluetongue Disabled Infectious Single Animal (DISA) Vaccine Platform Based on Deletion NS3/NS3a Protein Is Safe and Protective in Cattle and Enables DIVA

Within-farm transmission characteristics of bluetongue virus serotype 8 in cattle and sheep in the Netherlands, 2007-2008

(2021) Thomas J. Hagenaars et al.   PLoS One

Putative Novel Serotypes ‘33’ and ‘35’ in Clinically Healthy Small Ruminants in Mongolia Expand the Group of Atypical BTV

(2020) Christina Ries et al.   Viruses-Basel

Novel Function of Bluetongue Virus NS3 Protein in Regulation of the MAPK/ERK Signaling Pathway

(2019) Cindy Kundlacz et al.   JOURNAL OF VIROLOGY

Characterization of bluetongue virus serotype 28

(2019) Velizar Bumbarov et al.   Transboundary and Emerging Diseases

Virus‐induced autophagic degradation of STAT 2 as a mechanism for interferon signaling blockade

(2019) Miguel Avia et al.   EMBO REPORTS

Vector competence is strongly affected by a small deletion or point mutations in bluetongue virus

(2019) René G. P. van Gennip et al.   Parasites & Vectors

Prospects of Next-Generation Vaccines for Bluetongue

(2019) Piet A. van Rijn   Frontiers in Veterinary Science

One after the other: A novel Bluetongue virus strain related to Toggenburg virus detected in the Piedmont region (North-western Italy), extends the panel of novel atypical BTV strains

(2018) Maurilia Marcacci et al.   Transboundary and Emerging Diseases

Diagnostic DIVA tests accompanying the Disabled Infectious Single Animal (DISA) vaccine platform for African horse sickness

(2018) Piet A. van Rijn et al.   VACCINE

African horse sickness virus (AHSV) with a deletion of 77 amino acids in NS3/NS3a protein is not virulent and a safe promising AHS Disabled Infectious Single Animal (DISA) vaccine platform

(2018) Piet A. van Rijn et al.   VACCINE

Novel putative Bluetongue virus in healthy goats from Sardinia, Italy

(2017) Giovanni Savini et al.   INFECTION GENETICS AND EVOLUTION

Bluetongue virus serotype 27: Experimental infection of goats, sheep and cattle with three BTV-27 variants reveal atypical characteristics and likely direct contact transmission BTV-27 between goats

(2017) E. Bréard et al.   Transboundary and Emerging Diseases

Bluetongue Disabled Infectious Single Animal (DISA) vaccine: Studies on the optimal route and dose in sheep

(2017) Piet A. van Rijn et al.   VACCINE

Current and next-generation bluetongue vaccines: Requirements, strategies, and prospects for different field situations

(2016) Femke Feenstra et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines

(2016) Cristina C. Celma et al.   JOURNAL OF VIROLOGY

Emergence of a Novel Bluetongue Virus Serotype, China 2014

(2016) E. C. Sun et al.   Transboundary and Emerging Diseases

Requirements and comparative analysis of reverse genetics for bluetongue virus (BTV) and African horse sickness virus (AHSV)

(2016) Piet A. van Rijn et al.   Virology Journal

Characterization of a second open reading frame in genome segment 10 of bluetongue virus

(2015) Meredith Stewart et al.   JOURNAL OF GENERAL VIROLOGY

Non-structural protein NS3/NS3a is required for propagation of bluetongue virus in Culicoides sonorensis

(2015) Femke Feenstra et al.   Parasites & Vectors

Development of a competitive ELISA for NS3 antibodies as DIVA test accompanying the novel Disabled Infectious Single Animal (DISA) vaccine for Bluetongue

(2015) Mirriam G.J. Tacken et al.   VACCINE

Application of Bluetongue Disabled Infectious Single Animal (DISA) vaccine for different serotypes by VP2 exchange or incorporation of chimeric VP2

(2015) Femke Feenstra et al.   VACCINE

Bluetongue virus without NS3/NS3a expression is not virulent and protects against virulent bluetongue virus challenge

(2014) F. Feenstra et al.   JOURNAL OF GENERAL VIROLOGY

A Synthetic Biology Approach for a Vaccine Platform against Known and Newly Emerging Serotypes of Bluetongue Virus

(2014) S. F. Nunes et al.   JOURNAL OF VIROLOGY

Bluetongue Virus Nonstructural Protein NS3/NS3a Is Not Essential for Virus Replication

(2014) René G. P. van Gennip et al.   PLoS One

Cost assessment of the movement restriction policy in France during the 2006 bluetongue virus episode (BTV-8)

(2014) Damian Tago et al.   PREVENTIVE VETERINARY MEDICINE

VP2-serotyped live-attenuated bluetongue virus without NS3/NS3a expression provides serotype-specific protection and enables DIVA

(2014) Femke Feenstra et al.   VACCINE

Rapid Generation of Replication-Deficient Monovalent and Multivalent Vaccines for Bluetongue Virus: Protection against Virulent Virus Challenge in Cattle and Sheep

(2013) C. C. P. Celma et al.   JOURNAL OF VIROLOGY

Bluetongue Virus RNA Detection by Real-Time RT-PCR in Post-Vaccination Samples from Cattle

(2013) I. De Leeuw et al.   Transboundary and Emerging Diseases

Bluetongue virus with mutated genome segment 10 to differentiate infected from vaccinated animals: A genetic DIVA approach

(2013) P.A. van Rijn et al.   VACCINE

Induction and control of the type I interferon pathway by Bluetongue virus

(2013) Damien Vitour et al.   VIRUS RESEARCH

Sustained high-throughput polymerase chain reaction diagnostics during the European epidemic of Bluetongue virus serotype 8

(2012) Piet A. van Rijn et al.   JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION

Rescue of Recent Virulent and Avirulent Field Strains of Bluetongue Virus by Reverse Genetics

(2012) René G. P. van Gennip et al.   PLoS One

Bluetongue Viruses Based on Modified-Live Vaccine Serotype 6 with Exchanged Outer Shell Proteins Confer Full Protection in Sheep against Virulent BTV8

(2012) René G. P. van Gennip et al.   PLoS One

Bluetongue virus serotype 6 in Europe in 2008—Emergence and disappearance of an unexpected non-virulent BTV

(2012) Piet A. van Rijn et al.   VETERINARY MICROBIOLOGY

Bluetongue virus serotype 26: Infection kinetics, pathogenesis and possible contact transmission in goats

(2012) C.A. Batten et al.   VETERINARY MICROBIOLOGY

Detection of a Fourth Orbivirus Non-Structural Protein

(2011) Mourad Belhouchet et al.   PLoS One

Bluetongue: History, global epidemiology, and pathogenesis

(2011) N. James Maclachlan   PREVENTIVE VETERINARY MEDICINE

Identification and Characterization of a Novel Non-Structural Protein of Bluetongue Virus

(2011) Maxime Ratinier et al.   PLoS Pathogens

Full Genome Characterisation of Bluetongue Virus Serotype 6 from the Netherlands 2008 and Comparison to Other Field and Vaccine Strains

(2010) Sushila Maan et al.   PLoS One

Occurrence and spatial distribution of Toggenburg Orbivirus in Switzerland

(2010) Valérie Chaignat et al.   SMALL RUMINANT RESEARCH

Bluetongue virus RNA detection by RT-qPCR in blood samples of sheep vaccinated with a commercially available inactivated BTV-8 vaccine

(2010) Adolf Steinrigl et al.   VACCINE

The Pathology and Pathogenesis of Bluetongue

(2009) N.J. Maclachlan et al.   JOURNAL OF COMPARATIVE PATHOLOGY

A Viral Nonstructural Protein Regulates Bluetongue Virus Trafficking and Release

(2009) C. C. P. Celma et al.   JOURNAL OF VIROLOGY

Financial consequences of the Dutch bluetongue serotype 8 epidemics of 2006 and 2007

(2009) A.G.J. Velthuis et al.   PREVENTIVE VETERINARY MEDICINE

A DIVA system based on the detection of antibodies to non-structural protein 3 (NS3) of bluetongue virus

(2009) Sílvia C. Barros et al.   VETERINARY MICROBIOLOGY

Experimental Reproduction of Severe Bluetongue in Sheep

(2008) N. J. Maclachlan et al.   VETERINARY PATHOLOGY