A 4-gene-based hypoxia signature is associated with tumor immune microenvironment and predicts the prognosis of pancreatic cancer patients

B cells are associated with survival and immunotherapy response in sarcoma

(2020) Florent Petitprez et al.   NATURE

B cells and tertiary lymphoid structures promote immunotherapy response

(2020) Beth A. Helmink et al.   NATURE

Author Correction: Tertiary lymphoid structures improve immunotherapy and survival in melanoma

(2020) Rita Cabrita et al.   NATURE

Identification of a Hypoxia-Associated Signature for Lung Adenocarcinoma

(2020) Zhuomao Mo et al.   Frontiers in Genetics

A hypoxia-related signature for clinically predicting diagnosis, prognosis and immune microenvironment of hepatocellular carcinoma patients

(2020) Baohui Zhang et al.   Journal of Translational Medicine

Tumour-associated macrophages-derived CXCL8 determines immune evasion through autonomous PD-L1 expression in gastric cancer

(2019) Chao Lin et al.   GUT

Biomarkers for Predicting Response to Immunotherapy with Immune Checkpoint Inhibitors in Cancer Patients

(2019) Michael J. Duffy et al.   CLINICAL CHEMISTRY

Tetrandrine suppresses lung cancer growth and induces apoptosis, potentially via the VEGF/HIF-1α/ICAM-1 signaling pathway

(2018) Zhuo Chen et al.   Oncology Letters

Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors

(2018) Diego Sanchez-Martinez et al.   Theranostics

The hypoxic tumour microenvironment

(2018) Varvara Petrova et al.   Oncogenesis

Pancreatic Ductal Adenocarcinoma: A Strong Imbalance of Good and Bad Immunological Cops in the Tumor Microenvironment

(2018) Etienne D. Foucher et al.   Frontiers in Immunology

Emerging Therapies and Future Directions in Targeting the Tumor Stroma and Immune System in the Treatment of Pancreatic Adenocarcinoma

(2018) Daniel Ahn et al.   Cancers

TIP: A web server for resolving tumor immunophenotype profiling

(2018) Liwen Xu et al.   CANCER RESEARCH

Tumor microenvironment participates in metastasis of pancreatic cancer

(2018) Bo Ren et al.   Molecular Cancer

Reversal of tumor acidosis by systemic buffering reactivates NK cells to express IFN-γ and induces NK cell-dependent lymphoma control without other immunotherapies

(2017) Johann Pötzl et al.   INTERNATIONAL JOURNAL OF CANCER

HIF1/2α mediates hypoxia-induced LDHA expression in human pancreatic cancer cells

(2017) Xin-gang Cui et al.   Oncotarget

Sensitization of glioblastoma tumor micro-environment to chemo- and immunotherapy by Galectin-1 intranasal knock-down strategy

(2017) Matthias Van Woensel et al.   Scientific Reports

Genetics and biology of pancreatic ductal adenocarcinoma

(2016) Haoqiang Ying et al.   GENES & DEVELOPMENT

The impact of hypoxia on tumor-associated macrophages

(2016) Anne-Theres Henze et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia-induced oxidative stress promotes MUC4 degradation via autophagy to enhance pancreatic cancer cells survival

(2016) S Joshi et al.   ONCOGENE

Hypoxic stress: obstacles and opportunities for innovative immunotherapy of cancer

(2016) S Chouaib et al.   ONCOGENE

Advances in the targeting of HIF-1α and future therapeutic strategies for glioblastoma multiforme

(2016) Gang Wang et al.   ONCOLOGY REPORTS

Lactate Contribution to the Tumor Microenvironment: Mechanisms, Effects on Immune Cells and Therapeutic Relevance

(2016) Susana Romero-Garcia et al.   Frontiers in Immunology

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia

(2015) K. E. Lee et al.   Cancer Discovery

Co-expression of CXCL8 and HIF-1α is associated with metastasis and poor prognosis in hepatocellular carcinoma

(2015) Xian-Peng Li et al.   Oncotarget

The role of hypoxia in pancreatic cancer: a potential therapeutic target?

(2015) Mert Erkan et al.   Expert Review of Gastroenterology & Hepatology

Pancreatic cancer: Update on immunotherapies and algenpantucel-L

(2015) Kinsey A. McCormick et al.   Human Vaccines & Immunotherapeutics

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

Pancreatic Ductal Adenocarcinoma Contains an Effector and Regulatory Immune Cell Infiltrate that Is Altered by Multimodal Neoadjuvant Treatment

(2014) Kendall C. Shibuya et al.   PLoS One

Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner

(2013) T. A. Mace et al.   CANCER RESEARCH

Intercellular adhesion molecule-1 (ICAM-1) expression correlates with oral cancer progression and induces macrophage/cancer cell adhesion

(2013) Yu Usami et al.   INTERNATIONAL JOURNAL OF CANCER

Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancer

(2013) SUFIAN S. AHMAD et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes

(2012) A. Calcinotto et al.   CANCER RESEARCH

VEGFA-VEGFR Pathway Blockade Inhibits Tumor-Induced Regulatory T-cell Proliferation in Colorectal Cancer

(2012) M. Terme et al.   CANCER RESEARCH

Prognostic significance of T cell subsets in peripheral blood of B cell non-Hodgkin’s lymphoma patients

(2012) Mehdi Dehghani et al.   MEDICAL ONCOLOGY

Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival

(2012) Joffrey Pelletier et al.   Frontiers in Oncology

Molecular Pathways: Hypoxia Response in Immune Cells Fighting or Promoting Cancer

(2011) Asis Palazón et al.   CLINICAL CANCER RESEARCH

Phosphoglycerate kinase 1 a promoting enzyme for peritoneal dissemination in gastric cancer

(2009) Derek Zieker et al.   INTERNATIONAL JOURNAL OF CANCER