4.6 Editorial Material

Historical Perspective of Clinical Nano and Microparticle Formulations for Delivery of Therapeutics

Journal

TRENDS IN MOLECULAR MEDICINE
Volume 27, Issue 6, Pages 516-519

Publisher

CELL PRESS
DOI: 10.1016/j.molmed.2021.04.002

Keywords

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Funding

  1. National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) [R01AI147497]

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Nano and micro-technologies are utilized for therapeutic delivery of biologics and small molecules in formulations of varying sizes. These technologies have unique physiochemical properties that result in improved drug pharmacokinetics and reduced toxicity compared to conventional formulations.
Nano and micro-technologies are used for therapeutic delivery of biologics and small molecules in formulations ranging in size from one nanometer to 100 microns or more. Here we review the unique physiochemical properties of these technologies and how they lead to more beneficial drug pharmacokinetics and toxicity over conventional formulations.

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