Evaluation of inhibitors of intestinal UDP-glucuronosyltransferases 1A8 and 1A10 using raloxifene as a substrate in Caco-2 cells: Studies with four flavonoids of Scutellaria baicalensis

Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression

(2020) Eric P. Allain et al.   BRITISH JOURNAL OF CANCER

Scutellaria baicalensis Georgi. (Lamiaceae): a review of its traditional uses, botany, phytochemistry, pharmacology and toxicology

(2019) Tiantian Zhao et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Potential of herb-drug / herb interactions between substrates and inhibitors of UGTs derived from herbal medicines

(2019) Dan Liu et al.   PHARMACOLOGICAL RESEARCH

Drug metabolizing enzymes and their inhibitors' role in cancer resistance

(2018) Shelly Pathania et al.   BIOMEDICINE & PHARMACOTHERAPY

Simultaneous determination of intestinal permeability and potential drug interactions of complex mixtures using Caco-2 cells and high-resolution mass spectrometry: Studies with Rauwolfia serpentina extract

(2018) Thomas J. Flynn et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis)Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation

(2018) Dan-Dan Tian et al.   DRUG METABOLISM AND DISPOSITION

Transporter-mediated natural product–drug interactions for the treatment of cardiovascular diseases

(2018) Weibin Zha   JOURNAL OF FOOD AND DRUG ANALYSIS

Inhibitory Effects of Baicalein Derived from Japanese Traditional Herbal Medicine on SN-38 Glucuronidation

(2018) Takashi Satoh et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Transporter modulation by Chinese herbal medicines and its mediated pharmacokinetic herb–drug interactions

(2016) Xu Wu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

1-Alpha, 25-dihydroxyvitamin D3 alters the pharmacokinetics of mycophenolic acid in renal transplant recipients by regulating two extrahepatic UDP-glucuronosyltransferases 1A8 and 1A10

(2016) Xiaoliang Wang et al.   Translational Research

Scutellaria baicalensis , the golden herb from the garden of Chinese medicinal plants

(2016) Qing Zhao et al.   Science Bulletin

Flavonoids from Sideritis Species: Human Monoamine Oxidase (hMAO) Inhibitory Activities, Molecular Docking Studies and Crystal Structure of Xanthomicrol

(2015) Fatma Turkmenoglu et al.   MOLECULES

Canagliflozin: A Review of Its Use in Patients with Type 2 Diabetes Mellitus

(2014) Greg L. Plosker   DRUGS

UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib

(2014) H Landmann et al.   Cell Death & Disease

Characterization of Raloxifene Glucuronidation: Potential Role of UGT1A8 Genotype on Raloxifene Metabolism In Vivo

(2013) D. Sun et al.   Cancer Prevention Research

Comparison of Inhibition Capability of Scutellarein and Scutellarin Towards Important Liver UDP-Glucuronosyltransferase (UGT) Isoforms

(2013) Guang-You Ma et al.   PHYTOTHERAPY RESEARCH

Comparative analysis of bioactive phytochemicals from Scutellaria baicalensis, Scutellaria lateriflora, Scutellaria racemosa, Scutellaria tomentosa and Scutellaria wrightii by LC-DAD-MS

(2010) M. Nurul Islam et al.   Metabolomics

Use of Isoform-Specific UGT Metabolism to Determine and Describe Rates and Profiles of Glucuronidation of Wogonin and Oroxylin A by Human Liver and Intestinal Microsomes

(2010) Qiong Zhou et al.   PHARMACEUTICAL RESEARCH

Caco-2 cell monolayers as a tool to study simultaneous phase II metabolism and metabolite efflux of indomethacin, paracetamol and 1-naphthol

(2009) Sanna Siissalo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Comparison of the major flavonoid content of S. baicalensis, S. lateriflora, and their commercial products

(2008) Toshiaki Makino et al.   Journal of Natural Medicines

Flavonoids diosmetin and luteolin inhibit midazolam metabolism by human liver microsomes and recombinant CYP 3A4 and CYP3A5 enzymes

(2007) Luigi Quintieri et al.   BIOCHEMICAL PHARMACOLOGY