Synthesis, antibacterial activities and molecular docking study of thiouracil derivatives containing oxadiazole moiety

Design and Ultrasound Assisted Synthesis of Novel 1,3,4‐Oxadiazole Drugs for Anti‐Cancer Activity

(2020) Priyanka Bhatt et al.   ChemistrySelect

Synthesis of novel of 2, 5-disubstituted 1, 3, 4- oxadiazole derivatives and their in vitro anti-inflammatory, anti-oxidant evaluation, and molecular docking study

(2020) Bharat B. Kashid et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and biological evaluation of 2-(phenoxymethyl)-5-phenyl-1,3,4-oxadiazole derivatives as anti-breast cancer agents

(2019) K. Lakshmithendral et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, in vitro antibacterial and antifungal evaluation of novel 1,3,4-oxadiazole thioether derivatives bearing the 6-fluoroquinazolinylpiperidinyl moiety

(2019) Jun Shi et al.   CHINESE CHEMICAL LETTERS

1,2,4-Oxadiazole as a privileged scaffold for anti-inflammatory and analgesic activities: A complete review.

(2018) Gita Chawla et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Design, synthesis and anti-mycobacterial activity evaluation of benzofuran-isatin hybrids

(2018) Feng Gao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent advances in antimicrobial and bacterial resistance

(2018) Chedly Chouchani et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Design, synthesis and antimicrobial activities of thiouracil derivatives containing triazolo-thiadiazole as SecA inhibitors

(2017) Penglei Cui et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, characterization and molecular docking studies of thiouracil derivatives as potent thymidylate synthase inhibitors and potential anticancer agents

(2017) Abeer M. El-Naggar et al.   MOLECULAR DIVERSITY

Is there a terrible issue with bacterial resistance: pro–con

(2016) D. Raoult et al.   CLINICAL MICROBIOLOGY AND INFECTION

Mechanisms and consequences of bacterial resistance to antimicrobial peptides

(2016) D.I. Andersson et al.   DRUG RESISTANCE UPDATES

Design, syntheses and evaluation of 4-oxo-5-cyano thiouracils as SecA inhibitors

(2015) Arpana S. Chaudhary et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, Synthesis and Evaluation of Triazole-Pyrimidine Analogues as SecA Inhibitors

(2015) Jianmei Cui et al.   ChemMedChem

Vancomycin serum trough concentration vs. clinical outcome in patients with gram-positive infection: a retrospective analysis

(2015) G. Cao et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Mechanisms of Rose Bengal inhibition on SecA ATPase and ion channel activities

(2014) Ying-Hsin Hsieh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fluorescein Analogues Inhibit SecA ATPase: The First Sub-micromolar Inhibitor of Bacterial Protein Translocation

(2012) Ying-Ju Huang et al.   ChemMedChem

Conformer Generation with OMEGA: Learning from the Data Set and the Analysis of Failures

(2012) Paul C. D. Hawkins et al.   Journal of Chemical Information and Modeling

Development of a high-throughput screening assay for the discovery of small-molecule SecA inhibitors

(2011) Kenneth Segers et al.   ANALYTICAL BIOCHEMISTRY

Traffic Jam at the Bacterial Sec Translocase: Targeting the SecA Nanomotor by Small-Molecule Inhibitors

(2011) Kenneth Segers et al.   CHEMISTRY & BIOLOGY

The first low μM SecA inhibitors

(2010) Weixuan Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database

(2010) Paul C. D. Hawkins et al.   Journal of Chemical Information and Modeling

Antibiotics for Emerging Pathogens

(2009) M. A. Fischbach et al.   SCIENCE

The Current State of Multidrug-Resistant Gram-Negative Bacilli in North America

(2008) Anthony M Nicasio et al.   PHARMACOTHERAPY

Protein Translocation Across the Bacterial Cytoplasmic Membrane

(2007) Arnold J.M. Driessen et al.   Annual Review of Biochemistry