An ultrasensitive and point-of-care strategy for enzymes activity detection based on enzyme extends activators to unlock the ssDNase activity of CRISPR/Cas12a (EdU-CRISPR/Cas12a)

Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma

(2019) Devis Pascut et al.   Oncotarget

CRISPR-Cas14 is now part of the artillery for gene editing and molecular diagnostic

(2019) Guillermo Aquino-Jarquin   Nanomedicine-Nanotechnology Biology and Medicine

Electrocatalysis of cerium metal-organic frameworks for ratiometric electrochemical detection of telomerase activity

(2019) Pengfei Dong et al.   BIOSENSORS & BIOELECTRONICS

Detection of DNA 3'-phosphatase activity based on exonuclease III-assisted cascade recycling amplification reaction

(2019) Yuan Zhang et al.   TALANTA

A novel nano-beacon based on DNA functionalized QDs for intracellular telomerase activity monitoring

(2019) Yingxin Ma et al.   SENSORS AND ACTUATORS B-CHEMICAL

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

(2017) Giulia Antoniali et al.   Nature Communications

Nanoscaled Porphyrinic Metal–Organic Frameworks for Electrochemical Detection of Telomerase Activity via Telomerase Triggered Conformation Switch

(2016) Pinghua Ling et al.   ANALYTICAL CHEMISTRY

A cobalt oxyhydroxide nanoflake-based nanoprobe for the sensitive fluorescence detection of T4 polynucleotide kinase activity and inhibition

(2016) Yao Cen et al.   Nanoscale

Human telomerase: biogenesis, trafficking, recruitment, and activation

(2015) Jens C. Schmidt et al.   GENES & DEVELOPMENT

Sensitive and Bidirectional Detection of Urine Telomerase Based on the Four Detection-Color States of Difunctional Gold Nanoparticle Probe

(2014) Ruixue Duan et al.   ANALYTICAL CHEMISTRY

Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk

(2014) Kyle M Walsh et al.   NATURE GENETICS

Ultrasensitive Apurinic/Apyrimidinic Endonuclease 1 Immunosensing Based on Self-Enhanced Electrochemiluminescence of a Ru(II) Complex

(2013) Ying Zhuo et al.   ANALYTICAL CHEMISTRY

Correction: Specific Inhibition of the Redox Activity of Ape1/Ref-1 by E3330 Blocks Tnf-Α-Induced Activation of Il-8 Production in Liver Cancer Cell Lines

(2013) Laura Cesaratto et al.   PLoS One

Apurinic/apyrimidinic endonuclease 1, the sensitive marker for DNA deterioration in dextran sulfate sodium-induced acute colitis

(2013) In-Youb Chang et al.   REDOX REPORT

Genetic Screening for Synthetic Lethal Partners of Polynucleotide Kinase/Phosphatase: Potential for Targeting SHP-1-Depleted Cancers

(2012) T. R. Mereniuk et al.   CANCER RESEARCH

Oxidative genome damage and its repair: Implications in aging and neurodegenerative diseases

(2012) Muralidhar L. Hegde et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Insights into the biomedical effects of carboxylated single-wall carbon nanotubes on telomerase and telomeres

(2012) Yong Chen et al.   Nature Communications

Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA

(2011) Yan Xu   CHEMICAL SOCIETY REVIEWS

Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair

(2011) Nasser Tahbaz et al.   NUCLEIC ACIDS RESEARCH