New IVIVE method for the prediction of total human clearance and relative elimination pathway contributions from in vitro hepatocyte and microsome data

Title
New IVIVE method for the prediction of total human clearance and relative elimination pathway contributions from in vitro hepatocyte and microsome data
Authors
Keywords
Extended Clearance Concept Classification System (ECCCS), Clearance prediction, Hepatic uptake, In vitro–in vivo, extrapolation (IVIVE)
Journal
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 86, Issue -, Pages 96-102
Publisher
Elsevier BV
Online
2016-03-04
DOI
10.1016/j.ejps.2016.02.022

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