Direct coordination of pterin to FeII enables neurotransmitter biosynthesis in the pterin-dependent hydroxylases

NRVS Studies of the Peroxide Shunt Intermediate in a Rieske Dioxygenase and Its Relation to the Native FeII O2 Reaction

(2018) Kyle D. Sutherlin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nuclear Resonance Vibrational Spectroscopy Definition of O2 Intermediates in an Extradiol Dioxygenase: Correlation to Crystallography and Reactivity

(2018) Kyle D. Sutherlin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants

(2017) Subhasree Kal et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Visualizing the Reaction Cycle in an Iron(II)- and 2-(Oxo)-glutarate-Dependent Hydroxylase

(2017) Andrew J. Mitchell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

O2 Activation by Non-Heme Iron Enzymes

(2016) Edward I. Solomon et al.   BIOCHEMISTRY

Kinetic Mechanism of Phenylalanine Hydroxylase: Intrinsic Binding and Rate Constants from Single-Turnover Experiments

(2013) Kenneth M. Roberts et al.   BIOCHEMISTRY

Pulsed EPR Study of Amino Acid and Tetrahydropterin Binding in a Tyrosine Hydroxylase Nitric Oxide Complex: Evidence for Substrate Rearrangements in the Formation of the Oxygen-Reactive Complex

(2013) Matthew D. Krzyaniak et al.   BIOCHEMISTRY

Elucidation of the Fe(iv)=O intermediate in the catalytic cycle of the halogenase SyrB2

(2013) Shaun D. Wong et al.   NATURE

Electronic Structure Analysis of the Oxygen-Activation Mechanism by FeII- and α-Ketoglutarate (αKG)-Dependent Dioxygenases

(2012) Shengfa Ye et al.   CHEMISTRY-A EUROPEAN JOURNAL

Activation of α-Keto Acid-Dependent Dioxygenases: Application of an {FeNO}7/{FeO2}8Methodology for Characterizing the Initial Steps of O2Activation

(2011) Adrienne R. Diebold et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single Turnover Kinetics of Tryptophan Hydroxylase: Evidence for a New Intermediate in the Reaction of the Aromatic Amino Acid Hydroxylases

(2010) Jorge Alex Pavon et al.   BIOCHEMISTRY

Spectroscopy and Kinetics of Wild-Type and Mutant Tyrosine Hydroxylase: Mechanistic Insight into O2Activation

(2009) Marina S. Chow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expression, Purification and Enzymatic Characterization of the Catalytic Domains of Human Tryptophan Hydroxylase Isoforms

(2009) Michael S. Windahl et al.   PROTEIN JOURNAL