SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

(2020) Yixuan J. Hou et al.   CELL

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China

(2020) Shaobo Shi et al.   JAMA Cardiology

Betacoronavirus Genomes: How Genomic Information has been Used to Deal with Past Outbreaks and the COVID-19 Pandemic

(2020) Alejandro Llanes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases

(2020) Diana Lindner et al.   JAMA Cardiology

Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV.

(2020) Kumari G. Lokugamage et al.   JOURNAL OF VIROLOGY

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

(2020) Lisa Miorin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

(2020) Qian Zhang et al.   SCIENCE

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

(2020) Paul Bastard et al.   SCIENCE

Evasion of Type I Interferon by SARS-CoV-2

(2020) Hongjie Xia et al.   Cell Reports

Genetic mechanisms of critical illness in Covid-19

(2020) Erola Pairo-Castineira et al.   NATURE

Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection

(2019) Courtney E. Comar et al.   mBio

Double-Stranded RNA Sensors and Modulators in Innate Immunity

(2019) Sun Hur   Annual Review of Immunology

Zika virus production is resistant to RNase L antiviral activity

(2019) Jillian N Whelan et al.   JOURNAL OF VIROLOGY

Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and Type III Interferons

(2019) Adriana Forero et al.   IMMUNITY

Innate Immune Evasion by Human Respiratory RNA Viruses

(2019) Marjolein Kikkert   Journal of Innate Immunity

Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells

(2019) Anjali Jacob et al.   Nature Protocols

Activation of RNase L in Egyptian Rousette Bat-Derived RoNi/7 Cells Is Dependent Primarily on OAS3 and Independent of MAVS Signaling

(2019) Yize Li et al.   mBio

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection

(2018) Javier Canton et al.   PLoS Pathogens

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

(2017) Ioanna E. Galani et al.   IMMUNITY

Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line

(2017) Yize Li et al.   eLife

Clinicopathologic, Immunohistochemical, and Ultrastructural Findings of a Fatal Case of Middle East Respiratory Syndrome Coronavirus Infection in the United Arab Emirates, April 2014

(2016) Dianna L. Ng et al.   AMERICAN JOURNAL OF PATHOLOGY

Antagonism of RNase L Is Required for Murine Coronavirus Replication in Kupffer Cells and Liver Sinusoidal Endothelial Cells but Not in Hepatocytes

(2016) Yize Li et al.   JOURNAL OF VIROLOGY

Activation of RNase L by Murine Coronavirus in Myeloid Cells Is Dependent on BasalOasGene Expression and Independent of Virus-Induced Interferon

(2016) L. Dillon Birdwell et al.   JOURNAL OF VIROLOGY

Viral Load Kinetics of MERS Coronavirus Infection

(2016) Myoung-don Oh et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses

(2016) Yize Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation

(2016) Joshua M. Thornbrough et al.   mBio

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

(2016) Huib H. Rabouw et al.   PLoS Pathogens

RNase L Activates the NLRP3 Inflammasome during Viral Infections

(2015) Arindam Chakrabarti et al.   Cell Host & Microbe

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Continuous and Discontinuous RNA Synthesis in Coronaviruses

(2015) Isabel Sola et al.   Annual Review of Virology

Bitter and sweet taste receptors regulate human upper respiratory innate immunity

(2014) Robert J. Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

An Important Role for Type III Interferon (IFN- /IL-28) in TLR-Induced Antiviral Activity

(2014) N. Ank et al.   JOURNAL OF IMMUNOLOGY

Cell-Type-Specific Effects of RNase L on Viral Induction of Beta Interferon

(2014) S. Banerjee et al.   mBio

Targeting Membrane-Bound Viral RNA Synthesis Reveals Potent Inhibition of Diverse Coronaviruses Including the Middle East Respiratory Syndrome Virus

(2014) Anna Lundin et al.   PLoS Pathogens

Innate Immune Response of Human Alveolar Type II Cells Infected with Severe Acute Respiratory Syndrome–Coronavirus

(2013) Zhaohui Qian et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

ORF7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN- -induced antiviral response

(2013) A. Dedeurwaerder et al.   JOURNAL OF GENERAL VIROLOGY

Cell-Type-Specific Activation of the Oligoadenylate Synthetase-RNase L Pathway by a Murine Coronavirus

(2013) L. Zhao et al.   JOURNAL OF VIROLOGY

Antagonism of the Interferon-Induced OAS-RNase L Pathway by Murine Coronavirus ns2 Protein Is Required for Virus Replication and Liver Pathology

(2012) Ling Zhao et al.   Cell Host & Microbe

PKR-Dependent Inflammatory Signals

(2012) R. Kang et al.   Science Signaling

Cell-Type-Specific Type I Interferon Antagonism Influences Organ Tropism of Murine Coronavirus

(2011) L. Zhao et al.   JOURNAL OF VIROLOGY

Coronavirus Gene 7 Counteracts Host Defenses and Modulates Virus Virulence

(2011) Jazmina L. G. Cruz et al.   PLoS Pathogens

Murine Coronavirus Receptors Are Differentially Expressed in the Central Nervous System and Play Virus Strain-Dependent Roles in Neuronal Spread

(2010) S. J. Bender et al.   JOURNAL OF VIROLOGY

Accessory Protein 5a Is a Major Antagonist of the Antiviral Action of Interferon against Murine Coronavirus

(2010) C. A. Koetzner et al.   JOURNAL OF VIROLOGY

Proteolytic Activation of the Spike Protein at a Novel RRRR/S Motif Is Implicated in Furin-Dependent Entry, Syncytium Formation, and Infectivity of Coronavirus Infectious Bronchitis Virus in Cultured Cells

(2009) Y. Yamada et al.   JOURNAL OF VIROLOGY

Coronaviruses post-SARS: update on replication and pathogenesis

(2009) Stanley Perlman et al.   NATURE REVIEWS MICROBIOLOGY

Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites

(2009) S. Belouzard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Severe Acute Respiratory Syndrome Coronavirus Triggers Apoptosis via Protein Kinase R but Is Resistant to Its Antiviral Activity

(2008) V. Krahling et al.   JOURNAL OF VIROLOGY

Murine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia

(2008) J. K. Roth-Cross et al.   JOURNAL OF VIROLOGY

SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic Reticulum

(2008) Kèvin Knoops et al.   PLOS BIOLOGY