Review
Entomology
Erin M. Borland, Rebekah C. Kading
Summary: Identifying the source of vertebrate blood in blood-feeding arthropod vectors is crucial for understanding pathogen transmission dynamics, and significant advancements have been made in the past decade. New technologies offer novel approaches to bloodmeal analysis, while miniaturization engineering has facilitated field deployment. Technical challenges remain, particularly in preventing sample degradation.
Article
Chemistry, Multidisciplinary
Jung Min Lee, Dingchang Lin, Guosong Hong, Kyoung-Ho Kim, Hong-Gyu Park, Charles M. Lieber
Summary: This study demonstrates the high-performance neural recording ability of double-sided three-dimensional (3D) electrodes, which show significant improvements in neuron quantity, spike amplitude, and signal-to-noise ratio compared to standard two-dimensional electrodes. These 3D electrodes also enable stable detection of single-neuron activity over extended periods of time.
Review
Parasitology
Jackson M. Muema, Joel L. Bargul, Meshack A. Obonyo, Sospeter N. Njeru, Damaris Matoke-Muhia, James M. Mutunga
Summary: An integrated approach to combating arthropod-borne diseases involves using natural compounds to design interventions that can block pathogen transmission. This review explores the potential of natural compounds in inhibiting the transmission of human pathogens and proposes translational strategies for disease control interventions.
PARASITES & VECTORS
(2022)
Article
Computer Science, Interdisciplinary Applications
Xiaoping Liang, Hualong Yang, Qiong Wu
Summary: This paper investigates the problem of online crowdsourced delivery using private cars in urban areas. Various practical factors such as time-dependent travel times, private car detours and distribution, and retail stores as delivery or transfer nodes are considered. A mixed-integer programming model is proposed to maximize the total profit, and an improved adaptive large neighbourhood search algorithm is designed to solve the problem. Experimental results demonstrate the effectiveness and applicability of the proposed algorithm, and numerical experiments on a large-scale delivery network validate the benefits of well-planned online crowdsourced delivery.
COMPUTERS & INDUSTRIAL ENGINEERING
(2022)
Article
Cell Biology
Sydney Song, Brianna Regan, Evon S. Ereifej, E. Ricky Chan, Jeffrey R. Capadona
Summary: This study aims to understand the neuroinflammatory response to intracortical microelectrodes and its impact on device performance. By investigating gene expression changes, potential therapeutic targets that can improve device performance were identified.
Review
Biochemistry & Molecular Biology
Valeria Zeni, Georgia V. Baliota, Giovanni Benelli, Angelo Canale, Christos G. Athanassiou
Summary: The use of diatomaceous earths (DEs) in Integrated Pest Management (IPM) programs shows significant promise in controlling a wide range of arthropod pests. DEs, a naturally occurring sedimentary rock composed of fossilized diatoms, have been effective in controlling stored product pests and some household insects in dry environments. Challenges related to the real-world applications and adoption of DEs in IPM protocols are also discussed.
Article
Multidisciplinary Sciences
Yasutoshi Jimbo, Daisuke Sasaki, Takashi Ohya, Sunghoon Lee, Wonryung Lee, Faezeh Arab Hassani, Tomoyuki Yokota, Katsuhisa Matsuura, Shinjiro Umezu, Tatsuya Shimizu, Takao Someya
Summary: An organic electrochemical transistor (OECT) matrix is shown for intracellular action potential recording, where the driving voltage simultaneously causes electroporation. The recorded peak amplitudes were larger than extracellular field potential recording, and could be further enhanced by tuning the driving voltage and OECT geometry. Miniaturization and multiplexed recording capabilities were demonstrated through a 4 x 4 action potential mapping using a matrix of 5- x 5-mu m(2) OECTs, realized with a mild fabrication process and simple circuit without limiting potential applications of organic electronics.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Review
Environmental Sciences
David Cubides, Xavier Guimera, Irene Jubany, Xavier Gamisans
Summary: Nitrogen oxides (NOx), including nitrogen monoxide (NO) and nitrogen dioxide (NO2), are important global atmospheric pollutants with adverse impacts on human respiratory health, animals, and the environment. Biotechnologies used for wastewater treatment are being investigated as potential solutions for NOx treatment. This review summarizes the current state of these biotechnologies, discusses different microorganisms, and analyzes the performance of bio-reactors for NOx emission control, providing an overview of technical solutions and challenges.
Article
Chemistry, Multidisciplinary
Dongxin Xu, Jiaru Fang, Hao Wang, Xinwei Wei, Jinhu Yang, Hongbo Li, Tao Yang, Ying Li, Chuan Liu, Ning Hu
Summary: In this study, a nanotrapped microelectrode based on a porous PET membrane was developed to improve cell-electrode coupling and intracellular recording performance. The nanotraps and nanoedge structure enhance the protrusion of the cell membrane and provide effective electroporation, allowing for longer intracellular access and consecutive electroporation events.
Article
Parasitology
Eileen H. Jeffrey Gutierrez, M. A. Riehle, K. R. Walker, K. C. Ernst, G. Davidowitz
Summary: This study examines the utility of using body size as an entomological index to monitor the age structure of Aedesaegypti mosquitoes. The results show that body size itself is not significantly associated with age, but temperature, body size, female abundance, and relative humidity have a significant impact on age. Additionally, the study finds that age variation is greater within cities than between cities.
PARASITES & VECTORS
(2022)
Article
Immunology
Milehna Mara Guarido, Thopisang Motlou, Megan A. Riddin, Caitlin MacIntyre, Sontaga Cris Manyana, Todd Johnson, Maarten Schrama, Erin E. Gorsich, Basil D. Brooke, A. Paulo G. Almeida, Marietjie Venter
Summary: Research shows that Shuni virus is linked to neurological and febrile illnesses in both animals and humans, with potential vectors being species of the genera Mansonia, Culex, Aedes, and Anopheles. The presence of this virus in mosquitoes suggests a possible association with outbreaks in Africa and potential emergence in other regions.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Chemistry, Multidisciplinary
Jiaru Fang, Dongxin Xu, Hao Wang, Jin Wu, Ying Li, Tao Yang, Chuan Liu, Ning Hu
Summary: Electrophysiology is a unique biomarker for disease investigation or drug assessment in electrogenic cells. Vertical nanoelectrode arrays have been successful in achieving high-quality intracellular electrophysiological study in electrogenic cells. However, achieving high success rate and high-quality, long-term intracellular recording using inexpensive nanostructures remains a challenge. In this study, a scalable and robust hollow nanopillar electrode was developed to enhance intracellular recording of cardiomyocytes. Regulation of the nanostructure geometry proved to be a powerful strategy in enhancing intracellular recording.
Article
Biodiversity Conservation
Achyut Kumar Banerjee, Tien Ming Lee, Hui Feng, Xinru Liang, Yuting Lin, Jiakai Wang, Minghui Yin, Hao Peng, Yelin Huang
Summary: Internet trade in China's online market is identified as a major dispersal pathway for non-native plant species. Invasive species dominate the online marketplace, and there is a lack of effective regulations to manage this trade. The study suggests the integration of a standardized risk assessment framework and continuous surveillance to strengthen trading regulations and take proactive management measures.
CONSERVATION BIOLOGY
(2023)
Article
Veterinary Sciences
Alexander P. Douglass, Luke O'Grady, Guy McGrath, Jamie Tratalos, John F. Mee, Damien Barrett, Cosme Sanchez-Miguel, Simon J. More, Aurelien Madouasse, Martin Green, Jamie M. Madden, Conor G. McAloon
Summary: In the last fifteen years, emerging vector-borne diseases have posed a significant threat to cattle in Europe. To detect outbreaks early, a syndromic surveillance system based on non-specific disease indicators is proposed. This study developed a system for monitoring Irish dairy herds using milk recording and meteorological data, which was able to detect the Schmallenberg virus (SBV) incursion earlier than conventional surveillance methods.
PREVENTIVE VETERINARY MEDICINE
(2022)
Article
Multidisciplinary Sciences
Jean Baptiste Yaro, Alfred B. Tiono, Alphonse Ouedraogo, Ben Lambert, Z. Amidou Ouedraogo, Amidou Diarra, Adama Traore, Malik Lankouande, Issiaka Soulama, Antoine Sanou, Eve Worrall, Efundem Agboraw, N'Fale Sagnon, Hilary Ranson, Thomas S. Churcher, Steve W. Lindsay, Anne L. Wilson
Summary: Burkina Faso has a high burden of malaria despite the implementation of malaria control measures. A study conducted in the country found that malaria infections were highest in children aged 5 to 15 years, despite the use of insecticide-treated nets. The study also showed that administering seasonal malaria chemoprevention to children aged 10 and 15 could significantly reduce malaria cases.
SCIENTIFIC REPORTS
(2022)
Letter
Veterinary Sciences
Kayleigh M. Hansford, Emma L. Gillingham, Ben Cull, Liz McGinley, Jolyon M. Medlock, L. Paul Phipps, Martin Peaty
Article
Infectious Diseases
Kayleigh M. Hansford, Daniel Carter, Emma L. Gillingham, Luis M. Hernandez-Triana, John Chamberlain, Benjamin Cull, Liz McGinley, L. Paul Phipps, Jolyon M. Medlock
TICKS AND TICK-BORNE DISEASES
(2019)
Article
Entomology
A. G. C. Vaux, T. Dallimore, B. Cull, F. Schaffner, C. Strode, V Pflueger, A. Murchie, I Rea, Z. Newham, L. Mcginley, M. Catton, E. L. Gillingham, J. M. Medlock
MEDICAL AND VETERINARY ENTOMOLOGY
(2019)
Article
Public, Environmental & Occupational Health
Benjamin Cull, Maaike E. Pietzsch, Emma L. Gillingham, Liz McGinley, Jolyon M. Medlock, Kayleigh M. Hansford
ZOONOSES AND PUBLIC HEALTH
(2020)
Article
Infectious Diseases
Emma L. Gillingham, Kayleigh M. Hansford, Scott Meadows, Julia Henney, Filip Wieckowski, Luis M. Hernandez-Triana, Ivan Muscat, Joseph Muscat, Clara Beckert, Nadya Nikolova, Ben Cull, Jolyon M. Medlock
TICKS AND TICK-BORNE DISEASES
(2020)
Article
Virology
Rhys Parry, Fanny Naccache, El Hadji Ndiaye, Gamou Fall, Ilaria Castelli, Renke Luehken, Jolyon Medlock, Benjamin Cull, Jenny C. Hesson, Fabrizio Montarsi, Anna-Bella Failloux, Alain Kohl, Esther Schnettler, Mawlouth Diallo, Sassan Asgari, Isabelle Dietrich, Stefanie C. Becker
Article
Entomology
B. Cull, K. M. Hansford, L. McGinley, E. L. Gillingham, A. G. C. Vaux, R. Smith, J. M. Medlock
Summary: This study investigated the variation in Borrelia burgdorferi s.l. infection rates in Ixodes ricinus ticks across 24 field sites in England and Wales, showing site-specific and year-to-year differences. The main genospecies detected was B. garinii, highlighting the spatial and temporal variability in infected tick bites in areas used for outdoor activities in England and Wales.
MEDICAL AND VETERINARY ENTOMOLOGY
(2021)
Article
Microbiology
Xin-Ru Wang, Nicole Y. Burkhardt, Timothy J. Kurtti, Jonathan D. Oliver, Lisa D. Price, Benjamin Cull, Cody J. Thorpe, Michalina Silva Thiel, Ulrike G. Munderloh
Summary: This study reveals that apoptosis plays a crucial role in rickettsial infection and replication in tick cells, with no direct correlation between apoptosis activation and rickettsial pathogenicity in vector cells. These findings provide insights into the mechanisms of how apoptosis facilitates rickettsial infection in arthropod vectors, contributing to the potential discovery of targets for new vaccines and drugs against rickettsial infections.
Article
Microbiology
Antonio Luis de O. A. Petersen, Benjamin Cull, Beatriz R. S. Dias, Luana C. Palma, Yasmin da S. Luz, Juliana P. B. de Menezes, Jeremy C. Mottram, Patricia S. T. Veras
Summary: The Hsp90 inhibitor 17-AAG was shown to cause abnormal activation of the autophagic pathway, leading to the formation of immature autophagosomes and subsequent parasite death. This study provides evidence of the role of autophagy in 17-AAG-induced cell death, supporting the potential of Hsp90 as a drug target for parasitic diseases.
Article
Veterinary Sciences
Benjamin Cull, Nicole Y. Burkhardt, Xin-Ru Wang, Cody J. Thorpe, Jonathan D. Oliver, Timothy J. Kurtti, Ulrike G. Munderloh
Summary: This study found that the endosymbiont Rickettsia buchneri in ticks can inhibit the infection and replication of tick-borne pathogens. The presence of R. buchneri was observed to reduce the growth of R. parkeri by a significant percentage in tick cells. This research suggests a potential role of R. buchneri in preventing other rickettsiae from colonizing ticks and being transmitted transovarially, which could have important implications for understanding rickettsial competition and vector competence.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Entomology
Jolyon M. Medlock, Alexander G. C. Vaux, Sara Gandy, Benjamin Cull, Liz McGinley, Emma Gillingham, Matthew Catton, Steven T. Pullan, Kayleigh M. Hansford
Summary: This study investigated the density of Borrelia burgdorferi-infected Ixodes ricinus nymphs (DIN) across a Lyme disease-endemic landscape in southern England from 2013-2017. The results showed variations in nymph density (DON), nymph infection prevalence (NIP), and DIN across different natural habitats, with the highest DIN in woodland edge and high biodiversity woodlands. The study also discussed the potential impacts of scrub vegetation and bird/gamebirds on tick infection rates.
MEDICAL AND VETERINARY ENTOMOLOGY
(2022)
Article
Entomology
Benjamin Cull
Summary: This study evaluated the use of the online image-based biological recording platform iNaturalist to monitor the distributions of tick species in the United States and Canada. The observations on iNaturalist accurately represented the distributions and seasonality of the studied tick species, and highlighted potential new areas of tick expansion. This supports the use of iNaturalist data as a cost-effective tool for passive tick surveillance.
Article
Environmental Sciences
Emma L. Gillingham, Benjamin Cull, Maaike E. Pietzsch, L. Paul Phipps, Jolyon M. Medlock, Kayleigh Hansford
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2020)
Article
Multidisciplinary Sciences
Hein Sprong, Manoj Fonville, Arieke Docters van Leeuwen, Elodie Devillers, Adolfo Ibanez-Justicia, Arjan Stroo, Kayleigh Hansford, Benjamin Cull, Jolyon Medlock, Paul Heyman, Christel Cochez, Lisa Weis, Cornelia Silaghi, Sara Moutailler