Iron enhances the binding rates and translational efficiency of iron responsive elements (IREs) mRNA with initiation factor eIF4F

Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA

(2020) Peiyuan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloids: Regulators of Metal Homeostasis in the Synapse

(2020) Masahiro Kawahara et al.   MOLECULES

Nucleic Acid–Based Therapeutics for Parkinson’s Disease

(2019) Masayuki Nakamori et al.   Neurotherapeutics

Targeting the Iron-Response Elements of the mRNAs for the Alzheimer’s Amyloid Precursor Protein and Ferritin to Treat Acute Lead and Manganese Neurotoxicity

(2019) Jack Rogers et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Relevance of the iron-responsive element (IRE) pseudotriloop structure for IRP1/2 binding and validation of IRE-like structures using the yeast three-hybrid system

(2019) Shih-Cheng Chen et al.   GENE

Increased Dynamics of α-Synuclein Fibrils by β-Synuclein Leads to Reduced Seeding and Cytotoxicity

(2019) Xue Yang et al.   Scientific Reports

Kinetic analyses of phosphorylated and non-phosphorylated eIFiso4E binding to mRNA cap analogues

(2018) Mateen A. Khan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Poly (A) binding protein enhances the binding affinity of potyvirus VPg to eukaryotic initiation factor eIF4F and activates in vitro translation

(2018) Mateen A. Khan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Phosphorylation of translation initiation factor eIFiso4E promotes translation through enhanced binding to potyvirus VPg

(2018) Mateen A Khan   JOURNAL OF BIOCHEMISTRY

Thermodynamic and Kinetic Analyses of Iron Response Element (IRE)-mRNA Binding to Iron Regulatory Protein, IRP1

(2017) Mateen A. Khan et al.   Scientific Reports

Iron regulation of hepcidin through Hfe and Hjv: Common or distinct pathways?

(2015) Kostas Pantopoulos   HEPATOLOGY

The role of iron in brain ageing and neurodegenerative disorders

(2014) Roberta J Ward et al.   LANCET NEUROLOGY

Rapid kinetics of iron responsive element (IRE) RNA/iron regulatory protein 1 and IRE-RNA/eIF4F complexes respond differently to metal ions

(2014) Mateen A. Khan et al.   NUCLEIC ACIDS RESEARCH

The physiological functions of iron regulatory proteins in iron homeostasis - an update

(2014) De-Liang Zhang et al.   Frontiers in Pharmacology

Fe2+ binds iron responsive element-RNA, selectively changing protein-binding affinities and regulating mRNA repression and activation

(2012) J. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accommodating variety in iron-responsive elements: Crystal structure of transferrin receptor 1 B IRE bound to iron regulatory protein 1

(2011) William E. Walden et al.   FEBS LETTERS

Direct Fe2+Sensing by Iron-responsive Messenger RNA·Repressor Complexes Weakens Binding

(2009) Mateen A. Khan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY