4.6 Article

O group is a protective factor for COVID19 in Basque population

Journal

PLOS ONE
Volume 16, Issue 4, Pages -

Publisher

PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0249494

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Funding

  1. Instituto de Salud Carlos III [COV20/00314]
  2. European Support (FEDER)

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The ABO blood group has been found to be related to COVID19 infection, with group O showing a protective effect against the disease while groups A, B, and AB are risk factors. The distribution of ABO blood groups varies slightly among populations, necessitating replication of results in specific areas with proper control populations.
ABO blood groups have recently been related to COVID19 infection. In the present work, we performed this analysis using data from 412 COVID19 patients and 17796 blood donors, all of them from Gipuzkoa, a region in Northern Spain. The results obtained confirmed this relation, in addition to showing a clear importance of group O as a protective factor in COVID19 disease, with an OR = 0.59 (CI95% 0.481-0.7177, p<0.0001) while A, B and AB are risk factors. ABO blood groups are slightly differently distributed in the populations and therefore these results should be replicated in the specific areas with a proper control population.

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