Targeting HIF-1α by newly synthesized Indolephenoxyacetamide (IPA) analogs to induce anti-angiogenesis-mediated solid tumor suppression

Patient-derived xenografts of different grade gliomas retain the heterogeneous histological and genetic features of human gliomas

(2020) Wenxin Zeng et al.   Cancer Cell International

Indole alkaloids with potential anticancer activity

(2020) Dan Xu et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Targeting hypoxia-inducible factor-1, for cancer treatment: Recent advances in developing small-molecule inhibitors from natural compounds

(2020) Zhaowu Ma et al.   SEMINARS IN CANCER BIOLOGY

Molecular docking and synthesis of caffeic acid analogous and its anti-inflammatory, analgesic and ulcerogenic studies

(2020) Fares Hezam Al-Ostoot et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones

(2019) Monica Demurtas et al.   BIOORGANIC CHEMISTRY

Molecular Structure, DFT, Vibrational Spectra with Fluorescence Effect, Hirshfeld Surface, Docking Simulation and Antioxidant Activity of Thiazole Derivative

(2019) Hussien A. Khamees et al.   ChemistrySelect

Synthesis, molecular docking, and apoptogenic efficacy of novel N-heterocycle analogs to target B-cell lymphoma 2/X-linked inhibitors of apoptosis proteins to regress melanoma

(2019) Zabiulla Zabiulla et al.   MEDICINAL CHEMISTRY RESEARCH

Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity

(2019) Shinichiro Fuse et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design-based synthesis, molecular docking analysis of an anti-inflammatory drug, and geometrical optimization and interaction energy studies of an indole acetamide derivative

(2019) Fares Hezam Al-Ostoot et al.   JOURNAL OF MOLECULAR STRUCTURE

BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation

(2016) Prabhu Thirusangu et al.   ANGIOGENESIS

The latex sap of the ‘Old World Plant’ Lagenaria siceraria with potent lectin activity mitigates neoplastic malignancy targeting neovasculature and cell death

(2016) V. Vigneshwaran et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Antiangiogenic cancer treatment: The great discovery and greater complexity (Review)

(2016) Ewa Maj et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Hypoxia-Inducible Factor-1 in Physiological and Pathophysiological Angiogenesis: Applications and Therapies

(2015) Agnieszka Zimna et al.   Biomed Research International

New role of lupeol in reticence of angiogenesis, the cellular parameter of neoplastic progression in tumorigenesis models through altered gene expression

(2014) B.R. Vijay Avin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DAO-9 (2,5-di(4-aryloylaryloxymethyl)-1,3,4-oxadiazole) exhibits p53 induced apoptogenesis through caspase-3 mediated endonuclease activity in murine carcinoma

(2014) H.D. Gurupadaswamy et al.   BIOMEDICINE & PHARMACOTHERAPY

Synthesis and tumor inhibitory activity of novel coumarin analogs targeting angiogenesis and apoptosis

(2014) B.R. Vijay Avin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hypoxia-Inducible Factor 1 and Cardiovascular Disease

(2013) Gregg L. Semenza   Annual Review of Physiology

Synthesis, angiopreventive activity, and in vivo tumor inhibition of novel benzophenone–benzimidazole analogs

(2013) V. Lakshmi Ranganatha et al.   LIFE SCIENCES

InCl3 mediated one-pot multicomponent synthesis, anti-microbial, antioxidant and anticancer evaluation of 3-pyranyl indole derivatives

(2010) Neelakandan Vidhya Lakshmi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Metal complexes involving indole rings: Structures and effects of metal–indole interactions

(2008) Yuichi Shimazaki et al.   COORDINATION CHEMISTRY REVIEWS

Evaluation of serum vascular endothelial growth factor (VEGF) and microvessel density (MVD) as prognostic indicators in carcinoma breast

(2008) S. Shivakumar et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY