Development of E1224 by leveraging a strategic partnership for the medicines creation against neglected tropical diseases

Advances in preclinical approaches to Chagas disease drug discovery

(2019) Fernando Villalta et al.   Expert Opinion on Drug Discovery

Outcome of E1224-Benznidazole Combination Treatment for Infection with a Multidrug-Resistant Trypanosoma cruzi Strain in Mice

(2018) Lívia de Figueiredo Diniz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro and In Vivo Evaluation of the Antifungal Activity of APX001A/APX001 against Candida auris

(2018) Christopher L. Hager et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial

(2018) Faustino Torrico et al.   LANCET INFECTIOUS DISEASES

Efficacy and safety of fosravuconazole L-lysine ethanolate, a novel oral triazole antifungal agent, for the treatment of onychomycosis: A multicenter, double-blind, randomized phase III study

(2018) Shinichi Watanabe et al.   JOURNAL OF DERMATOLOGY

Development and Distribution of Drugs for NTDs: Efforts of One Pharmaceutical Company

(2016) Makoto Asada   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Randomized Trial of Posaconazole and Benznidazole for Chronic Chagas' Disease

(2014) Israel Molina et al.   NEW ENGLAND JOURNAL OF MEDICINE

Madurella mycetomatis Is Highly Susceptible to Ravuconazole

(2014) Sarah Abdalla Ahmed et al.   PLoS Neglected Tropical Diseases

In VitroAntifungal Activity of Isavuconazole against Madurella mycetomatis

(2012) Wendy Kloezen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroSusceptibility ofMadurella mycetomatisto Posaconazole and Terbinafine

(2011) Alex van Belkum et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efficacy of Oral E1210, a New Broad-Spectrum Antifungal with a Novel Mechanism of Action, in Murine Models of Candidiasis, Aspergillosis, and Fusariosis

(2011) Katsura Hata et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroActivity of E1210, a Novel Antifungal, against Clinically Important Yeasts and Molds

(2011) Mamiko Miyazaki et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

E1210, a New Broad-Spectrum Antifungal, Suppresses Candida albicans Hyphal Growth through Inhibition of Glycosylphosphatidylinositol Biosynthesis

(2011) Nao-aki Watanabe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Madurella mycetomatis Is Not Susceptible to the Echinocandin Class of Antifungal Agents

(2010) W. W. J. van de Sande et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY