FOXO3 is a latent tumor suppressor for FOXO3-positive and cytoplasmic-type gastric cancer cells

AQP5 enriches for stem cells and cancer origins in the distal stomach

(2020) Si Hui Tan et al.   NATURE

FOXO transcription factor family in cancer and metastasis

(2020) Yannasittha Jiramongkol et al.   CANCER AND METASTASIS REVIEWS

NF-κB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells

(2019) Kanae Echizen et al.   ONCOGENE

FoxO3 activation in hypoxic tubules prevents chronic kidney disease

(2019) Ling Li et al.   JOURNAL OF CLINICAL INVESTIGATION

FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression

(2018) Marten Hornsveld et al.   CANCER RESEARCH

Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries

(2018) Claudia Allemani et al.   LANCET

Re-evaluating the role of FOXOs in cancer

(2018) M. Hornsveld et al.   SEMINARS IN CANCER BIOLOGY

Critical role of FOXO3a in carcinogenesis

(2018) Ying Liu et al.   Molecular Cancer

Inflammation in gastric cancer: Interplay of the COX-2/prostaglandin E2and Toll-like receptor/MyD88 pathways

(2016) Kanae Echizen et al.   CANCER SCIENCE

Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer

(2016) M Hornsveld et al.   CELL DEATH AND DIFFERENTIATION

Gastric cancer

(2016) Eric Van Cutsem et al.   LANCET

Evolutionary Acquisition of Cysteines Determines FOXO Paralog-Specific Redox Signaling

(2015) Marrit Putker et al.   ANTIOXIDANTS & REDOX SIGNALING

FOXO transcription factors in cancer development and therapy

(2015) Alexandra Coomans de Brachène et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genetics and Molecular Pathogenesis of Gastric Adenocarcinoma

(2015) Patrick Tan et al.   GASTROENTEROLOGY

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Comprehensive molecular characterization of gastric adenocarcinoma

(2014) Adam J. Bass et al.   NATURE

FOXO3 expression during colorectal cancer progression: biomarker potential reflects a tumour suppressor role

(2013) M D Bullock et al.   BRITISH JOURNAL OF CANCER

FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells

(2013) Hyeonju Yeo et al.   EMBO JOURNAL

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Decreased Expression of the FOXO3a Gene Is Associated with Poor Prognosis in Primary Gastric Adenocarcinoma Patients

(2013) Xiao-bo Yang et al.   PLoS One

Inhibition of PI3K/mTOR Leads to Adaptive Resistance in Matrix-Attached Cancer Cells

(2012) Taru Muranen et al.   CANCER CELL

β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer

(2012) Stephan P Tenbaum et al.   NATURE MEDICINE

Wnt5a Potentiates TGF-  Signaling to Promote Colonic Crypt Regeneration After Tissue Injury

(2012) H. Miyoshi et al.   SCIENCE

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth

(2011) Takatsugu Ishimoto et al.   CANCER CELL

Activation of epidermal growth factor receptor signaling by the prostaglandin E2 receptor EP4 pathway during gastric tumorigenesis

(2011) Hiroko Oshima et al.   CANCER SCIENCE

Prostaglandin E2 Signaling and Bacterial Infection Recruit Tumor-Promoting Macrophages to Mouse Gastric Tumors

(2010) Hiroko Oshima et al.   GASTROENTEROLOGY

TGF-β–FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

(2010) Kazuhito Naka et al.   NATURE

Prostaglandin E2, Wnt, and BMP in gastric tumor mouse models

(2009) Hiroko Oshima et al.   CANCER SCIENCE

FOXO3a Promotes Tumor Cell Invasion through the Induction of Matrix Metalloproteinases

(2009) P. Storz et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY