Association of APOE Genotype With Heterogeneity of Cognitive Decline Rate in Alzheimer Disease

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

(2020) Eric M. Reiman et al.   Nature Communications

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

(2020) Axel Montagne et al.   NATURE

Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report

(2019) Joseph F. Arboleda-Velasquez et al.   NATURE MEDICINE

Version 3 of the Alzheimer Disease Centers’ Neuropsychological Test Battery in the Uniform Data Set (UDS)

(2018) Sandra Weintraub et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

The Revised National Alzheimer’s Coordinating Center’s Neuropathology Form—Available Data and New Analyses

(2018) Lilah M Besser et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types

(2018) Yuan-Ta Lin et al.   NEURON

Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study

(2018) Hyun-Sik Yang et al.   LANCET NEUROLOGY

APOE ε4 is associated with severity of Lewy body pathology independent of Alzheimer pathology

(2018) Dennis W. Dickson et al.   NEUROLOGY

Version 3 of the National Alzheimer’s Coordinating Center’s Uniform Data Set

(2018) Lilah Besser et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Attributable risk of Alzheimer's dementia attributed to age-related neuropathologies

(2018) Patricia A. Boyle et al.   ANNALS OF NEUROLOGY

APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes

(2017) Jing Zhao et al.   HUMAN MOLECULAR GENETICS

Estimation of Extended Mixed Models Using Latent Classes and Latent Processes: The R Package lcmm

(2017) Cécile Proust-Lima et al.   Journal of Statistical Software

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

(2017) Yang Shi et al.   NATURE

Neurofibrillary Tangle Stage and the Rate of Progression of Alzheimer Symptoms

(2017) Jing Qian et al.   JAMA Neurology

APOE2eases cognitive decline during Aging: Clinical and preclinical evaluations

(2016) Mitsuru Shinohara et al.   ANNALS OF NEUROLOGY

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

(2016) Jeff Sevigny et al.   NATURE

PET Imaging of Tau Deposition in the Aging Human Brain

(2016) Michael Schöll et al.   NEURON

Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes

(2016) Won-Suk Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APOEε2 is associated with milder clinical and pathological Alzheimer disease

(2015) Alberto Serrano-Pozo et al.   ANNALS OF NEUROLOGY

Mild to moderate Alzheimer dementia with insufficient neuropathological changes

(2014) Alberto Serrano-Pozo et al.   ANNALS OF NEUROLOGY

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

The A4 Study: Stopping AD Before Symptoms Begin?

(2014) R. A. Sperling et al.   Science Translational Medicine

Effect of APOE genotype status on targeted clinical trials outcomes and efficiency in dementia and mild cognitive impairment resulting from Alzheimer's disease

(2013) Richard E. Kennedy et al.   Alzheimers & Dementia

Examination of the Clinicopathologic Continuum of Alzheimer Disease in the Autopsy Cohort of the National Alzheimer Coordinating Center

(2013) Alberto Serrano-Pozo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Brain  -amyloid load approaches a plateau

(2013) C. R. Jack et al.   NEUROLOGY

Apolipoprotein E4 effects in Alzheimer’s disease are mediated by synaptotoxic oligomeric amyloid-β

(2012) Robert M. Koffie et al.   BRAIN

Accuracy of the Clinical Diagnosis of Alzheimer Disease at National Institute on Aging Alzheimer Disease Centers, 2005–2010

(2012) Thomas G. Beach et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Apolipoprotein E, Especially Apolipoprotein E4, Increases the Oligomerization of Amyloid   Peptide

(2012) T. Hashimoto et al.   JOURNAL OF NEUROSCIENCE

Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study

(2012) Christopher M Clark et al.   LANCET NEUROLOGY

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Apolipoprotein E ɛ2 and Functional Decline in Amnestic Mild Cognitive Impairment and Alzheimer Disease

(2011) Aaron Bonner-Jackson et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Factor Structure of the National Alzheimerʼs Coordinating Centers Uniform Dataset Neuropsychological Battery

(2010) Kathleen M. Hayden et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Dysexecutive versus amnesic phenotypes of very mild Alzheimer's disease are associated with distinct clinical, genetic and cortical thinning characteristics

(2010) B. C. Dickerson et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease

(2010) D. A. Wolk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Most rapid cognitive decline in APOE ε4 negative Alzheimer's disease with early onset

(2009) A. E. van der Vlies et al.   PSYCHOLOGICAL MEDICINE

APOE  4 allele predicts faster cognitive decline in mild Alzheimer disease

(2008) S. Cosentino et al.   NEUROLOGY