Sensing and Regulating Synaptic Activity by Astrocytes at Tripartite Synapse

Astrocytes are recognized as more important cells than historically thought in synaptic function through the reciprocal exchange of signaling with the neuronal synaptic elements. The idea that astrocytes are active elements in synaptic physiology is conceptualized in the Tripartite Synapse concept. This review article presents and discusses recent representative examples that highlight the heterogeneity of signaling in tripartite synapse function and its consequences on neural network function and animal behavior.

Automated summary

This review article discusses the importance of astrocytes in synaptic function and the concept of the Tripartite Synapse. It highlights the diversity of signaling and its impact on neural network function and animal behavior.