The HaloTag as a general scaffold for far-red tunable chemigenetic indicators

A general method to optimize and functionalize red-shifted rhodamine dyes

(2020) Jonathan B. Grimm et al.   NATURE METHODS

Spying on Neuronal Membrane Potential with Genetically Targetable Voltage Indicators

(2019) Vincent Grenier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A genetically encoded near-infrared fluorescent calcium ion indicator

(2019) Yong Qian et al.   NATURE METHODS

High-performance calcium sensors for imaging activity in neuronal populations and microcompartments

(2019) Hod Dana et al.   NATURE METHODS

Bright and photostable chemigenetic indicators for extended in vivo voltage imaging

(2019) Ahmed S. Abdelfattah et al.   SCIENCE

Isomeric Tuning Yields Bright and Targetable Red Ca2+ Indicators

(2019) Claire Deo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational Design of Fluorogenic and Spontaneously Blinking Labels for Super-Resolution Imaging

(2019) Qinsi Zheng et al.   ACS Central Science

Covalently Tethered Rhodamine Voltage Reporters for High Speed Functional Imaging in Brain Tissue

(2019) Parker E. Deal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Beyond Fluorescent Proteins: Hybrid and Bioluminescent Indicators for Imaging Neural Activities

(2018) Anqi Wang et al.   ACS Chemical Neuroscience

Fluorogenic Targeting of Voltage-Sensitive Dyes to Neurons

(2017) Pei Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A general method to fine-tune fluorophores for live-cell and in vivo imaging

(2017) Jonathan B Grimm et al.   NATURE METHODS

Genetically encoded indicators of neuronal activity

(2016) Michael Z Lin et al.   NATURE NEUROSCIENCE

Sensitive red protein calcium indicators for imaging neural activity

(2016) Hod Dana et al.   eLife

HaloTag Technology: A Versatile Platform for Biomedical Applications

(2015) Christopher G. England et al.   BIOCONJUGATE CHEMISTRY

Single-trial imaging of spikes and synaptic potentials in single neurons in brain slices with genetically encoded hybrid voltage sensor

(2015) Nima Ghitani et al.   JOURNAL OF NEUROPHYSIOLOGY

A general method to improve fluorophores for live-cell and single-molecule microscopy

(2015) Jonathan B Grimm et al.   NATURE METHODS

High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor

(2014) François St-Pierre et al.   NATURE NEUROSCIENCE

Optically Detected Structural Change in the N-Terminal Region of the Voltage-Sensor Domain

(2013) Hidekazu Tsutsui et al.   BIOPHYSICAL JOURNAL

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

A Neuron-Based Screening Platform for Optimizing Genetically-Encoded Calcium Indicators

(2013) Trevor J. Wardill et al.   PLoS One

Single Action Potentials and Subthreshold Electrical Events Imaged in Neurons with a Fluorescent Protein Voltage Probe

(2012) Lei Jin et al.   NEURON

Imaging Calcium in Neurons

(2012) Christine Grienberger et al.   NEURON

Genetic Targeting of a Voltage-Sensitive Dye by Enzymatic Activation of Phosphonooxymethyl-ammonium Derivative

(2011) David N. Ng et al.   ACS Chemical Biology

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Chemical tags: Applications in live cell fluorescence imaging

(2011) Richard Wombacher et al.   Journal of Biophotonics

Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling

(2011) Jonathan B. Grimm et al.   ORGANIC LETTERS

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Reevaluation of absolute luminescence quantum yields of standard solutions using a spectrometer with an integrating sphere and a back-thinned CCD detector

(2009) Kengo Suzuki et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology