Self-driving armored CAR-T cells overcome suppressive milieu and eradicate CD19+ Raji lymphoma in preclinical models

Title
Self-driving armored CAR-T cells overcome suppressive milieu and eradicate CD19+ Raji lymphoma in preclinical models
Authors
Keywords
Chimeric antigen receptor, CAR, T cell engineering, CAR regulation, tonic signaling, exhaustion, armored CAR, transforming growth factor beta, CD19, lentivirus
Journal
MOLECULAR THERAPY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-05-09
DOI
10.1016/j.ymthe.2021.05.006

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