Endoplasmic reticulum stress-mediated upregulation of miR-29a enhances sensitivity to neuronal apoptosis

Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival

(2015) F Walter et al.   CELL DEATH AND DIFFERENTIATION

Downregulation of E2F1 during ER stress is required to induce apoptosis

(2015) V. Pagliarini et al.   JOURNAL OF CELL SCIENCE

Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice

(2015) Aikaterini S. Papadopoulou et al.   NEUROBIOLOGY OF DISEASE

Salubrinal protects against rotenone-induced SH-SY5Y cell death via ATF4-parkin pathway

(2014) Liang Wu et al.   BRAIN RESEARCH

PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease

(2014) Latha Devi et al.   NEUROBIOLOGY OF AGING

Functional Contribution of the Transcription Factor ATF4 to the Pathogenesis of Amyotrophic Lateral Sclerosis

(2013) Soledad Matus et al.   PLoS One

Changes in MicroRNA Expression Contribute to Pancreatic  -Cell Dysfunction in Prediabetic NOD Mice

(2012) E. Roggli et al.   DIABETES

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

Downregulation of BCL2 by miRNAs augments drug-induced apoptosis - a combined computational and experimental approach

(2012) R. Singh et al.   JOURNAL OF CELL SCIENCE

AMP-activated protein kinase (AMPK)-induced preconditioning in primary cortical neurons involves activation of MCL-1

(2012) Ujval Anilkumar et al.   JOURNAL OF NEUROCHEMISTRY

Integrating insulin secretion and ER stress in pancreatic β-cells

(2012) Katleen Lemaire et al.   NATURE CELL BIOLOGY

Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration

(2012) Rhonda M. Perciavalle et al.   NATURE CELL BIOLOGY

Identification of Novel Targets for miR-29a Using miRNA Proteomics

(2012) Rhishikesh Bargaje et al.   PLoS One

The unfolded protein response and proteostasis in Alzheimer disease

(2011) Wiep Scheper et al.   Autophagy

MiR-29a down-regulation in ALK-positive anaplastic large cell lymphomas contributes to apoptosis blockade through MCL-1 overexpression

(2011) C. Desjobert et al.   BLOOD

Apoptosis and oncogenesis: give and take in the BCL-2 family

(2011) Fabien Llambi et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis

(2011) A. J. Kole et al.   GENES & DEVELOPMENT

Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology

(2011) Giordano Lippi et al.   JOURNAL OF CELL BIOLOGY

miR-29a and miR-29b Contribute to Pancreatic  -Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1)

(2011) T. J. Pullen et al.   MOLECULAR AND CELLULAR BIOLOGY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Downregulation of microRNA-29 by antisense inhibitors and a PPAR-γ agonist protects against myocardial ischaemia–reperfusion injury

(2010) Yumei Ye et al.   CARDIOVASCULAR RESEARCH

Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis

(2010) F Allagnat et al.   CELL DEATH AND DIFFERENTIATION

MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner

(2010) Marc Germain et al.   EMBO JOURNAL

AMP kinase–mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

(2010) Caoimhín G. Concannon et al.   JOURNAL OF CELL BIOLOGY

microRNA expression alteration after arsenic trioxide treatment in HepG-2 cells

(2010) Xian-Zhi Meng et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma

(2010) Satoshi Shimizu et al.   JOURNAL OF HEPATOLOGY

Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4-CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA

(2010) Z. Galehdar et al.   JOURNAL OF NEUROSCIENCE

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice

(2009) Smita Saxena et al.   NATURE NEUROSCIENCE

NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner

(2008) Caoimhín G. Concannon et al.   JOURNAL OF NEUROCHEMISTRY

Mcl-1 Is a Key Regulator of Apoptosis during CNS Development and after DNA Damage

(2008) N. Arbour et al.   JOURNAL OF NEUROSCIENCE

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression

(2008) S. S. Hebert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA