Structural refinement of pyrazolo[4,3- d ]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A 3 adenosine receptor

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Title
Structural refinement of pyrazolo[4,3- d ]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A 3 adenosine receptor
Authors
Keywords
G-protein-coupled receptors, Adenosine receptor antagonists, Pyrazolopyrimidines, Ligand-receptor modeling studies
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 108, Issue -, Pages 117-133
Publisher
Elsevier BV
Online
2015-11-18
DOI
10.1016/j.ejmech.2015.11.015

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