Structural modifications of the serotonin 5-HT7 receptor agonist N-(4-cyanophenylmethyl)-4-(2-biphenyl)-1-piperazinehexanamide (LP-211) to improve in vitro microsomal stability: A case study

Title
Structural modifications of the serotonin 5-HT7 receptor agonist N-(4-cyanophenylmethyl)-4-(2-biphenyl)-1-piperazinehexanamide (LP-211) to improve in vitro microsomal stability: A case study
Authors
Keywords
5-HT, 7, receptor, Arylpiperazine, Microsomal stability, Machine learning, Neurite outgrowth
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 120, Issue -, Pages 363-379
Publisher
Elsevier BV
Online
2016-05-07
DOI
10.1016/j.ejmech.2016.05.005

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