Autonomous Calcium Signaling in Human and Zebrafish Podocytes Controls Kidney Filtration Barrier Morphogenesis

Injured Podocytes Are Sensitized to Angiotensin II–Induced Calcium Signaling

(2020) Julia Binz-Lotter et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Podocytopathies

(2020) Jeffrey B. Kopp et al.   Nature Reviews Disease Primers

Manipulation of Nephron-Patterning Signals Enables Selective Induction of Podocytes from Human Pluripotent Stem Cells

(2019) Yasuhiro Yoshimura et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy

(2019) Janina Müller-Deile et al.   Biology Open

Reporter‐based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation

(2019) Sara E Howden et al.   EMBO REPORTS

In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes

(2019) Tracy Tran et al.   DEVELOPMENTAL CELL

Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome

(2019) Sun-Ji Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Toolbox to Characterize Human Induced Pluripotent Stem Cell–Derived Kidney Cell Types and Organoids

(2019) Jessica M. Vanslambrouck et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Efficacy of Puromycin and Adriamycin for Induction of Glomerular Failure in Larval Zebrafish Validated by an Assay of Glomerular Permeability Dynamics

(2018) Sebastien Andrew Rider et al.   Zebrafish

Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature

(2018) Jenna R. Sternberg et al.   Nature Communications

Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes

(2018) Shunsuke Tanigawa et al.   Stem Cell Reports

3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

(2018) Lorna J. Hale et al.   Nature Communications

Angiotensin II induces calcium/calcineurin signaling and podocyte injury by downregulating microRNA-30 family members

(2017) Yue Zhao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

TRPC5 Does Not Cause or Aggravate Glomerular Disease

(2017) Xuexiang Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Acute podocyte injury is not a stimulus for podocytes to migrate along the glomerular basement membrane in zebrafish larvae

(2017) Florian Siegerist et al.   Scientific Reports

From man to fish: What can Zebrafish tell us about ApoL1 nephropathy?

(2016) Opeyemi Olabisi et al.   CLINICAL NEPHROLOGY

Morphological process of podocyte development revealed by block-face scanning electron microscopy

(2016) Koichiro Ichimura et al.   JOURNAL OF CELL SCIENCE

Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification

(2016) Sven Reischauer et al.   NATURE

Generation of kidney organoids from human pluripotent stem cells

(2016) Minoru Takasato et al.   Nature Protocols

Single and Transient Ca2+ Peaks in Podocytes do not induce Changes in Glomerular Filtration and Perfusion

(2016) Sybille Koehler et al.   Scientific Reports

Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation

(2015) S. Sharmin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

(2015) Minoru Takasato et al.   NATURE

Structural organization of signalling to and from IP3receptors

(2014) Colin W. Taylor et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Shroom3contributes to the maintenance of the glomerular filtration barrier integrity

(2014) Nan Cher Yeo et al.   GENOME RESEARCH

Intravital imaging of podocyte calcium in glomerular injury and disease

(2014) James L. Burford et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis

(2014) Ilse Daehn et al.   JOURNAL OF CLINICAL INVESTIGATION

osr1 Is Required for Podocyte Development Downstream of wt1a

(2014) R. Tomar et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Descending Control of Swim Posture by a Midbrain Nucleus in Zebrafish

(2014) Tod R. Thiele et al.   NEURON

Spatial and Temporal Control of Transgene Expression in Zebrafish

(2014) Alexander A. Akerberg et al.   PLoS One

Phylogeny and expression of canonical transient receptor potential (TRPC) genes in developing zebrafish

(2013) Valentin Von Niederhäusern et al.   DEVELOPMENTAL DYNAMICS

Inhibition of the TRPC5 ion channel protects the kidney filter

(2013) Thomas Schaldecker et al.   JOURNAL OF CLINICAL INVESTIGATION

Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae

(2013) N. Endlich et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish

(2012) Chang-Bin Jing et al.   DEVELOPMENTAL BIOLOGY

Calcium signaling in developing embryos: Focus on the regulation of cell shape changes and collective movements

(2012) Olga Markova et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Calcium Regulates Podocyte Actin Dynamics

(2012) Anna Greka et al.   SEMINARS IN NEPHROLOGY

Inhibitory Effects of Robo2 on Nephrin: A Crosstalk between Positive and Negative Signals Regulating Podocyte Structure

(2012) Xueping Fan et al.   Cell Reports

Comparative analysis of Neph gene expression in mouse and chicken development

(2011) Linus A. Völker et al.   HISTOCHEMISTRY AND CELL BIOLOGY

TRPC6 Enhances Angiotensin II-induced Albuminuria

(2011) J. Eckel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Balancing Calcium Signals through TRPC5 and TRPC6 in Podocytes

(2011) A. Greka et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tyrosine phosphorylation–dependent activation of TRPC6 regulated by PLC-γ1 and nephrin: effect of mutations associated with focal segmental glomerulosclerosis

(2011) Shoichiro Kanda et al.   MOLECULAR BIOLOGY OF THE CELL

Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

(2010) Y. Wang et al.   DEVELOPMENT

Antagonistic Regulation of Actin Dynamics and Cell Motility by TRPC5 and TRPC6 Channels

(2010) D. Tian et al.   Science Signaling

PKC-alpha Modulates TGF-β Signaling and Impairs Podocyte Survival

(2009) Irini Tossidou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Phosphorylation of Nephrin Triggers Ca2+Signaling by Recruitment and Activation of Phospholipase C-γ1

(2009) Yutaka Harita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel TRPC6 Mutation That Causes Childhood FSGS

(2009) Saskia F. Heeringa et al.   PLoS One

Regulation of the renal microcirculation by ryanodine receptors and calcium-induced calcium release

(2008) William J Arendshorst et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Neph1, a Component of the Kidney Slit Diaphragm, Is Tyrosine-phosphorylated by the Src Family Tyrosine Kinase and Modulates Intracellular Signaling by Binding to Grb2

(2008) Yutaka Harita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY