Copper-Catalyzed Transfer Hydrodeuteration of Aryl Alkenes with Quantitative Isotopomer Purity Analysis by Molecular Rotational Resonance Spectroscopy

Bayesian Analysis of Theoretical Rotational Constants from Low-Cost Electronic Structure Methods

(2020) Kin Long Kelvin Lee et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Regiodivergent DH or HD Addition to Alkenes: Deuterohydrogenation versus Hydrodeuterogenation

(2020) Luomo Li et al.   ORGANIC LETTERS

CuH-Catalyzed Olefin Functionalization: From Hydroamination to Carbonyl Addition

(2020) Richard Y. Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Preparation of cyclohexene isotopologues and stereoisotopomers from benzene

(2020) Jacob A. Smith et al.   NATURE

Generalized Chemoselective Transfer Hydrogenation/Hydrodeuteration

(2020) Yong Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Amine‐Boranes as Transfer Hydrogenation and Hydrogenation Reagents: A Mechanistic Perspective

(2020) Samantha Lau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid quantification of isomeric and dehalogenated impurities in pharmaceutical raw materials using MRR spectroscopy

(2020) Justin L. Neill et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Applications of deuterium in medicinal chemistry

(2019) Tracey Pirali et al.   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic α-Selective Deuteration of Styrene Derivatives

(2019) Thomas R. Puleo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deuterated Active Pharmaceutical Ingredients: A Science Based Proposal for Synthesis, Analysis, and Control. Part 1: Framing the Problem

(2019) Boris Czeskis et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

A Gas Chromatography-Molecular Rotational Resonance Spectroscopy Based System of Singular Specificity

(2019) Daniel W. Armstrong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A quantitative LC-MS/MS method for simultaneous determination of deuvortioxetine, vortioxetine and their carboxylic acid metabolite in rat plasma, and its application to a toxicokinetic study

(2018) Mei Qin et al.   Analytical Methods

Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences

(2018) Jens Atzrodt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C−H Functionalisation for Hydrogen Isotope Exchange

(2018) Jens Atzrodt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Room Temperature Iron-Catalyzed Transfer Hydrogenation and Regioselective Deuteration of Carbon–Carbon Double Bonds

(2018) Maialen Espinal-Viguri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regioselective Transfer Hydrodeuteration of Alkenes with a Hydrogen Deuteride Surrogate Using B(C6F5)3 Catalysis

(2018) Johannes C. L. Walker et al.   ORGANIC LETTERS

First deuterated drug approved

(2017) Charles Schmidt   NATURE BIOTECHNOLOGY

Catalyst: Sustainable Catalysis

(2017) Jacob R. Ludwig et al.   Chem

Balancing C=C Functionalization and C=O Reduction in Cu−H Catalysis

(2016) Jens Mohr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deducing Reaction Mechanism: A Guide for Students, Researchers, and Instructors

(2016) Simon J. Meek et al.   JOURNAL OF CHEMICAL EDUCATION

Brønsted Acid-Catalyzed Transfer Hydrogenation of Imines and Alkenes Using Cyclohexa-1,4-dienes as Dihydrogen Surrogates

(2016) Indranil Chatterjee et al.   ORGANIC LETTERS

Transition-Metal Catalysis and Organocatalysis: Where Can Progress Be Expected?

(2015) Qi-Lin Zhou   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Golden Age of Transfer Hydrogenation

(2015) Dong Wang et al.   CHEMICAL REVIEWS

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Copper-Catalyzed Intermolecular Regioselective Hydroamination of Styrenes with Polymethylhydrosiloxane and Hydroxylamines

(2013) Yuya Miki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Broadband Fourier transform rotational spectroscopy for structure determination: The water heptamer

(2013) Cristóbal Pérez et al.   CHEMICAL PHYSICS LETTERS

Using Deuterium in Drug Discovery: Leaving the Label in the Drug

(2013) Thomas G. Gant   JOURNAL OF MEDICINAL CHEMISTRY

Enantio- and Regioselective CuH-Catalyzed Hydroamination of Alkenes

(2013) Shaolin Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Monophasic Catalytic System for the Selective Semireduction of Alkynes

(2013) Aaron M Whittaker et al.   ORGANIC LETTERS

Effects of London dispersion correction in density functional theory on the structures of organic molecules in the gas phase

(2013) Stefan Grimme et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Copper-Catalyzed Highly Selective Semihydrogenation of Non-Polar Carbon-Carbon Multiple Bonds using a Silane and an Alcohol

(2012) Kazuhiko Semba et al.   ADVANCED SYNTHESIS & CATALYSIS

On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition-Metal Complexes

(2012) Eric M. Simmons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isotopic Labeling of Metabolites in Drug Discovery Applications

(2012) Jacobo Iglesias et al.   CURRENT DRUG METABOLISM

Metabolism-guided drug design

(2012) Antonia F. Stepan et al.   MedChemComm

Stereochemical Investigations Reveal the Mechanism of the Bacterial Activation of n-Alkanes without Oxygen

(2011) René Jarling et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Rotational spectroscopy of iodobenzene and iodobenzene–neon with a direct digital 2–8GHz chirped-pulse Fourier transform microwave spectrometer

(2011) Justin L. Neill et al.   JOURNAL OF MOLECULAR SPECTROSCOPY

Kinetic Isotope Effects in Asymmetric Reactions

(2010) Thomas Giagou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pd- and Pt-catalyzed H/D exchange methods and their application for internal MS standard preparation from a Sanofi-Aventis perspective

(2010) Jens Atzrodt et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

A new model for the origin of kinetic hydrogen isotope effects

(2010) Judith P. Klinman   JOURNAL OF PHYSICAL ORGANIC CHEMISTRY

A broadband Fourier transform microwave spectrometer based on chirped pulse excitation

(2008) Gordon G. Brown et al.   REVIEW OF SCIENTIFIC INSTRUMENTS