The Antiviral Enzyme, Viperin, Activates Protein Ubiquitination by the E3 Ubiquitin Ligase, TRAF6
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Title
The Antiviral Enzyme, Viperin, Activates Protein Ubiquitination by the E3 Ubiquitin Ligase, TRAF6
Authors
Keywords
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Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 143, Issue 13, Pages 4910-4914
Publisher
American Chemical Society (ACS)
Online
2021-03-29
DOI
10.1021/jacs.1c01045
References
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Related references
Note: Only part of the references are listed.- Structural Basis of the Substrate Selectivity of Viperin
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- Interactions between Viperin, Vesicle-Associated Membrane Protein A, and Hepatitis C Virus Protein NS5A Modulate Viperin Activity and NS5A Degradation
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- Targeting viperin to the mitochondrion inhibits the thiolase activity of the trifunctional enzyme complex
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- Viperin: an ancient radical-SAM enzyme finds its place in modern cellular metabolism and innate immunity
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- Nanofactories for Controlled Synthesis and Delivery of Nucleoside Analogue Therapeutics
- (2020) Kourosh H. Ebrahimi CHEMBIOCHEM
- Viperin interacts with the kinase IRAK1 and the E3 ubiquitin ligase TRAF6, coupling innate immune signaling to antiviral ribonucleotide synthesis
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- Reconstitution and substrate specificity for isopentenyl pyrophosphate of the antiviral radical SAM enzyme viperin
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- Mechanism of ubiquitin transfer promoted by TRAF6
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- A naturally occurring antiviral ribonucleotide encoded by the human genome
- (2018) Anthony S. Gizzi et al. NATURE
- Tumor Necrosis Factor Receptor-Associated Factor Regulation of Nuclear Factor κB and Mitogen-Activated Protein Kinase Pathways
- (2018) Jian-Hong Shi et al. Frontiers in Immunology
- Interferon-Stimulated Genes as Enhancers of Antiviral Innate Immune Signaling
- (2017) Keaton M. Crosse et al. Journal of Innate Immunity
- RadicalS-Adenosylmethionine Enzymes in Human Health and Disease
- (2016) Bradley J. Landgraf et al. Annual Review of Biochemistry
- Ubiquitin signaling in immune responses
- (2016) Hongbo Hu et al. CELL RESEARCH
- Does Viperin Function as a RadicalS-Adenosyl-l-methionine-dependent Enzyme in Regulating Farnesylpyrophosphate Synthase Expression and Activity?
- (2016) Caitlyn Makins et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The San1 Ubiquitin Ligase Functions Preferentially with Ubiquitin-conjugating Enzyme Ubc1 during Protein Quality Control
- (2016) Rebeca Ibarra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RING-type E3 ligases: Master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination
- (2013) Meredith B. Metzger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The Role of Viperin in the Innate Antiviral Response
- (2013) Karla J. Helbig et al. JOURNAL OF MOLECULAR BIOLOGY
- Antiviral Protein Viperin Promotes Toll-like Receptor 7- and Toll-like Receptor 9-Mediated Type I Interferon Production in Plasmacytoid Dendritic Cells
- (2011) Tatsuya Saitoh et al. IMMUNITY
- Crosstalk in NF-κB signaling pathways
- (2011) Andrea Oeckinghaus et al. NATURE IMMUNOLOGY
- The emerging complexity of protein ubiquitination
- (2009) David Komander BIOCHEMICAL SOCIETY TRANSACTIONS
- Kinetics of the Transfer of Ubiquitin from UbcH7 to E6AP
- (2009) Carrie Purbeck et al. BIOCHEMISTRY
- Detection of sequential polyubiquitylation on a millisecond timescale
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- E2 interaction and dimerization in the crystal structure of TRAF6
- (2009) Qian Yin et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1
- (2007) Alban Ordureau et al. BIOCHEMICAL JOURNAL
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